Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
28/09/2018	Towards an accessible methodology in precision medicine: methods for time-to-event data and non-regular inferences with an application to treatment of type 2 diabetes
03/10/2018	A cross sectional description of prostate cancer subgroups
09/10/2018	Incidence of Cervical Intraepithelial Neoplasia (CIN) among women aged 18 years and above in the UK between 2000 and 2017
11/10/2018	SGLT-2 Inhibitors and the Risk of Community-acquired Pneumonia
11/10/2018	Reproducible Evidence: Practices to Enhance and Achieve Transparency (REPEAT):Study 15 - Replication of "Concurrent use of long-acting bronchodilators in COPD and the risk of adverse cardiovascular events."
11/10/2018	Incretin-based drugs and the risk of lung cancer in patients with type 2 diabetes
12/10/2018	Investigating the cost-effectiveness of interventions to reduce hazardous prescribing associated with antithrombotic drugs in primary care.
12/10/2018	The treatment pathway for female patients diagnosed with breast cancer and differences due to lifestyle factors: A cohort study using the Clinical Practice Research Datalink
12/10/2018	Reproducible Evidence: Practices to Enhance and Achieve Transparency (REPEAT): Study 13 - Replication of "Metformin and the incidence of viral associated cancers in patients with type 2 diabetes."
24/10/2018	Dravet and Lennox-Gastaut Syndromes in the U.K.: epidemiology, patient pathways and costs.
25/10/2018	Development and validation of a prognostic model for use in primary care which estimates the probability of individuals with non-diabetic hyperglycaemia developing type 2 diabetes
25/10/2018	Burden of Hypereosinophilic syndrome (HES) in the UK
25/10/2018	Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study
29/10/2018	SELECT: Selection of Eligible People for Lung Cancer Screening using Electronic Primary Care DaTa: Development of new risk prediction models
29/10/2018	Annual healthcare resource utilisation attributable to meningococcal disease (MD) in the UK during the period 2008-2017 – retrospective database analysis
29/10/2018	Burden of meningococcal disease (MD) in the UK during the period 2008-2017 - retrospective database analysis
30/10/2018	Assessing the Chronicity and Burden of Hyperkalaemia in Patients with Cardiorenal Comorbidities
30/10/2018	Reproducible Evidence: Practices to Enhance and Achieve Transparency (REPEAT):Study 15 - Replication of "Concurrent use of long-acting bronchodilators in COPD and the risk of adverse cardiovascular events."
31/10/2018	The burden of respiratory disease in people living with HIV infection in the UK Clinical Practice Research Datalink
31/10/2018	Respiratory Syncytial Virus (RSV) healthcare burden in England during the period 2007-2017