Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
10/02/2016	Evaluating the utility of the CPRD GOLD-HTI linkage: anticoagulant prescribing at the GP practice compared to hospital dispensed medication at discharge date
10/02/2016	Depression, prescription of antidepressant drugs and changes in body weight: A cohort study using electronic health records
11/02/2016	Using Linked Primary and Secondary Care Data to Explore Complex Pathways Through Complex Systems for Patients with Long-Term Conditions
16/02/2016	Characterising the safety profile of lurasidone in clinical practice: A drug utilisation and safety study using a United Kingdom primary care database.
16/02/2016	Cancer Survival Programme and Early Diagnosis of Cancer
16/02/2016	Serum creatinine elevation following renin-angiotensin-aldosterone system blockade, adherence to monitoring and discontinuation guidelines, and long-term cardiorenal risks
18/02/2016	Use of routinely collected national data to determine the delays that lead to poor outcome for cancer patients in the UK
19/02/2016	Investigating the effects of commonly prescribed drugs on the prevention and treatment of Alzheimer's and other neurodegenerative diseases: are there drugs already available that can be repurposed?
23/02/2016	Association between HbA1c and all-cause mortality in people with type 2 diabetes treated with glucose-lowering therapies with a higher and lower risk of inducing hypoglycaemia: a retrospective cohort study.
23/02/2016	Epidemiology of venous thromboembolism in patients with active cancer: a population-based cohort study
23/02/2016	Risk of hypoglycaemia in users of sulphonylureas with renal impairment: a population-based cohort study
23/02/2016	Comorbidity in the aging HIV population of the UK: a CPRD analysis.
24/02/2016	The last year of life in COPD: prognostication, preparation, palliation
25/02/2016	Predicting first admission and readmission in heart failure patients
25/02/2016	Validity of UK general practice prescribing safety indicators in predicting adverse events
25/02/2016	Risks and benefits of bisphosphonate use in patients with chronic kidney disease: a population-based cohort study
08/03/2016	Natural history, characteristics, and treatment patterns in patients with primary biliary cirrhosis and cholestatic pruritis
09/03/2016	Predictors of complications of venous thromboembolism
10/03/2016	Investigating the utility of blood pressure variability in cardiovascular risk prediction
11/03/2016	The characteristics of rheumatoid arthritis patient organisation members and online community members with rheumatoid arthritis compared to the general rheumatoid arthritis population