Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Date of Approval Sort descending Title
27/08/2021 Association between degree of weight loss and reduction in risk of developing obesity related complications in adults living with obesity
27/08/2021 Evaluating the performance of cutting-edge statistical methods in reducing confounding bias using plasmode simulations of electronic health record data
27/08/2021 Parkinson's Disease in minority ethnic groups: understanding phenotypical traits and differences in outcomes to inform pathways of care
27/08/2021 Analysis of the Clinical Practice Research Datalink (CPRD Gold + Aurum) and Hospital Episode Statistics (HES) to provide real world evidence on disease progression and the burden of uncomplicated urinary tract infection (uUTI)
27/08/2021 COVID-19 and incidence of venous thromboembolism (VTE) in the UK general population
27/08/2021 Clinical outcomes from robotic colorectal surgery in England: a national study using routinely collected data
27/08/2021 Evaluating treatment patterns of venous thromboembolism patients in primary care
03/09/2021 Dose distributions of the injectable glucagon-like peptide-1 receptor agonists dulaglutide and semaglutide in patients with type 2 diabetes in UK primary care
03/09/2021 UKPREG: UKPREGnancy study - a longitudinal international registry-based cohort study of pregnancy and heart disease
03/09/2021 How many UK patients developed kidney failure since the year 2000? What treatments did they receive and what were their health outcomes?
06/09/2021 Comparative effectiveness of combination therapies on mortality in chronic obstructive pulmonary disease (COPD)
06/09/2021 The impact of painful musculoskeletal conditions on outcomes of dementia
06/09/2021 A study to assess the feasibility of using CPRD-HES linked data to investigate treatment of anemia in pregnancy and postpartum using oral and intravenous iron
06/09/2021 Preventing Unscheduled Hospitalisations from Asthma: a retrospective cohort study using routine primary and secondary care data in the UK (The PUSH-Asthma Study)
06/09/2021 Feasibility study of the data characterisation of the Innovative Medicines Initiative ConcePTION common data model applied to CPRD GOLD
06/09/2021 Impact of prompt versus delayed initiation of single-inhaler triple therapy among patients with Chronic Obstructive Pulmonary Disease in England in real-world primary and secondary care settings
10/09/2021 Predicting Psoriatic Arthritis (PREDIPSA) - Dynamic modelling of primary care health-records for earlier diagnosis of psoriatic arthritis: a population-based study
10/09/2021 Descriptive analysis of trends in health care use in England by ethnicity and deprivation over the austerity period culminating in the COVID-19 pandemic
10/09/2021 Pregnancy induced hypertension, gestational diabetes, and the risk of chronic kidney disease: A population-based study using the Clinical Practice Research Datalink.
10/09/2021 Healthcare resources utilisation and associated costs of adult Attention deficit hyperactivity disorder in England: A retrospective database study