Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
16/09/2021	Describing causes of mortality in different subpopulations of people with Chronic Obstructive Pulmonary Disease and determining factors that may be associated with specific causes of death
16/09/2021	Cohort monitoring of Adverse Events of Special Interest and COVID-19 diagnoses prior to and after COVID-19 vaccination
16/09/2021	Non-invasive tests as prognostic biomarkers of liver events, cardiovascular events and all-cause mortality in individuals with obesity and or type 2 diabetes living in the United Kingdom: a longitudinal cohort study
17/09/2021	Comparative effectiveness of second line glucose lowering therapies on preserving renal function in patients with type 2 diabetes
17/09/2021	Characterising surgery for wrist arthritis and its outcomes
20/09/2021	Prevalence of poorly controlled asthma and factors associated with specialist referral in those with poorly controlled asthma in a paediatric asthma population.
20/09/2021	Real-World Open Angle Glaucoma (OAG) Disease Management, Treatment Patterns, Resource Utilization, and Outcomes from Primary Care through to Secondary Care in the UK Setting
20/09/2021	Understanding the contribution of influenza vaccines to antibiotic prescribing in the UK population: A longitudinal analysis
20/09/2021	Statin Treatment Options during vaccination against inFLUenza (STOPFlu) : a observational study of the interaction between statins and influenza vaccination
20/09/2021	Effects of the COVID-19 pandemic on primary care recorded anxiety and depression, and psychotropic prescribing.
20/09/2021	Early warning score for Autism Spectrum Disorder using real-world data
23/09/2021	Characterising the risk of malignancy in patients with atopic dermatitis prescribed immune suppressive medications
23/09/2021	Multimorbidity between chronic diseases in the ageing populations
23/09/2021	Use of machine learning to improve the prediction of 10-years Cardiovascular Disease risk using data from Electronic Health Records
27/09/2021	Mental health, substance abuse and risk of suicide in individuals with physical illness and neurodevelopmental disorders
27/09/2021	Common vaccines and the risk of incident dementia
27/09/2021	Linked Clinical Practice Research Datalink (CPRD)-Hospital Episode Statistics (HES) study to identify the burden of respiratory syncytial virus (RSV) in hospitalised children under 2 years of age
27/09/2021	Prevalence and description of chronic obstructive pulmonary disease cohorts from 2000 to 2020
27/09/2021	Delivery of smoking cessation and alcohol interventions in primary care in the UK
01/10/2021	Defining disease patterns in adults with chronic pain and multimorbidity