Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
01/10/2021	The epidemiology of type 1 and type 2 diabetes in the United Kingdom and the healthcare care cost and resource use associated with managing these conditions
01/10/2021	Defining disease patterns in adults with chronic pain and multimorbidity
01/10/2021	Long-term health in cancer survivors compared with the general population: matched cohort study using linked UK electronic health records
01/10/2021	Use of inhaled corticosteroids in a primary care chronic obstructive pulmonary disease population and risk of cardiovascular disease
01/10/2021	The burden of rotator cuff tear in England: a retrospective cohort study of electronic primary healthcare records from the Clinical Practice Research Datalink and linked secondary care records from Hospital Episodes Statistics
05/10/2021	Trends in continuity of care in general practice: the impact of digital-first primary care on continuity of care before and during COVID-19
05/10/2021	Post-Conditional Approval Active Surveillance Study Among Individuals in Europe Receiving the Pfizer-BioNTech Coronavirus Disease 2019 (COVID-19) Vaccine
05/10/2021	Maternal Vaccination in the NHS (MAVIS) Study: Exploring the characteristics associated with (pertussis and influenza) vaccination in pregnant women
05/10/2021	Retrospective cohort study assessing medication coverage in prostate cancer patients prescribed Luteinizing Hormone Releasing Hormone agonists (LHRH).
05/10/2021	Residual excessive daytime sleepiness in obstructive sleep apnoea treated with continuous positive airway pressure in England: a retrospective cohort study using the clinical practice research datalink linked to hospital episodes statistics
08/10/2021	Comparison of effectiveness and safety of direct oral anticoagulant versus low molecular weight heparin treatment for active cancer-associated venous thromboembolism
08/10/2021	The safety of antipsychotic drugs in children and youth with attention deficit and hyperactivity disorder
08/10/2021	The effectiveness of faster aspart insulin versus other bolus insulins on glycaemic control in a real-world setting
08/10/2021	Aclidinium Bromide Post-Authorization Safety Study (PASS) to Evaluate the Risk of Cardiovascular Endpoints: Arrhythmias
11/10/2021	Atherosclerosis following Deep Vein Thrombosis (ADVenT) study
12/10/2021	Influenza and pneumococcal vaccination in adults with common inflammatory conditions treated with immune suppressing drugs: a study of vaccine uptake, clinical effectiveness and vaccine safety.
15/10/2021	Examining patterns and clusters of comorbidities in people with psoriasis
15/10/2021	Estimated prevalence of multiple long term conditions
19/10/2021	Falling through the cracks: patterns of care for people with markedly elevated blood pressure seen in English primary care
26/10/2021	What biopsychosocial factors are associated with abortions in primary care in Britain? A case control study comparing women aged 13 to 54 who had abortions compared with those who did not.