Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Approved studies using CPRD Data

Date of Approval	Title
29/07/2022	Ethnic Disparities in Quality of Care Among Type 2 Diabetic Patients Before and During the COVID-19 Pandemic: A Before and After Study Using UK Electronic Health Records
01/06/2022	Trends and inequalities in statin use for the primary and secondary prevention of cardiovascular disease
28/04/2022	Safety of COVID-19 vaccination during pregnancy in England: a cohort study
23/03/2022	Healthcare Resource Utilisation and Associated Costs in Patients with COVID-19 in England: A Retrospective Cohort Study
18/03/2022	The impact of COVID-19 pandemic on health care service provision for patients with newly diagnosed cancer
18/03/2022	Characterizing long COVID patients across pre-existing physical and mental health conditions: Risk profiling using Electronic Health Records in the United Kingdom
14/03/2022	Psychiatric diagnoses and self-harm episodes among children and young people in UK primary care records before and during the COVID-19 pandemic: a population-based cohort study
14/03/2022	Investigating disruptions in primary care as a result of the COVID-19 pandemic and the introduction of national lockdowns
09/03/2022	Has the incidence of giant cell arteritis in England and Northern Ireland been influenced by the covid-19 pandemic? A case cohort study using CPRD Aurum data
08/03/2022	Variations in the management of Inflammatory Bowel Disease over time: How has Covid-19 effected inflammatory bowel disease patients?
24/02/2022	The Incidence of Common Autoimmune Diseases in People with COVID-19: a Retrospective Cohort Study using the Clinical Practice Research Datalink.
21/02/2022	Post-Authorization Active Surveillance Safety Study Using Secondary Data to Monitor Real-World Safety of Spikevax in Europe
01/02/2022	How the predictions of algorithms used in healthcare provision change: an investigation using COVID-19 and Cardiovascular disease risk prediction case studies.
27/01/2022	An observational retrospective cohort study describing clinical outcomes and utilisation of healthcare resources among persons with COVID-19 in England, stratified by infection severity and selected comorbidities
05/01/2022	Impact of the coronavirus disease (COVID-19) pandemic on incidence of tics in children and young people: a population-based cohort study
23/12/2021	RECORD-HF: A REtrospective COhort study of heart failure-Related outcomes in patients who are prescribed a loop Diuretic without a diagnosis of Heart Failure
23/12/2021	Patterns and clinical outcomes of cardiovascular medication use after a cancer diagnosis in patients with heart failure
23/12/2021	A post-authorisation (post-marketing) observational study using existing secondary health data sources to evaluate the association between exposure to the AstraZeneca COVID-19 vaccine (AZD1222) and safety concerns
23/12/2021	Comparative effectiveness of Umeclidinium+Vilanterol versus Tiotropium Bromide+Olodaterol among patients with Chronic Obstructive Pulmonary Disease in a real-world primary care setting in the UK
23/12/2021	Do features occurring prior to MS diagnosis vary according to background: a nested case control study