Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
11/09/2015	Healthcare resource utilisation and economic impact among liver transplant patients during the last year before graft failure in the UK: a retrospective observational study
11/09/2015	Healthcare resource utilisation and economic impact among kidney transplant patients during the last year before graft failure in the UK: a retrospective observational study
14/09/2015	The incidence of Guillain-Barre Syndrome in the United Kingdom from April 2005 to March 2015.
15/09/2015	Assessing channelling bias and effectiveness in newly marketed glucose-lowering medications - a retrospective cohort study
15/09/2015	Can Continuity Of Primary Care Decrease Unscheduled Secondary Care Use?
18/09/2015	Study to investigate the drug treatment for sialorrhoea in children over the past 10 years.
22/09/2015	The risk of fragility fracture in inflammatory arthritis: evidence for the effective and equitable targeting of prevention
23/09/2015	Evidence for and implications of channeling in the use of nonprescription acetaminophen and ibuprofen in an electronic medical records database
28/09/2015	Secondary prevention of acute coronary syndrome: comparative effectiveness of recommended vs. less intensive drug combination using Clinical Practice Research Datalink (CPRD). The SCARFACE-CPRD study.
02/10/2015	Evaluation of the clinical and economic outcomes associated with Bydureon versus basal insulin in people with type 2 diabetes
02/10/2015	Developing insights into treatment of chronic/diabetic kidney disease (CKD/DKD) using real world data
02/10/2015	Statins for Prevention of Cardiovascular Disease in Older Primary Care UK Patients
05/10/2015	An evaluation of the epidemiology and burden of illness of congenital adrenal hyperplasia in the United Kingdom
06/10/2015	The association between Huntington's disease and cancer before and after the Huntington's diagnosis - a two-phase study
06/10/2015	What is the burden of foot and ankle pain in the general population of the United Kingdom as recorded by General Practitioners?
06/10/2015	Investigation of long-term outcomes and healthcare utilisation of survivors of critical illness
06/10/2015	Effects of pulmonary rehabilitation on exacerbation number and severity in people with Chronic Obstructive Pulmonary Disease
08/10/2015	Incidence of corticosteroid related adverse events in inflammatory musculoskeletal conditions
08/10/2015	The risk of depression and suicidality in patients with psoriasis, psoriatic arthritis or ankylosing spondylitis: a retrospective United Kingdom database analysis
12/10/2015	Estimating the healthcare use and costs of children born to pregnant smokers