Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Date of Approval Sort ascending Title
13/06/2023 Real-world insights into the early treatment effects of dapagliflozin among patients with chronic kidney disease in UK clinical setting: an observational study
13/06/2023 Risk factors, development of complications, and mortality in individuals with type 1 and type 2 diabetes
13/06/2023 Use of leukotriene receptor antagonists (LTRAs) among patients with asthma in the UK primary care: a drug utilisation study
13/06/2023 Association between menopause and prognosis in dilated cardiomyopathy
12/06/2023 Using big data to investigate fetal and child outcomes following exposure to antiseizure medication in pregnancy
09/06/2023 Risk of cardiovascular events according to treatments patterns in patients with autoimmune disorders
07/06/2023 Defining an evidence base for the use of Advice and Guidance Referrals (BADGER)
07/06/2023 Community benzodiazepine and z-drug hypnotic prescribing after critical illness and the risk of emergency hospital readmission and death: a retrospective cohort study using the United Kingdom Clinical Practice Research Datalink (CPRD)
07/06/2023 External validation of longitudinal predictive models of health-related outcomes in patients older than 65 years of age
05/06/2023 TNEPIX: Trigeminal Neuralgia epidemiology and informatics for characterising disease occurrence, patient journeys, healthcare impact and early diagnostic indications as an evidence package for establishment of UK specialist care centres
05/06/2023 Prevalence and Incidence of Duchenne Muscular Dystrophy in England
05/06/2023 Therapeutic inertia and its association with healthcare resource utilisation, complications, and costs in individuals with uncontrolled type 2 diabetes: a UK population-based retrospective analysis
05/06/2023 PREdictors for DiabetIC Ketoacidosis at Diagnosis of Type 1 Diabetes (The PREDICT project)
05/06/2023 Mental health outcomes in people with diabetes by health behaviours and body mass index
05/06/2023 Longitudinal Assessment of Ethnicity Completeness and Distributions in CPRD Aurum
05/06/2023 Disease burden in primary hyperoxaluria: a cohort study
01/06/2023 Examining comorbidities of patients with childhood onset rheumatic diseases: Juvenile Idiopathic Arthritis (JIA), Juvenile Lupus (jSLE) and Juvenile Dermatomyositis (JDM)
01/06/2023 Patterns of multiple morbidity in people with Down syndrome compared to the general population and people with other intellectual disabilities: a cohort study
24/05/2023 Health Inequalities and Impact of Faecal Immunochemical Testing (FIT) in Symptomatic Patients with suspected colorectal cancer (HIFITS)
24/05/2023 The impact of multimorbidity during pregnancy on maternal and child health and developmental outcomes