Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
27/04/2023	Associations between ethnicity, migration status and deprivation on the primary care service use of children and young people in the UK
27/04/2023	Characterisation of Medication Clusters Prior to and Following Dementia Diagnosis: A Population-Based Descriptive Study
25/04/2023	Non-cancer diagnoses and risk and costs of missed opportunities to diagnose symptomatic cancer: matched case-control and restrospective cohort studies
25/04/2023	Covid-19: impact on recorded incidence of cancer in England in the CPRD
24/04/2023	Feasibility study: To explore the risk of influenza hospitalization among different age groups during influenza seasons 2017-18, 2018-19, and 2019-20, in England
20/04/2023	Association between hypertensive disorders of pregnancy and dilated cardiomyopathy
20/04/2023	Short and long-term impacts of SARS-CoV-2 infection on healthcare use in children
20/04/2023	The prevalence of autoimmune conditions among pregnant women and bidirectional association with pregnancy complications.
20/04/2023	Network models for the prediction of adverse outcomes for patients with multimorbidity and polypharmacy
20/04/2023	Classification and outcomes of perinatal anxiety: implications for practice
17/04/2023	Association between PCOS and Microvascular complications among women with Type 2 Diabetes: a retrospective cohort study
17/04/2023	Safety of the Novavax COVID-19 vaccine in England using a self-controlled case series design: a post-authorisation safety study using data from Clinical Practice Research Datalink (CPRD) Aurum and linked databases
17/04/2023	Feasibility Database study to quantify the number of Lennox-Gastaut syndrome (LGS) and LGS-like patients in the UK
14/04/2023	Associations between cardiovascular, bleeding and mortality outcomes and the co-prescriptions of oral anticoagulants and other medications
12/04/2023	A retrospective cohort study of non-alcoholic steatohepatitis clinical outcomes and economic burden
12/04/2023	Feasibility study to see if two new NICE (National Institute for Health and Care Excellence) indicators on chronic kidney disease (CKD) can be measured successfully at general practice-level
11/04/2023	Artificial Intelligence and Frailty: Discovering Frailty Subtypes with Different Prognostic Profiles
11/04/2023	Exploring the effect of Chronic Obstructive Pulmonary Disease (COPD) on subsequent cardiovascular (CV) events in people with prior major CV event or are at elevated CV risk
06/04/2023	CoMPuTE: Complex Multiple Long Term Conditions - Phenotypes, Trends, and Endpoints
05/04/2023	The risk of acute infection in new users of antihypertensive drugs: a cohort study