Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Approved studies using CPRD Data

Date of Approval Sort ascending Title
07/10/2021 Comparison of effectiveness and safety of direct oral anticoagulant versus low molecular weight heparin treatment for active cancer-associated venous thromboembolism
07/10/2021 The safety of antipsychotic drugs in children and youth with attention deficit and hyperactivity disorder
04/10/2021 Trends in continuity of care in general practice: the impact of digital-first primary care on continuity of care before and during COVID-19
04/10/2021 Residual excessive daytime sleepiness in obstructive sleep apnoea treated with continuous positive airway pressure in England: a retrospective cohort study using the clinical practice research datalink linked to hospital episodes statistics
04/10/2021 Post-Conditional Approval Active Surveillance Study Among Individuals in Europe Receiving the Pfizer-BioNTech Coronavirus Disease 2019 (COVID-19) Vaccine
04/10/2021 Retrospective cohort study assessing medication coverage in prostate cancer patients prescribed Luteinizing Hormone Releasing Hormone agonists (LHRH).
04/10/2021 Maternal Vaccination in the NHS (MAVIS) Study: Exploring the characteristics associated with (pertussis and influenza) vaccination in pregnant women
30/09/2021 Defining disease patterns in adults with chronic pain and multimorbidity
30/09/2021 The epidemiology of type 1 and type 2 diabetes in the United Kingdom and the healthcare care cost and resource use associated with managing these conditions
30/09/2021 Long-term health in cancer survivors compared with the general population: matched cohort study using linked UK electronic health records
30/09/2021 Cardiovascular risk prediction in Rheumatic Diseases
30/09/2021 Use of inhaled corticosteroids in a primary care chronic obstructive pulmonary disease population and risk of cardiovascular disease
30/09/2021 The burden of rotator cuff tear in England: a retrospective cohort study of electronic primary healthcare records from the Clinical Practice Research Datalink and linked secondary care records from Hospital Episodes Statistics
26/09/2021 Common vaccines and the risk of incident dementia
26/09/2021 Mental health, substance abuse and risk of suicide in individuals with physical illness and neurodevelopmental disorders
26/09/2021 Delivery of smoking cessation and alcohol interventions in primary care in the UK
26/09/2021 Linked Clinical Practice Research Datalink (CPRD)-Hospital Episode Statistics (HES) study to identify the burden of respiratory syncytial virus (RSV) in hospitalised children under 2 years of age
26/09/2021 Prevalence and description of chronic obstructive pulmonary disease cohorts from 2000 to 2020
22/09/2021 Characterising the risk of malignancy in patients with atopic dermatitis prescribed immune suppressive medications
22/09/2021 Use of machine learning to improve the prediction of 10-years Cardiovascular Disease risk using data from Electronic Health Records