Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
23/12/2015	Incidence and Prevalence of the Parkinson's Disease in the United Kingdom during 1987-2014
23/12/2015	Novel Prediction Models for the One-Year Competing Risks of Death, Stroke, Intracranial Hemorrhage, and Extracranial Hemorrhage in Adults with Incident Non-Valvular Atrial Fibrillation
29/12/2015	Prescribing of antidepressants and adverse outcomes in patients with chronic kidney disease
30/12/2015	Quality and completeness of recording of social factors related to vaccine uptake in linked electronic health records
31/12/2015	Validation of the recording of asthma diagnosis in adult patients in the Clinical Practice Research Datalink
31/12/2015	Association between Diabetes Mellitus and Incident Meniere's Disease
04/01/2016	Domperidone and risk of primary liver cancer in the UK Clinical Practice Research Datalink
12/01/2016	The risk of Clostridium Difficile Colitis and of pneumonia in persons with pernicious anaemia.
12/01/2016	Maternal Depression and Antidepressant Use During Pregnancy and Risk of Childhood Autism Spectrum Disorders (ASD) in Offspring: Population-based Cohort and Bidirectional Case-Crossover Sibling Study
14/01/2016	Burden of Multiple Myeloma (MM) in England: regional equity based on Real world data from CPRD HES, and Cancer Registry linked data.
14/01/2016	Risk factors for influenza-related complications in children
22/01/2016	Treatment of first-time traumatic anterior shoulder dislocation (UK.TASH-D Study)
22/01/2016	Assessing the Management and Clinical Outcomes of Patients with Non-Diabetic Intermediate Hyperglycaemia in UK Primary Care
28/01/2016	Statin use and incident Achilles or biceps tendon rupture
28/01/2016	Temporal Trend of Severe Hypoglycaemia and Diabetic Ketoacidosis and the Relationship Between HbA1c or HbA1c variability and Risk of Severe Hypoglycaemia and Diabetic Ketoacidosis
02/02/2016	Bleeding Events and oral Anticoagulant Treatment in non-valvular atrial fibrillation (Heart-BEAT study): a cohort study based on CPRD-HES data
09/02/2016	Does better quality of primary care influence admissions and health outcomes for people with serious mental illness (SMI)? A linked patient-level analysis of the full patient care pathway
10/02/2016	Drospirenone-containing combined oral contraceptives and risk of venous thromboembolism
10/02/2016	Depression, prescription of antidepressant drugs and changes in body weight: A cohort study using electronic health records
10/02/2016	Demography and pattern of causes of death in recognised alcohol misusers in the English General Practice (GP) population