Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Date of Approval Sort ascending Title
25/09/2023 A feasibility study to estimate subgroups of atrial fibrillation population
22/09/2023 An observational study program to investigate the management and consequences of hyperkalemia in cardiorenal patients in routine clinical practice
22/09/2023 Use of systemic fluoroquinolones in the UK: a drug utilisation study
21/09/2023 Artificial intelligence to identify medications in primary care associated with increased risk of keratinocyte skin cancer; an exploratory and nested case control study.
20/09/2023 Cardiovascular risk with discontinuation of sodium-containing medications after a hypertension diagnosis
20/09/2023 Management of people with asthma in primary care by smoking status: a descriptive cohort study
20/09/2023 A descriptive study measuring the uptake of NICE (National Institute for Health and Care Excellence) guidance on cardiovascular disease risk assessments and lipid lowering therapies for primary and secondary prevention of cardiovascular disease
20/09/2023 Linaclotide Safety Study for the Assessment of Diarrhoea Complications and Associated Risk Factors in the UK population with Irritable Bowel Syndrome predominantly with constipation (IBS-C)
18/09/2023 Multi-region evaluation of the national roll out of social prescribing link workers in primary care
15/09/2023 "Cancer prevention, screening, diagnosis and prognosis in people with learning disabilities
14/09/2023 Dental patient encounters in general medical practices: a real-world evidence study
14/09/2023 Long-term real-world effectiveness of glucagon-like peptide-1 receptor agonists compared to dipeptidyl peptidase 4 inhibitors on clinical liver events among individuals with T2D living in England: a longitudinal cohort study
14/09/2023 Reproducibility of estimates of prevalence of rare blood cancers from DARWIN EU in the Clinical Practice Research Datalink from primary care sources and assessing the impact of including hospital derived data
14/09/2023 From symptoms to first acute exacerbation of chronic obstructive pulmonary disease: what has changed over time?
11/09/2023 Validation of the Birmingham Lung Improvement Studies (BLISS) prognostic score for predicting acute respiratory admissions among Chronic Obstructive Pulmonary Disease (COPD) patients
11/09/2023 A case-control study of dementia in people taking three commonly prescribed medications: rizatriptan, beclometasone and allopurinol
08/09/2023 Treatment patterns and drug utilisation for medicines of regulatory interest in autoimmune disease
08/09/2023 The presence of obstructive sleep apnoea and the risk of cardiovascular disease in individuals with atrial fibrillation
08/09/2023 Care interventions in the development of heart failure and frailty and their impact on outcomes: a cohort study
06/09/2023 Association of sodium glucose cotransporter 2 inhibitors and glucagon-like peptide-1 receptor agonists with the risk of developing dementia in people with type 2 diabetes