Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Approved studies using CPRD Data

Date of Approval Sort ascending Title
29/07/2021 Event Rates and Risk factors for Cardiovascular Events in a United Kingdom Population with Hypertension
29/07/2021 Incretin-based drugs and the incidence of prostate cancer among patients with type 2 diabetes
22/07/2021 A risk prediction model to predict incident heart failure (RiskHF): derivation and validation cohort study
22/07/2021 Identifying the clinical risks associated with COVID-19 in patients with congenital heart disease and associated co-morbidities
19/07/2021 Event Rates and Risk Factors for Atherosclerotic Cardiovascular Disease Events in High-Risk Primary Prevention and Atherosclerotic Cardiovascular Disease Populations in United Kingdom
13/07/2021 Alternative Confounding Control Approaches for the Prevalent New User Study Design: An Empirical Example Assessing the Effects of Antidiabetic Drug Exposure (sulfonylureas and GLP-1 analogs) on Hospitalization for Heart Failure
11/07/2021 Evaluation of the real-world safety of angiotensin-converting enzyme inhibitors on the risk of lung cancer
09/07/2021 Managing cardiovascular disease and risk in Covid-19 patients in primary care medicine
08/07/2021 An evaluation of the prevalence, epidemiology and burden of illness of bone and joint infections in the United Kingdom: a retrospective observational cohort study
08/07/2021 Trends in primary care prescribing of benzodiazepines, antipsychotics and beta-blockers for anxiety.
08/07/2021 Managing cardiovascular disease and risk in Covid-19 patients in primary care medicine
08/07/2021 Risk of Venous Thromboembolism After Knee, Hip or Shoulder Replacement: A Retrospective Cohort Study Using Linked Hospital and Primary Care Data
06/07/2021 The effect of increasing physician workload on the choice of referrals to secondary care units and lab tests
05/07/2021 Age-specific mortality rates of males diagnosed with Duchenne Muscular Dystrophy.
04/07/2021 Estimating national and local prevalence of mental health conditions during perinatal period in England: an exploratory study
04/07/2021 The prevalence and healthcare utilization of rescue medication users for seizure emergency management in the UK community: a CPRD retrospective database study
04/07/2021 An observational study to generate machine learning and statistical models to predict suicide using Clinical Practice Research Datalink (CPRD) electronic health records.
30/06/2021 Antipsychotics and risk of falls in people with Alzheimer's Disease and agitation. A self-controlled case series study and cohort study
30/06/2021 Development of a Pregnancy Register in the CPRD Aurum database.
30/06/2021 Socio-economic inequalities in prevalence and management of long-term conditions in primary care: a descriptive study