Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
01/09/2023	Inequalities in unplanned hospital admission and the role of continuity of care.
01/09/2023	Temporal trends in and health conditions associated with "Deaths of Despair" (suicides, alcohol- and drug-related deaths): analysis of interlinked primary and secondary healthcare and mortality records
01/09/2023	The association between the COVID-19 vaccine and herpes zoster, bullous pemphigoid and urticaria
30/08/2023	The association between multimorbidity and subsequent dementia: a descriptive cohort study in a representative UK database
30/08/2023	Exploring the feasibility of CPRD to characterise the health of older people living in poverty
30/08/2023	Treatment Patterns in Dermatomyositis Patients in the UK: A Cohort Study using Clinical Practice Research Data Link (CPRD)
29/08/2023	Association between propensity to prescribe antibiotics for common infections in primary care and adverse outcomes
29/08/2023	Risk of Osteonecrosis of the Jaw in Female Users of Osteoporosis Treatments
22/08/2023	Primary care for care home residents: Changes over time before and through the COVID-19 pandemic
22/08/2023	Global COVID Vaccine Safety (GCoVS) Project Investigating COVID-19 Vaccination and Adverse Events, including Myocarditis, Pericarditis, Guillain-Barre Syndrome and Vaccine Induced Thrombosis and Thrombocytopenia: A Self-controlled case series study.
22/08/2023	Changes in survival, and causes of death in people with idiopathic pulmonary fibrosis in England, 2010 to 2022
22/08/2023	Characterisation of Medication Utilisation and Clusters Prior to, During and After Pregnancy: A Population-Based Descriptive Study
21/08/2023	Feasibility Study to Assess the Recording of Endocrine Therapy Use and Induced Vasomotor Symptoms among Women with Breast Cancer in the UK
16/08/2023	Understanding and addressing socio-economic inequality within the quality and safety of care and outcomes for people living with dementia.
15/08/2023	Chronic pain and opioid prescribing in the local health economy: the trends in prevalence and incidence and associated healthcare resource utilisation
15/08/2023	Feasibility and assessment of the association between opioid use and the development of diverticulitis
14/08/2023	Vascular disease and cancer: cohort studies of adult cancer populations and outcomes
10/08/2023	Enhancing Autism Spectrum Disorder (ASD) Research in the United Kingdom: Prevalence Estimation and Comparative Assessment of Conventional Regression and Machine Learning Models for ASD Risk Prediction
09/08/2023	A treat to target approach for obesity management: exploring potential treatment targets
09/08/2023	The risk of adverse psychiatric and somatic outcomes with gabapentinoid use: a UK population-based study using electronic health records