Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
09/07/2021	Trends in primary care prescribing of benzodiazepines, antipsychotics and beta-blockers for anxiety.
09/07/2021	An evaluation of the prevalence, epidemiology and burden of illness of bone and joint infections in the United Kingdom: a retrospective observational cohort study
09/07/2021	Managing cardiovascular disease and risk in Covid-19 patients in primary care medicine
12/07/2021	Evaluation of the real-world safety of angiotensin-converting enzyme inhibitors on the risk of lung cancer
14/07/2021	Alternative Confounding Control Approaches for the Prevalent New User Study Design: An Empirical Example Assessing the Effects of Antidiabetic Drug Exposure (sulfonylureas and GLP-1 analogs) on Hospitalization for Heart Failure
20/07/2021	Event Rates and Risk Factors for Atherosclerotic Cardiovascular Disease Events in High-Risk Primary Prevention and Atherosclerotic Cardiovascular Disease Populations in United Kingdom
23/07/2021	A risk prediction model to predict incident heart failure (RiskHF): derivation and validation cohort study
23/07/2021	Identifying the clinical risks associated with COVID-19 in patients with congenital heart disease and associated co-morbidities
30/07/2021	Incretin-based drugs and the incidence of prostate cancer among patients with type 2 diabetes
30/07/2021	Event Rates and Risk factors for Cardiovascular Events in a United Kingdom Population with Hypertension
30/07/2021	Determining treatment pathways, healthcare resource usage, and associated costs of patients with Myasthenia Gravis in England
03/08/2021	Differences in morbidity and mortality in men and women with chronic obstructive pulmonary disease and peripheral arterial disease
03/08/2021	Epidemiology and healthcare resource utilisation associated with Duchenne muscular dystrophy
06/08/2021	Concomitant use of biphasic insulin aspart and glucagon-like peptide-1 receptor agonist compared to modern basal insulin combined with glucagon-like peptide-1 receptor agonist: effect on glycaemic control in type 2 diabetes patients
10/08/2021	Respiratory infection related cardiovascular disease: a prognostic modelling and causal inference study
12/08/2021	Incidence and prevalence of obesity, pre-diabetes, type 1 and 2 diabetes and complications and risk factors in people younger than 40 years in the UK.
12/08/2021	Assessing the clinical and economic burden among patients with Clostridium Difficile Infection and recurrent Clostridium Difficile Infections: A real-world evidence study
17/08/2021	The Impact of COVID-19 on care for UK patients with chronic obstructive pulmonary disease (COPD) and patients with asthma
20/08/2021	Feasibility study exploring trial population eligibility criteria and occurrence of outcomes to inform CV trial programme
27/08/2021	Parkinson's Disease in minority ethnic groups: understanding phenotypical traits and differences in outcomes to inform pathways of care