Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Date of Approval Sort ascending Title
30/06/2023 Investigating the epidemiology of peripheral nerve injury (PNI) and the prescription pattern of medication for PNI patients in UK: a longitudinal observational study
30/06/2023 Comparative effectiveness of glucagon like peptide 1 receptor agonists versus sodium-glucose co-transporter-2 inhibitors and dipeptidyl peptidase-4 inhibitors on hemoglobin A1C and body weight among people with type-2 diabetes and chronic kidney disease
29/06/2023 Prognosis and healthcare costs of musculoskeletal pain in children and adolescents in primary care
27/06/2023 Diagnostic pathways and healthcare resource utilisation of polycystic ovary syndrome patients in the United Kingdom
27/06/2023 Development, external validation and health economic evaluation of primary care diagnostic prediction models for upper gastro-intestinal cancers
27/06/2023 Treatment pathway for patients with open angle glaucoma: a descriptive study
27/06/2023 Characteristics and the economic burden of COVID-19 associated bacterial, viral and fungal infections in the general population in England
27/06/2023 Quantifying the risks of deprescribing of long-term cardiovascular medicines in people with limited life expectancy
23/06/2023 Infectious disease mortality among people with severe mental illness: Retrospective analysis of a national representative sample
20/06/2023 Comparative safety of prescription opioids and prediction of opioid-related adverse events in patients with non-cancer pain
19/06/2023 Repeat measures of anthropometry in patients with obesity to inform a model-based cost-effectiveness analysis for the treatment of obesity
19/06/2023 Epidemiology, treatment patterns, and healthcare resource utilization of patients with Essential Tremor: A retrospective cohort analysis in the United Kingdom
19/06/2023 A population-based assessment of drug-drug interactions with direct oral anticoagulants and the risk of major bleeding among patients with non-valvular atrial fibrillation
19/06/2023 Inadequate achievement in haemoglobin A1c and weight targets in adults with type 2 diabetes on once weekly glucagon-like peptide-1 receptor agonists therapy: a multi-variate analysis of UK primary care data
19/06/2023 Measuring Primary Care Resource Utilisation in England with Clinical Practice Research Datalink (CPRD) Aurum
19/06/2023 Using Real World Data to describing the burden of care, healthcare resource usage, and disease progression of patients diagnosed with rare ataxias in England & Wales
16/06/2023 The association between comorbid mental health conditions and risk of exacerbations and mortality among patients with chronic obstructive pulmonary disease
16/06/2023 Sex-specific differences in cardiovascular risk factors, risk factor management, treatment compliance and major cardiovascular outcomes in the peripheral arterial disease population
14/06/2023 DynAIRx (Dynamic Artificial Intelligence for Prescriptions): AIs (Artificial Intelligence) for dynamic prescribing optimisation and care integration in multimorbidity
13/06/2023 Use of leukotriene receptor antagonists (LTRAs) among patients with asthma in the UK primary care: a drug utilisation study