Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
21/07/2023	The efficacy and safety of concomitant treatment with valsartan and indapamide in patients with essential arterial hypertension: Outcomes in real world practice
20/07/2023	Comparing Symbicort with inhaled corticosteroid only in asthmatic adults and adolescents
18/07/2023	Understanding trajectories of healthcare use and costs over the multimorbidity journey: a longitudinal study
18/07/2023	Factors associated with referral to pulmonary rehabilitation and palliative care services in people with diagnosis of idiopathic pulmonary fibrosis
17/07/2023	Change in haematocrit after institution of sodium-glucose co-transporter 2 inhibitors in patients with type 2 diabetes and its relationship with cardiorenal outcomes
17/07/2023	Describing the association between ursodeoxycholic acid adherence and positive COVID-19 diagnosis in primary care in the United Kingdom
11/07/2023	Monitoring safety of Spikevax in pregnancy: an observational study using routinely collected health data in five European countries.
11/07/2023	Pharmacological treatments during pregnancy associated with the risk of developing short and long-term pregnancy outcomes: signal detection
11/07/2023	Evaluating the risk of disability progression, frailty, macrovascular events, and mortality in individuals with multiple sclerosis in England: a population-based retrospective cohort study
10/07/2023	Associations of SGLT2 inhibitors and GLP1 receptor agonists with incident dementia: a population-based cohort study
07/07/2023	Risk prediction modelling for gestational diabetes
07/07/2023	Levothyroxine and the risk of arrhythmias among patients with mild subclinical hypothyroidism: a population-based cohort study
06/07/2023	Obstructive sleep apnoea syndrome and future risk of dementia
04/07/2023	Antidiabetic drug utilisation after COVID-19 infection amongst patients with diabetes mellitus type 2: a retrospective cohort study from the UK
04/07/2023	Mental health of mothers of children with special educational needs or disabilities (SEND) in the UK before and during the COVID-19 pandemic.
04/07/2023	Diabetes and related complications in Autism Spectrum Disorder compared to general population controls
03/07/2023	Does the maternal GP check at six weeks postpartum play a role in improving outcomes for women with epilepsy?
30/06/2023	Comparative effectiveness of glucagon like peptide 1 receptor agonists versus sodium-glucose co-transporter-2 inhibitors and dipeptidyl peptidase-4 inhibitors on hemoglobin A1C and body weight among people with type-2 diabetes and chronic kidney disease
30/06/2023	Investigating the epidemiology of peripheral nerve injury (PNI) and the prescription pattern of medication for PNI patients in UK: a longitudinal observational study
29/06/2023	Prognosis and healthcare costs of musculoskeletal pain in children and adolescents in primary care