TY - JOUR KW - Administration, Inhalation KW - Adrenal Cortex Hormones/therapeutic use KW - Adrenergic beta-2 Receptor Agonists/adverse effects KW - Adult KW - Bronchodilator Agents/adverse effects KW - Cohort Studies KW - Drug Therapy, Combination KW - Formoterol Fumarate/adverse effects KW - Humans KW - Muscarinic Antagonists/adverse effects KW - *Myocardial Infarction/chemically induced/diagnosis/epidemiology KW - *Pulmonary Disease, Chronic Obstructive/diagnosis/drug therapy/epidemiology KW - Risk Assessment KW - *Stroke/diagnosis/epidemiology KW - Tiotropium Bromide/adverse effects KW - Lama KW - United Kingdom KW - aclidinium KW - Acute myocardial infarction KW - Stroke AU - C. Rebordosa AU - E. Plana AU - A. Rubino AU - J. Aguado AU - D. Martinez AU - A. Lei AU - S. Daoud AU - N. Saigi-Morgui AU - S. Perez-Gutthann AU - E. Rivero-Ferrer AD - Department of Epidemiology and Risk Management, RTI Health Solutions, Barcelona, Spain. Department of Biometrics, RTI Health Solutions, Barcelona, Spain. Epidemiology, Respiratory and Immunology, AstraZeneca, Cambridge, UK. Patient Safety Biopharma, AstraZeneca, Barcelona, Spain. BioPharmaceuticals Research and Development, Late-Stage Development Respiratory and Immunology, AstraZeneca, Gaithersburg, MD, USA. AN - 35941901 BT - Int J Chron Obstruct Pulmon Dis C2 - PMC9356604 DO - 10.2147/copd.s363997 DP - NLM ET - 2022/08/10 LA - eng N1 - 1178-2005 Rebordosa, Cristina Orcid: 0000-0002-8064-5997 Plana, Estel Orcid: 0000-0001-8675-7503 Rubino, Annalisa Aguado, Jaume Orcid: 0000-0002-9575-0212 Martinez, David Orcid: 0000-0001-7001-7674 Lei, Alejhandra Daoud, Sami Saigi-Morgui, Nuria Orcid: 0000-0003-2503-1818 Perez-Gutthann, Susana Orcid: 0000-0001-5798-3691 Rivero-Ferrer, Elena Orcid: 0000-0001-5093-2445 Journal Article Int J Chron Obstruct Pulmon Dis. 2022 Aug 2;17:1715-1733. doi: 10.2147/COPD.S363997. eCollection 2022. PY - 2022 SN - 1176-9106 (Print)1176-9106 SP - 1715 EP - 1733 T2 - Int J Chron Obstruct Pulmon Dis TI - Risk Assessment of Acute Myocardial Infarction and Stroke Associated with Long-Acting Muscarinic Antagonists, Alone or in Combination, versus Long-Acting beta2-Agonists VL - 17 ER -