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2020
R. Flynn, Hedenmalm, K., Murray-Thomas, T., Pacurariu, A., Arlett, P., Shepherd, H., Myles, P., and Kurz, X., Ability of primary care health databases to assess medicinal products discussed by the European Union Pharmacovigilance Risk Assessment Committee, Clin Pharmacol Ther, 2020.
G. Simoneau, Moodie, E. E. M., Azoulay, L., and Platt, R. W., Adaptive Treatment Strategies with Survival Outcomes: An Application to the Treatment of Type 2 Diabetes using a Large Observational Database, Am J Epidemiol, 2020.
S. Chowienczyk, Price, S., and Hamilton, W., Changes in the presenting symptoms of lung cancer from 2000-2017: a serial cross-sectional study of observational records in UK primary care, Br J Gen Pract, 2020.
S. Wilkinson, Williamson, E., Pokrajac, A., Fogarty, D., Stirnadel-Farrant, H., Smeeth, L., Douglas, I. J., and Tomlinson, L. A., Comparative effects of sulfonylureas, DPP4is and SGLT2 inhibitors added to metformin monotherapy: a propensity-score matched cohort study in UK primary care, Diabetes Obes Metab, 2020.
S. Borghs, Byram, L., Chan, J., Dedeken, P., Logan, J., Kiri, V., Noack-Rink, M., Patsalos, P. N., and Thieffry, S., Comparing healthcare cost associated with the use of enzyme-inducing and non-enzyme active antiepileptic drugs in elderly patients with epilepsy in the UK: a long-term retrospective, matched cohort study, BMC Neurol, vol. 20, p. 7, 2020.
J. R. Ayala Solares, Raimondi, F. E. Diletta, Zhu, Y., Rahimian, F., Canoy, D., Tran, J., Gomes, A. C. Pinho, Payberah, A. H., Zottoli, M., Nazarzadeh, M., Conrad, N., Rahimi, K., and Salimi-Khorshidi, G., Deep learning for electronic health records: A comparative review of multiple deep neural architectures, J Biomed Inform, vol. 101, p. 103337, 2020.
R. A. Payne, Mendonca, S. C., Elliott, M. N., Saunders, C. L., Edwards, D. A., Marshall, M., and Roland, M., Development and validation of the Cambridge Multimorbidity Score, Cmaj, vol. 192, pp. E107-e114, 2020.
M. D. Danese, Pemberton-Ross, P., Catterick, D., and Villa, G., Estimation of the increased risk associated with recurrent events or polyvascular atherosclerotic cardiovascular disease in the United Kingdom, Eur J Prev Cardiol, p. 2047487319899212, 2020.
R. Mathur, Palla, L., Farmer, R. E., Chaturvedi, N., and Smeeth, L., Ethnic differences in the severity and clinical management of type 2 diabetes at time of diagnosis: A cohort study in the UK Clinical Practice Research Datalink, Diabetes Res Clin Pract, vol. 160, p. 108006, 2020.
C. Martinez, Wallenhorst, C., Rietbrock, S., and Freedman, B., Ischemic Stroke and Transient Ischemic Attack Risk Following Vitamin K Antagonist Cessation in Newly Diagnosed Atrial Fibrillation: A Cohort Study, J Am Heart Assoc, vol. 9, p. e014376, 2020.
H. J. L. Heerspink, Karasik, A., Thuresson, M., Melzer-Cohen, C., Chodick, G., Khunti, K., Wilding, J. P. H., Rodriguez, L. A. Garcia, Cea-Soriano, L., Kohsaka, S., Nicolucci, A., Lucisano, G., Lin, F. J., Wang, C. Y., Wittbrodt, E., Fenici, P., and Kosiborod, M., Kidney outcomes associated with use of SGLT2 inhibitors in real-world clinical practice (CVD-REAL 3): a multinational observational cohort study, Lancet Diabetes Endocrinol, vol. 8, pp. 27-35, 2020.
D. Alarkawi, Ali, M. S., Bliuc, D., Pallares, N., Tebe, C., Elhussein, L., Caskey, F. J., Arden, N. K., Ben-Shlomo, Y., Abrahamsen, B., Diez-Perez, A., Pascual, J., Perez-Saez, M. J., Center, J. R., Judge, A., Cooper, C., Javaid, M. K., and Prieto-Alhambra, D., Oral bisphosphonate use and all-cause mortality in patients with moderate-severe (grade 3B-5D) chronic kidney disease: a population-based cohort study, J Bone Miner Res, 2020.
A. Gadoud, Kane, E., Oliver, S. E., Johnson, M. J., Macleod, U., and Allgar, V., Palliative care for non-cancer conditions in primary care: a time trend analysis in the UK (2009-2014), BMJ Support Palliat Care, 2020.
C. Martinez, Katholing, A., Wallenhorst, C., and Cohen, A. T., Prediction of significant bleeding during vitamin K antagonist treatment for venous thromboembolism in outpatients, Br J Haematol, 2020.
A. Price, Ford, T., Janssens, A., Williams, A. J., and Newlove-Delgado, T., Regional analysis of UK primary care prescribing and adult service referrals for young people with attention-deficit hyperactivity disorder, BJPsych Open, vol. 6, p. e7, 2020.
T. Burkard, Rauch, M., Spoendlin, J., Prieto-Alhambra, D., Jick, S. S., and Meier, C. R., Risk of hand osteoarthritis in new users of hormone replacement therapy: A nested case-control analysis, Maturitas, vol. 132, pp. 17-23, 2020.
H. Forbes, Douglas, I., Finn, A., Breuer, J., Bhaskaran, K., Smeeth, L., Packer, S., Langan, S. M., Mansfield, K. E., Marlow, R., Whitaker, H., and Warren-Gash, C., Risk of herpes zoster after exposure to varicella to explore the exogenous boosting hypothesis: self controlled case series study using UK electronic healthcare data, Bmj, vol. 368, p. l6987, 2020.
D. J. Grint, McDonald, H. I., Walker, J. L., Amirthalingam, G., Andrews, N., and Thomas, S., Safety of inadvertent administration of live zoster vaccine to immunosuppressed individuals in a UK-based observational cohort analysis, BMJ Open, vol. 10, p. e034886, 2020.
R. Denholm, van der Werf, E. T., and Hay, A. D., Use of antibiotics and asthma medication for acute lower respiratory tract infections in people with and without asthma: retrospective cohort study, Respir Res, vol. 21, p. 4, 2020.
2019
C. A. Lawson, Zaccardi, F., Squire, I., Ling, S., Davies, M. J., Lam, C. S. P., Mamas, M. A., Khunti, K., and Kadam, U. T., 20-year trends in cause-specific heart failure outcomes by sex, socioeconomic status, and place of diagnosis: a population-based study, Lancet Public Health, vol. 4, pp. e406-e420, 2019.
A. M. Gallagher, Dedman, D., Padmanabhan, S., Leufkens, H. G. M., and de Vries, F., The accuracy of date of death recording in the Clinical Practice Research Datalink GOLD database in England compared with the Office for National Statistics death registrations, Pharmacoepidemiol Drug Saf, 2019.
C. Becker, Jick, S. S., and Meier, C. R., ACE inhibitor use and risk of cataract: a case-control analysis, Br J Ophthalmol, 2019.
J. Watson, Salisbury, C., Whiting, P., Banks, J., Pyne, Y., and Hamilton, W., Added value and cascade effects of inflammatory marker tests in UK primary care: a cohort study from the Clinical Practice Research Datalink, Br J Gen Pract, vol. 69, pp. e470-e478, 2019.
K. D. Johnson, Lu, X., and Zhang, D., Adherence to hepatitis A and hepatitis B multi-dose vaccination schedules among adults in the United Kingdom: a retrospective cohort study, BMC Public Health, vol. 19, p. 404, 2019.
R. L. Tannen, Barnhart, K. T., and Rubin, J. C., Advantages of large medical record database for outcomes research: Insights into post-menopausal hormone therapy, Learn Health Syst, vol. 3, p. e10193, 2019.
M. Rafiq, Hayward, A., Warren-Gash, C., Denaxas, S., Gonzalez-Izquierdo, A., Lyratzopoulos, G., and Thomas, S., Allergic disease, corticosteroid use and risk of Hodgkin's lymphoma: A UK Nationwide case-control study, J Allergy Clin Immunol, 2019.
A. J. Klil-Drori, Santella, C., Tascilar, K., Yin, H., Aprikian, A., and Azoulay, L., Androgen Deprivation Therapy for Prostate Cancer and the Risk of Rheumatoid Arthritis: A Population-Based Cohort Study, Drug Saf, 2019.
M. Nowakowska, Van Staa, T., Molter, A., Ashcroft, D. M., Tsang, J. Y., White, A., Welfare, W., and Palin, V., Antibiotic choice in UK general practice: rates and drivers of potentially inappropriate antibiotic prescribing, J Antimicrob Chemother, 2019.
O. van Hecke, Fuller, A., Bankhead, C., Jenkins-Jones, S., Francis, N., Moore, M., Butler, C., and Wang, K., Antibiotic exposure and 'response failure' for subsequent respiratory tract infections: an observational cohort study of UK preschool children in primary care, Br J Gen Pract, vol. 69, pp. e638-e646, 2019.
M. Gharbi, Drysdale, J. H., Lishman, H., Goudie, R., Molokhia, M., Johnson, A. P., Holmes, A. H., and Aylin, P., Antibiotic management of urinary tract infection in elderly patients in primary care and its association with bloodstream infections and all cause mortality: population based cohort study, Bmj, vol. 364, p. l525, 2019.
P. Rockenschaub, Hayward, A., and Shallcross, L., Antibiotic prescribing before and after the diagnosis of comorbidity: a cohort study using primary care electronic health records, Clin Infect Dis, 2019.
V. Palin, Molter, A., Belmonte, M., Ashcroft, D. M., White, A., Welfare, W., and Van Staa, T., Antibiotic prescribing for common infections in UK general practice: variability and drivers, J Antimicrob Chemother, 2019.
H. Ahmed, Farewell, D., Jones, H. M., Francis, N. A., Paranjothy, S., and Butler, C. C., Antibiotic prophylaxis and clinical outcomes among older adults with recurrent urinary tract infection: cohort study, Age Ageing, vol. 48, pp. 228-234, 2019.
N. S. Nagra, Robinson, D. E., Douglas, I., Delmestri, A., Dakin, S. G., Snelling, S. J. B., Carr, A. J., and Prieto-Alhambra, D., Antibiotic treatment and flares of rheumatoid arthritis: a self-controlled case series study analysis using CPRD GOLD, Sci Rep, vol. 9, p. 8941, 2019.
C. Hopkins, Williamson, E., Morris, S., Clarke, C. S., Thomas, M., Evans, H., Little, P., Lund, V. J., Blackshaw, H., Schilder, A., Philpott, C., Carpenter, J., and Denaxas, S., Antibiotic usage in chronic rhinosinusitis: analysis of national primary care electronic health records, Rhinology, 2019.
A. A. Sultan, Mallen, C., Muller, S., Hider, S., Scott, I., Helliwell, T., and Hall, L. J., Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study, BMC Med, vol. 17, p. 154, 2019.
F. S. Troelsen and Jick, S., Antibiotic Use in Childhood and Adolescence and Risk of Inflammatory Bowel Disease: A Case-Control Study in the UK Clinical Practice Research Datalink, Inflamm Bowel Dis, 2019.
L. A. Garcia Rodriguez, Martin-Perez, M., Vora, P., Roberts, L., Balabanova, Y., Brobert, G., Fatoba, S., Suzart-Woischnik, K., Schaefer, B., and Ruigomez, A., Appropriateness of initial dose of non-vitamin K antagonist oral anticoagulants in patients with non-valvular atrial fibrillation in the UK, BMJ Open, vol. 9, p. e031341, 2019.
R. Hoile, Tabet, N., Smith, H., Bremner, S., Cassell, J., and Ford, E., Are symptoms of insomnia in primary care associated with subsequent onset of dementia? A matched retrospective case-control study, Aging Ment Health, pp. 1-6, 2019.
J. L. Walker, Zhao, H., Dabrera, G., Andrews, N., Thomas, S. L., Tsang, C., Ellis, J., Donati, M., and Pebody, R. G., Assessment of Effectiveness of Seasonal Influenza Vaccination During Pregnancy in Preventing Influenza Infection in Infants in England, 2013-2014 and 2014-2015, J Infect Dis, 2019.
P. Kasteridis, Ride, J., Gutacker, N., Aylott, L., Dare, C., Doran, T., Gilbody, S., Goddard, M., Gravelle, H., Kendrick, T., Mason, A., Rice, N., Siddiqi, N., Williams, R., and Jacobs, R., Association Between Antipsychotic Polypharmacy and Outcomes for People With Serious Mental Illness in England, Psychiatr Serv, p. appips201800504, 2019.
S. H. Landis, Pimenta, J. M., Yang, S., Compton, C., Barnes, N., and Brusselle, G., Association between blood eosinophils and acute exacerbation of COPD risk in patients with COPD in primary care, Respiratory Medicine, vol. 1, 2019.
J. Vavanikunnel, Charlier, S., Becker, C., Schneider, C., Jick, S. S., Meier, C. R., and Meier, C., Association between glycemic control and risk of fracture in diabetic patients: A nested case-control study, J Clin Endocrinol Metab, 2019.
G. Nakafero, Grainge, M. J., Myles, P. R., Mallen, C. D., Zhang, W., Doherty, M., Nguyen-Van-Tam, J. S., and Abhishek, A., Association between inactivated influenza vaccine and primary care consultations for autoimmune rheumatic disease flares: a self-controlled case series study using data from the Clinical Practice Research Datalink, Ann Rheum Dis, 2019.
Y. M. F. Andersen, Egeberg, A., Ban, L., Gran, S., Williams, H. C., Francis, N. A., Knop, F. K., Gislason, G. H., Skov, L., and Thyssen, J. P., Association Between Topical Corticosteroid Use and Type 2 Diabetes in Two European Population-Based Adult Cohorts, Diabetes Care, vol. 42, pp. 1095-1103, 2019.
R. Williams, Kothny, W., Serban, C., Lopez-Leon, S., de Vries, F., and Schlienger, R., Association between vildagliptin and risk of angioedema, foot ulcers, skin lesions, hepatic toxicity, and serious infections in patients with type 2 diabetes mellitus: A European multidatabase, noninterventional, postauthorization safety study, Endocrinol Diabetes Metab, vol. 2, p. e00084, 2019.
F. Montastruc, Nie, R., Loo, S., Rej, S., Dell'Aniello, S., Micallef, J., Suissa, S., and Renoux, C., Association of Aripiprazole With the Risk for Psychiatric Hospitalization, Self-harm, or Suicide, JAMA Psychiatry, 2019.
S. Abtahi, Burden, A. M., Geusens, P., van den Bergh, J. P., Van Staa, T., and de Vries, F., The Association of Oral Bisphosphonate Use With Mortality Risk Following a Major Osteoporotic Fracture in the United Kingdom: Population-Based Cohort Study, J Am Med Dir Assoc, 2019.
A. Root, Brown, J. P., Forbes, H. J., Bhaskaran, K., Hayes, J., Smeeth, L., and Douglas, I. J., Association of Relative Age in the School Year With Diagnosis of Intellectual Disability, Attention-Deficit/Hyperactivity Disorder, and Depression, JAMA Pediatr, 2019.
K. E. Lowe, Mansfield, K. E., Delmestri, A., Smeeth, L., Roberts, A., Abuabara, K., Prieto-Alhambra, D., and Langan, S. M., Atopic eczema and fracture risk in adults: A population-based cohort study, J Allergy Clin Immunol, 2019.