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2020
R. Flynn, Hedenmalm, K., Murray-Thomas, T., Pacurariu, A., Arlett, P., Shepherd, H., Myles, P., and Kurz, X., Ability of primary care health databases to assess medicinal products discussed by the European Union Pharmacovigilance Risk Assessment Committee, Clin Pharmacol Ther, 2020.
G. Simoneau, Moodie, E. E. M., Azoulay, L., and Platt, R. W., Adaptive Treatment Strategies with Survival Outcomes: An Application to the Treatment of Type 2 Diabetes using a Large Observational Database, Am J Epidemiol, 2020.
F. Khosrow-Khavar, Filion, K. B., Bouganim, N., Suissa, S., and Azoulay, L., Aromatase Inhibitors and the Risk of Cardiovascular Outcomes in Women With Breast Cancer: A Population-Based Cohort Study, Circulation, vol. 141, pp. 549-559, 2020.
H. Fan, Gilbert, R., O'Callaghan, F., and Li, L., Associations between macrolide antibiotics prescribing during pregnancy and adverse child outcomes in the UK: population based cohort study, Bmj, vol. 368, p. m331, 2020.
F. Giorgianni, Ernst, P., Dell'Aniello, S., Suissa, S., and Renoux, C., Beta 2 agonists and the incidence of Parkinson's disease, Am J Epidemiol, 2020.
I. Matthews, Duong, M., Parsons, V. L., Nozad, B., Qizilbash, N., Patel, Y., and Guimicheva, B., Burden of disease from shingles and post-herpetic neuralgia in the over 80 year olds in the UK, PLoS One, vol. 15, p. e0229224, 2020.
S. Chowienczyk, Price, S., and Hamilton, W., Changes in the presenting symptoms of lung cancer from 2000-2017: a serial cross-sectional study of observational records in UK primary care, Br J Gen Pract, 2020.
S. Wilkinson, Williamson, E., Pokrajac, A., Fogarty, D., Stirnadel-Farrant, H., Smeeth, L., Douglas, I. J., and Tomlinson, L. A., Comparative effects of sulfonylureas, DPP4is and SGLT2 inhibitors added to metformin monotherapy: a propensity-score matched cohort study in UK primary care, Diabetes Obes Metab, 2020.
S. Borghs, Byram, L., Chan, J., Dedeken, P., Logan, J., Kiri, V., Noack-Rink, M., Patsalos, P. N., and Thieffry, S., Comparing healthcare cost associated with the use of enzyme-inducing and non-enzyme active antiepileptic drugs in elderly patients with epilepsy in the UK: a long-term retrospective, matched cohort study, BMC Neurol, vol. 20, p. 7, 2020.
P. Rockenschaub, Nguyen, V., Aldridge, R. W., Acosta, D., Garcia-Gomez, J. M., and Saez, C., Data-driven discovery of changes in clinical code usage over time: a case-study on changes in cardiovascular disease recording in two English electronic health records databases (2001-2015), BMJ Open, vol. 10, p. e034396, 2020.
J. R. Ayala Solares, Raimondi, F. E. Diletta, Zhu, Y., Rahimian, F., Canoy, D., Tran, J., Gomes, A. C. Pinho, Payberah, A. H., Zottoli, M., Nazarzadeh, M., Conrad, N., Rahimi, K., and Salimi-Khorshidi, G., Deep learning for electronic health records: A comparative review of multiple deep neural architectures, J Biomed Inform, vol. 101, p. 103337, 2020.
R. A. Payne, Mendonca, S. C., Elliott, M. N., Saunders, C. L., Edwards, D. A., Marshall, M., and Roland, M., Development and validation of the Cambridge Multimorbidity Score, Cmaj, vol. 192, pp. E107-e114, 2020.
C. J. D. Threapleton, Kimpton, J. E., Carey, I. M., DeWilde, S., Cook, D. G., Harris, T., and Baker, E. H., Development of a structured clinical pharmacology review for specialist support for management of complex polypharmacy in primary care, Br J Clin Pharmacol, 2020.
M. D. Danese, Pemberton-Ross, P., Catterick, D., and Villa, G., Estimation of the increased risk associated with recurrent events or polyvascular atherosclerotic cardiovascular disease in the United Kingdom, Eur J Prev Cardiol, p. 2047487319899212, 2020.
R. Mathur, Palla, L., Farmer, R. E., Chaturvedi, N., and Smeeth, L., Ethnic differences in the severity and clinical management of type 2 diabetes at time of diagnosis: A cohort study in the UK Clinical Practice Research Datalink, Diabetes Res Clin Pract, vol. 160, p. 108006, 2020.
S. Jarvis, Parslow, R. C., Hewitt, C., Mitchell, S., and Fraser, L. K., GPs' role in caring for children and young people with life-limiting conditions: a retrospective cohort study, Br J Gen Pract, 2020.
R. Persson, Lee, S., M. Yood, U., Mc, C. M. Wagner, Minton, N., Niemcryk, S., Lindholm, A., Evans, A. M., and Jick, S. S., Infections in patients diagnosed with multiple sclerosis: A multi-database study, Mult Scler Relat Disord, vol. 41, p. 101982, 2020.
L. E. Clarson, Bajpai, R., Whittle, R., Belcher, J., A. Sultan, A., Kwok, C. S., Welsh, V., Mamas, M., and Mallen, C. D., Interstitial lung disease is a risk factor for ischaemic heart disease and myocardial infarction, Heart, 2020.
C. Martinez, Wallenhorst, C., Rietbrock, S., and Freedman, B., Ischemic Stroke and Transient Ischemic Attack Risk Following Vitamin K Antagonist Cessation in Newly Diagnosed Atrial Fibrillation: A Cohort Study, J Am Heart Assoc, vol. 9, p. e014376, 2020.
H. J. L. Heerspink, Karasik, A., Thuresson, M., Melzer-Cohen, C., Chodick, G., Khunti, K., Wilding, J. P. H., Rodriguez, L. A. Garcia, Cea-Soriano, L., Kohsaka, S., Nicolucci, A., Lucisano, G., Lin, F. J., Wang, C. Y., Wittbrodt, E., Fenici, P., and Kosiborod, M., Kidney outcomes associated with use of SGLT2 inhibitors in real-world clinical practice (CVD-REAL 3): a multinational observational cohort study, Lancet Diabetes Endocrinol, vol. 8, pp. 27-35, 2020.
C. J. Sammon, Leahy, T. P., and Ramagopalan, S., Nonindependence of patient data in the clinical practice research datalink: a case study in atrial fibrillation patients, J Comp Eff Res, 2020.
D. Alarkawi, Ali, M. S., Bliuc, D., Pallares, N., Tebe, C., Elhussein, L., Caskey, F. J., Arden, N. K., Ben-Shlomo, Y., Abrahamsen, B., Diez-Perez, A., Pascual, J., Perez-Saez, M. J., Center, J. R., Judge, A., Cooper, C., Javaid, M. K., and Prieto-Alhambra, D., Oral bisphosphonate use and all-cause mortality in patients with moderate-severe (grade 3B-5D) chronic kidney disease: a population-based cohort study, J Bone Miner Res, 2020.
A. Gadoud, Kane, E., Oliver, S. E., Johnson, M. J., Macleod, U., and Allgar, V., Palliative care for non-cancer conditions in primary care: a time trend analysis in the UK (2009-2014), BMJ Support Palliat Care, 2020.
M. M. Loiacono, Mahmud, S. M., Chit, A., van Aalst, R., Kwong, J. C., Mitsakakis, N., Skinner, L., Thommes, E., Bricout, H., and Grootendorst, P., Patient and practice level factors associated with seasonal influenza vaccine uptake among at-risk adults in England, 2011 to 2016: An age-stratified retrospective cohort study, Vaccine X, vol. 4, p. 100054, 2020.
C. Martinez, Katholing, A., Wallenhorst, C., and Cohen, A. T., Prediction of significant bleeding during vitamin K antagonist treatment for venous thromboembolism in outpatients, Br J Haematol, 2020.
Y. Chen, Hayward, R., Chew-Graham, C. A., Hubbard, R., Croft, P., Sims, K., and Jordan, K. P., Prognostic value of first-recorded breathlessness for future chronic respiratory and heart disease a cohort study using a UK national primary care database, Br J Gen Pract, 2020.
A. Price, Ford, T., Janssens, A., Williams, A. J., and Newlove-Delgado, T., Regional analysis of UK primary care prescribing and adult service referrals for young people with attention-deficit hyperactivity disorder, BJPsych Open, vol. 6, p. e7, 2020.
T. Burkard, Rauch, M., Spoendlin, J., Prieto-Alhambra, D., Jick, S. S., and Meier, C. R., Risk of hand osteoarthritis in new users of hormone replacement therapy: A nested case-control analysis, Maturitas, vol. 132, pp. 17-23, 2020.
H. Forbes, Douglas, I., Finn, A., Breuer, J., Bhaskaran, K., Smeeth, L., Packer, S., Langan, S. M., Mansfield, K. E., Marlow, R., Whitaker, H., and Warren-Gash, C., Risk of herpes zoster after exposure to varicella to explore the exogenous boosting hypothesis: self controlled case series study using UK electronic healthcare data, Bmj, vol. 368, p. l6987, 2020.
Y. Zhang, Souverein, P. C., Gardarsdottir, H., van den Ham, H. A., van der Zee, A. H. Maitlan, and de Boer, A., Risk of major bleeding among users of direct oral anticoagulants combined with interacting drugs: A population-based nested case-control study, Br J Clin Pharmacol, 2020.
D. J. Grint, McDonald, H. I., Walker, J. L., Amirthalingam, G., Andrews, N., and Thomas, S., Safety of inadvertent administration of live zoster vaccine to immunosuppressed individuals in a UK-based observational cohort analysis, BMJ Open, vol. 10, p. e034886, 2020.
M. C. Gulliford, Sun, X., Charlton, J., Winter, J. R., Bunce, C., Boiko, O., Fox, R., Little, P., Moore, M., Hay, A. D., and Ashworth, M., Serious bacterial infections and antibiotic prescribing in primary care: cohort study using electronic health records in the UK, BMJ Open, vol. 10, p. e036975, 2020.
A. Sarmanova, Doherty, M., Kuo, C., Wei, J., Abhishek, A., Mallen, C., Zeng, C., Wang, Y., Lei, G., and Zhang, W., Statin use and risk of joint replacement due to osteoarthritis and rheumatoid arthritis: a propensity-score matched longitudinal cohort study, Rheumatology (Oxford), 2020.
D. C. Gibbons, Aggarwal, B., Fairburn-Beech, J., Hinds, D., Fletcher, M., Bosnic-Anticevich, S., and Price, D., Treatment patterns among non-active users of maintenance asthma medication in the United Kingdom: a retrospective cohort study in the Clinical Practice Research Datalink, J Asthma, pp. 1-12, 2020.
R. Denholm, van der Werf, E. T., and Hay, A. D., Use of antibiotics and asthma medication for acute lower respiratory tract infections in people with and without asthma: retrospective cohort study, Respir Res, vol. 21, p. 4, 2020.
N. M. Davies, Taylor, A. E., Taylor, G. M., Itani, T., Jones, T., Martin, R. M., Munafo, M. R., Windmeijer, F., and Thomas, K. H., Varenicline versus nicotine replacement therapy for long-term smoking cessation: an observational study using the Clinical Practice Research Datalink, Health Technol Assess, vol. 24, pp. 1-46, 2020.
2019
C. A. Lawson, Zaccardi, F., Squire, I., Ling, S., Davies, M. J., Lam, C. S. P., Mamas, M. A., Khunti, K., and Kadam, U. T., 20-year trends in cause-specific heart failure outcomes by sex, socioeconomic status, and place of diagnosis: a population-based study, Lancet Public Health, vol. 4, pp. e406-e420, 2019.
A. M. Gallagher, Dedman, D., Padmanabhan, S., Leufkens, H. G. M., and de Vries, F., The accuracy of date of death recording in the Clinical Practice Research Datalink GOLD database in England compared with the Office for National Statistics death registrations, Pharmacoepidemiol Drug Saf, 2019.
C. Becker, Jick, S. S., and Meier, C. R., ACE inhibitor use and risk of cataract: a case-control analysis, Br J Ophthalmol, 2019.
J. Watson, Salisbury, C., Whiting, P., Banks, J., Pyne, Y., and Hamilton, W., Added value and cascade effects of inflammatory marker tests in UK primary care: a cohort study from the Clinical Practice Research Datalink, Br J Gen Pract, vol. 69, pp. e470-e478, 2019.
K. D. Johnson, Lu, X., and Zhang, D., Adherence to hepatitis A and hepatitis B multi-dose vaccination schedules among adults in the United Kingdom: a retrospective cohort study, BMC Public Health, vol. 19, p. 404, 2019.
R. L. Tannen, Barnhart, K. T., and Rubin, J. C., Advantages of large medical record database for outcomes research: Insights into post-menopausal hormone therapy, Learn Health Syst, vol. 3, p. e10193, 2019.
M. Rafiq, Hayward, A., Warren-Gash, C., Denaxas, S., Gonzalez-Izquierdo, A., Lyratzopoulos, G., and Thomas, S., Allergic disease, corticosteroid use and risk of Hodgkin's lymphoma: A UK Nationwide case-control study, J Allergy Clin Immunol, 2019.
A. J. Klil-Drori, Santella, C., Tascilar, K., Yin, H., Aprikian, A., and Azoulay, L., Androgen Deprivation Therapy for Prostate Cancer and the Risk of Rheumatoid Arthritis: A Population-Based Cohort Study, Drug Saf, 2019.
M. Nowakowska, Van Staa, T., Molter, A., Ashcroft, D. M., Tsang, J. Y., White, A., Welfare, W., and Palin, V., Antibiotic choice in UK general practice: rates and drivers of potentially inappropriate antibiotic prescribing, J Antimicrob Chemother, 2019.
O. van Hecke, Fuller, A., Bankhead, C., Jenkins-Jones, S., Francis, N., Moore, M., Butler, C., and Wang, K., Antibiotic exposure and 'response failure' for subsequent respiratory tract infections: an observational cohort study of UK preschool children in primary care, Br J Gen Pract, vol. 69, pp. e638-e646, 2019.
M. Gharbi, Drysdale, J. H., Lishman, H., Goudie, R., Molokhia, M., Johnson, A. P., Holmes, A. H., and Aylin, P., Antibiotic management of urinary tract infection in elderly patients in primary care and its association with bloodstream infections and all cause mortality: population based cohort study, Bmj, vol. 364, p. l525, 2019.
P. Rockenschaub, Hayward, A., and Shallcross, L., Antibiotic prescribing before and after the diagnosis of comorbidity: a cohort study using primary care electronic health records, Clin Infect Dis, 2019.
V. Palin, Molter, A., Belmonte, M., Ashcroft, D. M., White, A., Welfare, W., and Van Staa, T., Antibiotic prescribing for common infections in UK general practice: variability and drivers, J Antimicrob Chemother, 2019.
H. Ahmed, Farewell, D., Jones, H. M., Francis, N. A., Paranjothy, S., and Butler, C. C., Antibiotic prophylaxis and clinical outcomes among older adults with recurrent urinary tract infection: cohort study, Age Ageing, vol. 48, pp. 228-234, 2019.