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2021
S. M. Grandi, Filion, K. B., Hutcheon, J. A., Rosella, L. C., and Platt, R. W., Accounting for Repeat Pregnancies in Risk Prediction Models, Epidemiology, 2021.
F. S. Al-Hamed, Kouniaris, S., Tamimi, I., Lordkipanidzé, M., Madathil, S. A., Kezouh, A., Karp, I., Nicolau, B., and Tamimi, F., Acetylcholinesterase inhibitors and risk of bleeding and acute ischemic events in non-hypertensive Alzheimer's patients, Alzheimers Dement (N Y), vol. 7, p. e12184, 2021.
L. L. N. Husemoen, Mørch, L. S., Christensen, P. K., Hartvig, N. V., and Feher, M. D., All-Cause and Cardiovascular Mortality Among Insulin-Naïve People With Type 2 Diabetes Treated With Insulin Detemir or Glargine: A Cohort Study in the UK, Diabetes Ther, 2021.
A. Jaggi, Nazir, J., Fatoye, F., Quelen, C., Tu, X., Ali, M., Siddiqui, E., Covernton, P. J. O., Landeira, M., and Choudhury, N., Anticholinergic Burden and Associated Healthcare Resource Utilization in Older Adults with Overactive Bladder, Drugs Aging, 2021.
E. Rezel-Potts, Douiri, A., Chowienczyk, P. J., and Gulliford, M. C., Antihypertensive Medications and COVID-19 Diagnosis and Mortality: Population-based Case-Control Analysis in the United Kingdom, Br J Clin Pharmacol, 2021.
E. Rezel-Potts, L'Esperance, V., and Gullifiord, M., Antimicrobial stewardship during the COVID-19 epidemic: population-based cohort study and interrupted time series analysis in the United Kingdom, Br J Gen Pract, 2021.
L. M. Woods, Rachet, B., Morris, M., Bhaskaran, K., and Coleman, M. P., Are socio-economic inequalities in breast cancer survival explained by peri-diagnostic factors?, BMC Cancer, vol. 21, p. 485, 2021.
S. S. Zghebi, Mamas, M. A., Ashcroft, D. M., Rutter, M. K., VanMarwijk, H., Salisbury, C., Mallen, C. D., Chew-Graham, C. A., Qureshi, N., Weng, S. F., Holt, T., Buchan, I., Peek, N., Giles, S., Reeves, D., and Kontopantelis, E., Assessing the severity of cardiovascular disease in 213 088 patients with coronary heart disease: a retrospective cohort study, Open Heart, vol. 8, 2021.
R. Muzambi, Bhaskaran, K., Smeeth, L., Brayne, C., Chaturvedi, N., and Warren-Gash, C., Assessment of common infections and incident dementia using UK primary and secondary care data: a historical cohort study, Lancet Healthy Longev, vol. 2, pp. e426-e435, 2021.
M. Usman, Khunti, K., Davies, M. J., and Gillies, C. L., Association and relative importance of multiple risk factor control on cardiovascular disease, end-stage renal disease and mortality in people with type 2 diabetes: A population-based retrospective cohort study, Prim Care Diabetes, vol. 15, pp. 218-226, 2021.
J. Blackwell, Alexakis, C., Saxena, S., Creese, H., Bottle, A., Petersen, I., Hotopf, M., and Pollok, R. C. G., Association between antidepressant medication use and steroid dependency in patients with ulcerative colitis: a population-based study, BMJ Open Gastroenterol, vol. 8, 2021.
T. C. Chen, Knaggs, R. D., and Chen, L. C., Association between opioid-related deaths and persistent opioid prescribing in primary care in England: a nested case-control study, Br J Clin Pharmacol, 2021.
T. C. Chen, Knaggs, R. D., and Chen, L. C., Association between opioid-related deaths and prescribed opioid dose and psychotropic medicines in England: a case-crossover study, Br J Anaesth, 2021.
S. S. Johnston, Jamous, N., Mistry, S., Jain, S., Gangoli, G., Danker, W., Ammann, E., and Hampton, K., Association of In-Hospital Surgical Bleeding Events with Prolonged Hospital Length of Stay, Days Spent in Critical Care, Complications, and Mortality: A Retrospective Cohort Study Among Patients Undergoing Neoplasm-Directed Surgeries in English Hospitals, Clinicoecon Outcomes Res, vol. 13, pp. 19-29, 2021.
F. Hamilton, Arnold, D., and Payne, R., Association of prior lymphopenia with mortality in pneumonia: a cohort study in UK primary care, Br J Gen Pract, vol. 71, pp. e148-e156, 2021.
A. J. McKay, Gunn, L. H., Vamos, E. P., Valabhji, J., Molina, G., Molokhia, M., and Majeed, A., Associations between attainment of incentivised primary care diabetes indicators and mortality in an English cohort, Diabetes Res Clin Pract, vol. 174, p. 108746, 2021.
L. H. Gunn, McKay, A. J., Molokhia, M., Valabhji, J., Molina, G., Majeed, A., and Vamos, E. P., Associations between attainment of incentivised primary care indicators and emergency hospital admissions among type 2 diabetes patients: a population-based historical cohort study, J R Soc Med, p. 1410768211005109, 2021.
A. J. McKay, Gunn, L. H., Sathish, T., Vamos, E., Nugawela, M., Majeed, A., Molina, G., and Sivaprasad, S., Associations between attainment of incentivised primary care indicators and incident diabetic retinopathy in England: a population-based historical cohort study, BMC Med, vol. 19, p. 93, 2021.
H. Carreira, Williams, R., Funston, G., Stanway, S., and Bhaskaran, K., Associations between breast cancer survivorship and adverse mental health outcomes: A matched population-based cohort study in the United Kingdom, PLoS Med, vol. 18, p. e1003504, 2021.
M. Kerkhof, Tran, T. N., Allehebi, R., Canonica, G. W., Heaney, L. G., Hew, M., L. de Llano, P., Wechsler, M. E., Bulathsinhala, L., Carter, V. A., Chaudhry, I., Eleangovan, N., Murray, R. B., Price, C. A., and Price, D. B., Asthma phenotyping in primary care: applying the International Severe Asthma Registry eosinophil phenotype algorithm across all asthma severities, J Allergy Clin Immunol Pract, 2021.
R. J. Silverwood, Mansfield, K. E., Mulick, A., Wong, A. Y. S., Schmidt, S. A. J., Roberts, A., Smeeth, L., Abuabara, K., and Langan, S. M., Atopic eczema in adulthood and mortality: UK population-based cohort study, 1998-2016, J Allergy Clin Immunol, 2021.
S. C. Chung, Sofat, R., Acosta-Mena, D., Taylor, J. A., Lambiase, P. D., Casas, J. P., and Providencia, R., Atrial fibrillation epidemiology, disparity and healthcare contacts: a population-wide study of 5.6 million individuals, Lancet Reg Health Eur, vol. 7, p. 100157, 2021.
E. Ford, Sheppard, J., Oliver, S., Rooney, P., Banerjee, S., and Cassell, J. A., Automated detection of patients with dementia whose symptoms have been identified in primary care but have no formal diagnosis: a retrospective case-control study using electronic primary care records, BMJ Open, vol. 11, p. e039248, 2021.
D. E. Robinson, Douglas, I., Tan, G. D., Delmestri, A., Judge, A., Cooper, C., Javaid, M. K., Strauss, V. Y., and Prieto-Alhambra, D., Bariatric surgery increases the rate of major fracture: self controlled case series study in UK Clinical Practice Research Datalink, J Bone Miner Res, 2021.
V. R. Varma, Wang, Y., An, Y., Varma, S., Bilgel, M., Doshi, J., Legido-Quigley, C., Delgado, J. C., Oommen, A. M., Roberts, J. A., Wong, D. F., Davatzikos, C., Resnick, S. M., Troncoso, J. C., Pletnikova, O., O'Brien, R., Hak, E., Baak, B. N., Pfeiffer, R., Baloni, P., Mohmoudiandehkordi, S., Nho, K., Kaddurah-Daouk, R., Bennett, D. A., Gadalla, S. M., and Thambisetty, M., Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study, PLoS Med, vol. 18, p. e1003615, 2021.
D. E. Robinson, Ali, M. S., Strauss, V. Y., Elhussein, L., Abrahamsen, B., Arden, N. K., Ben-Shlomo, Y., Caskey, F., Cooper, C., Dedman, D., Delmestri, A., Judge, A., Javaid, M. K., and Prieto-Alhambra, D., Bisphosphonates to reduce bone fractures in stage 3B+ chronic kidney disease: a propensity score-matched cohort study, Health Technol Assess, vol. 25, pp. 1-106, 2021.
M. Iwagami, Qizilbash, N., Gregson, J., Douglas, I., Johnson, M., Pearce, N., Evans, S., and Pocock, S., Blood cholesterol and risk of dementia in more than 1.8 million people over two decades: a retrospective cohort study, Lancet Healthy Longev, vol. 2, no. 8, pp. e498-e506, 2021.
C. L. Haase, Eriksen, K. T., Lopes, S., Satylganova, A., Schnecke, V., and McEwan, P., Body mass index and risk of obesity-related conditions in a cohort of 2.9 million people: Evidence from a UK primary care database, Obes Sci Pract, vol. 7, pp. 137-147, 2021.
E. Aris, Harrington, L., Bhavsar, A., Simeone, J. C., Ramond, A., Papi, A., Vogelmeier, C. F., Meszaros, K., Lambrelli, D., and Mukherjee, P., Burden of Pertussis in COPD: A Retrospective Database Study in England, Copd, pp. 1-21, 2021.
G. Funston, Mounce, L. T., Price, S., Rous, B., Crosbie, E. J., Hamilton, W., and Walter, F. M., CA125 test result, test-to-diagnosis interval, and stage in ovarian cancer at diagnosis: a retrospective cohort study using electronic health records, Br J Gen Pract, 2021.
K. Ngaosuwan, Johnston, D. G., Godsland, I. F., Cox, J., Majeed, A., Quint, J. K., Oliver, N., and Robinson, S., Cardiovascular disease in patients with primary and secondary adrenal insufficiency and the role of comorbidities, J Clin Endocrinol Metab, 2021.
B. Coles, Zaccardi, F., Hvid, C., Davies, M. J., and Khunti, K., Cardiovascular events and mortality in people with type 2 diabetes and multimorbidity: A real-world study of patients followed for up to 19 years, Diabetes Obes Metab, vol. 23, pp. 218-227, 2021.
V. Hoffman, Hallas, J., Linder, M., Margulis, A. V., Suehs, B. T., Arana, A., Phiri, K., Enger, C., Horter, L., Odsbu, I., Olesen, M., Perez-Gutthann, S., Xu, Y., Kristiansen, N. S., Appenteng, K., de Vogel, S., and Seeger, J. D., Cardiovascular Risk in Users of Mirabegron Compared with Users of Antimuscarinic Treatments for Overactive Bladder: Findings from a Non-Interventional, Multinational, Cohort Study, Drug Saf, vol. 44, pp. 899-915, 2021.
B. L. Neuen, Weldegiorgis, M., Herrington, W. G., Ohkuma, T., Smith, M., and Woodward, M., Changes in GFR and Albuminuria in Routine Clinical Practice and the Risk of Kidney Disease Progression, Am J Kidney Dis, 2021.
S. S. R. Crossfield, Buch, M. H., Baxter, P., Kingsbury, S. R., Pujades-Rodriguez, M., and Conaghan, P. G., Changes in the pharmacological management of rheumatoid arthritis over two decades, Rheumatology (Oxford), 2021.
X. Li, Ostropolets, A., Makadia, R., Shoaibi, A., Rao, A., Sena, A. G., Martinez-Hernandez, E., Verhamme, K., Rijnbeek, P., Ryan, P. B., and Prieto-Alhambra, D., Characterising the background incidence rates of adverse events of special interest for covid-19 vaccines in eight countries: multinational network cohort study, BMJ, 2021.
C. L. Morgan, Jenkins-Jones, S., Knaggs, R., Currie, C., Conway, P., Poole, C. D., and Berni, E., Characterization and Associated Costs of Constipation Relating to Exposure to Strong Opioids in England: An Observational Study, Clin Ther, 2021.
C. Koshiaris, Van den Bruel, A., Nicholson, B. D., Lay-Flurrie, S., Hobbs, F. R., and Oke, J. L., Clinical prediction tools to identify patients at highest risk of myeloma in primary care: a retrospective open cohort study, Br J Gen Pract, vol. 71, pp. e347-e355, 2021.
C. Rebordosa, Plana, E., Rubino, A., Aguado, J., Lei, A., Daoud, S., Saigi-Morgui, N., Perez-Gutthann, S., and Rivero-Ferrer, E., A Cohort Study to Evaluate the Risk of Hospitalisation for Congestive Heart Failure Associated with the Use of Aclidinium and Other Chronic Obstructive Pulmonary Disease Medications in the UK Clinical Practice Research Datalink, Int J Chron Obstruct Pulmon Dis, vol. 16, pp. 1461-1475, 2021.
L. Bullock, Bedson, J., Chen, Y., Chew-Graham, C. A., and Campbell, P., Comparative differences in musculoskeletal pain consultation and analgesic prescription for people with dementia: a UK-wide matched cohort study, Pain, 2021.
S. Suissa, Dell'Aniello, S., and Ernst, P., Comparative Effectiveness of Initial LAMA versus LABA in COPD: Real-World Cohort Study, Copd, vol. 18, pp. 1-8, 2021.
C. R. Dormuth, Winquist, B., Fisher, A., Wu, F., Reynier, P., Suissa, S., Dahl, M., Ma, Z., Lu, X., Zhang, J., Raymond, C. B., Filion, K. B., Platt, R. W., Moriello, C., and Paterson, J. M., Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort, JAMA Netw Open, vol. 4, p. e215329, 2021.
C. S. Arhi, Dudley, R., Moussa, O., Ardissino, M., Scholtz, S., and Purkayastha, S., The Complex Association Between Bariatric Surgery and Depression: a National Nested-Control Study, Obes Surg, 2021.
A. M. Trafford, Parisi, R., Rutter, M. K., Kontopantelis, E., Griffiths, C. E. M., and Ashcroft, D. M., Concordance and timing in recording cancer events in primary care, hospital and mortality records for patients with and without psoriasis: A population-based cohort study, PLoS One, vol. 16, p. e0254661, 2021.
Y. Li, Sperrin, M., Ashcroft, D. M., and van Staa, T. P., Consistency of ranking was evaluated as new measure for prediction model stability: longitudinal cohort study, J Clin Epidemiol, vol. 138, pp. 168-177, 2021.
T. Denee, Kerr, C., Ming, T., Wood, R., Tritton, T., Middleton-Dalby, C., Massey, O., and Desai, M., Current treatments used in clinical practice for major depressive disorder and treatment resistant depression in England: A retrospective database study, J Psychiatr Res, vol. 139, pp. 172-178, 2021.
V. Kuan, Fraser, H. C., Hingorani, M., Denaxas, S., Gonzalez-Izquierdo, A., Direk, K., Nitsch, D., Mathur, R., Parisinos, C. A., Lumbers, R. T., Sofat, R., Wong, I. C. K., Casas, J. P., Thornton, J. M., Hemingway, H., Partridge, L., and Hingorani, A. D., Data-driven identification of ageing-related diseases from electronic health records, Sci Rep, vol. 11, p. 2938, 2021.
R. Pradhan, Abrahami, D., Yin, H., Yu, O. H. Y., Sahasrabudhe, V., E. Andre, B., and Azoulay, L., Defining Clinically-Relevant Target Populations Using Real-World Data to Guide the Design of Representative Antidiabetic Drug Trials, Clin Pharmacol Ther, 2021.
S. Sekelj, Sandler, B., Johnston, E., Pollock, K. G., Hill, N. R., Gordon, J., Tsang, C., Khan, S., Ng, F. S., and Farooqui, U., Detecting undiagnosed atrial fibrillation in UK primary care: Validation of a machine learning prediction algorithm in a retrospective cohort study, Eur J Prev Cardiol, vol. 28, pp. 598-605, 2021.
J. van Dalem, M. Brouwers, C., Burden, A. M., C, D. A. Stehouw, Klungel, O. H., de Vries, F., and J. Driessen, H., "Determinants of treatment modification before and after implementation of the updated 2015 NICE guideline on type 2 diabetes: a retrospective cohort study", Diabetes Res Clin Pract, p. 108828, 2021.