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UK data driving real-world evidence
Bibliography
Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,700 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 4 March 2021) and papers are listed below and in the PDF below.
If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.
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(PDF, 3MB, 220 pages)This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website.
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“Data-driven identification of ageing-related diseases from electronic health records”, Sci Rep, vol. 11, p. 2938, 2021.
, , “Data-driven discovery of changes in clinical code usage over time: a case-study on changes in cardiovascular disease recording in two English electronic health records databases (2001-2015)”, BMJ Open, vol. 10, p. e034396, 2020.
, “Deep learning for electronic health records: A comparative review of multiple deep neural architectures”, J Biomed Inform, vol. 101, p. 103337, 2020.
, “Delays in referral from primary care worsen survival for patients with colorectal cancer: a retrospective cohort study”, Br J Gen Pract, vol. 70, pp. e463-e471, 2020.
, , “Determinants of referral of women with urinary incontinence to specialist services: a national cohort study using primary care data from the UK”, BMC Fam Pract, vol. 21, p. 211, 2020.
, “Determination of healthcare resource and cost implications of using alternative sodium valproate formulations in the treatment of epilepsy in children in England: a retrospective database review”, Eur J Pharm Biopharm, 2020.
, “Development and Validation of a Clinical Prediction Tool for Seasonal Influenza Vaccination in England”, JAMA Netw Open, vol. 3, p. e207743, 2020.
, “Development and Validation of a Method to Estimate COPD Severity in Multiple Datasets: A Retrospective Study”, Pulm Ther, 2020.
, “Development and validation of a multivariable prediction model for infection-related complications in patients with common infections in UK primary care and the extent of risk-based prescribing of antibiotics”, BMC Med, vol. 18, p. 118, 2020.
, “Development and validation of the Cambridge Multimorbidity Score”, Cmaj, vol. 192, pp. E107-e114, 2020.
, “Development and validation of the DIabetes Severity SCOre (DISSCO) in 139 626 individuals with type 2 diabetes: a retrospective cohort study”, BMJ Open Diabetes Res Care, vol. 8, 2020.
, “Development of a structured clinical pharmacology review for specialist support for management of complex polypharmacy in primary care”, Br J Clin Pharmacol, 2020.
, “The diagnostic performance of CA125 for the detection of ovarian and non-ovarian cancer in primary care: A population-based cohort study”, PLoS Med, vol. 17, p. e1003295, 2020.
, “Disease Activity in Inflammatory Bowel Disease Is Associated With Arterial Vascular Disease”, Inflamm Bowel Dis, 2020.
, “Dose-dependent oral glucocorticoid cardiovascular risks in people with immune-mediated inflammatory diseases: A population-based cohort study”, PLoS Med, vol. 17, p. e1003432, 2020.
, “Data resource profile: Clinical Practice Research Datalink (CPRD) Aurum”, Int J Epidemiol, 2019.
, “Degree of serotonin reuptake inhibition of antidepressants and ischemic risk: A cohort study”, Neurology, vol. 93, pp. e1010-e1020, 2019.
, “Delays in referral from primary care are associated with a worse survival in patients with esophagogastric cancer”, Dis Esophagus, 2019.
, “Descriptive epidemiology of hip and knee replacement in rheumatoid arthritis: an analysis of UK electronic medical records”, Semin Arthritis Rheum, 2019.
, “Determinants of shingles vaccine acceptance in the United Kingdom”, PLoS One, vol. 14, p. e0220230, 2019.
, “Development and validation of a prediction model to estimate the risk of liver cirrhosis in primary care patients with abnormal liver blood test results: protocol for an electronic health record study in Clinical Practice Research Datalink”, Diagn Progn Res, vol. 3, p. 10, 2019.
, “Diabetes, Metformin, and Cancer Risk in Myotonic Dystrophy Type I”, Int J Cancer, 2019.
, “Diagnostic tests, drug prescriptions, and follow-up patterns after incident heart failure: A cohort study of 93,000 UK patients”, PLoS Med, vol. 16, p. e1002805, 2019.
, “Differences in COPD exacerbation risk between women and men: analysis from the UK Clinical Practice Research Datalink data”, Chest, 2019.
, “Dipeptidyl Peptidase-4 Inhibitors and the Risk of Bullous Pemphigoid Among Patients With Type 2 Diabetes”, Diabetes Care, 2019.
, “Discontinuation and primary care visits in nonvalvular atrial fibrillation patients treated with apixaban or warfarin”, J Comp Eff Res, 2019.
, “Do beta-adrenoreceptor blocking drugs associate with reduced risk of symptomatic osteoarthritis and total joint replacement in the general population? A primary care-based, prospective cohort study using the Clinical Practice Research Datalink”, BMJ Open, vol. 9, p. e032050, 2019.
, “Do population-level risk prediction models that use routinely collected health data reliably predict individual risks?”, Sci Rep, vol. 9, p. 11222, 2019.
, “Does the use of incretin-based medications increase the risk of cancer in patients with type-2 diabetes mellitus?”, Pharmacoepidemiol Drug Saf, 2019.
, “Doubly robust estimation of the weighted average treatment effect for a target population”, Stat Med, vol. 38, pp. 315-325, 2019.
, “DPP-4 Inhibitor Dose Selection According to Manufacturer Specifications: A Contemporary Experience From UK General Practice”, Clin Ther, vol. 41, pp. 1622-1630, 2019.
, “Drug utilization patterns and healthcare resource use and costs in patients with neurogenic bladder in the United Kingdom: A retrospective primary care database study”, Neurourol Urodyn, 2019.
, , , “Demographic and Clinical Characteristics of COPD Patients at Different Blood Eosinophil Levels in the UK Clinical Practice Research Datalink”, Copd, vol. 15, pp. 177-184, 2018.
, “Determinants of health care costs in the senior elderly: age, comorbidity, impairment, or proximity to death?”, Eur J Health Econ, vol. 19, pp. 831-842, 2018.
, , “The diagnosis, burden and prognosis of dementia: A record-linkage cohort study in England”, PLoS One, vol. 13, p. e0199026, 2018.
, “Dipeptidyl peptidase-4 inhibitors and incidence of inflammatory bowel disease among patients with type 2 diabetes: population based cohort study”, Bmj, vol. 360, p. k872, 2018.
, “Do care plans and annual reviews of physical health influence unplanned hospital utilisation for people with serious mental illness? Analysis of linked longitudinal primary and secondary healthcare records in England”, BMJ Open, vol. 8, p. e023135, 2018.
, “Do delays in data availability limit the implementation of near real-time vaccine safety surveillance using the Clinical Practice Research Datalink?”, Pharmacoepidemiol Drug Saf, vol. 27, pp. 25-29, 2018.
, “Do GPs accurately record date of death? A UK observational analysis”, BMJ Support Palliat Care, 2018.
, “Does bone mineral density improve the predictive accuracy of fracture risk assessment? A prospective cohort study in Northern Denmark”, BMJ Open, vol. 8, p. e018898, 2018.
, “Domperidone for insufficient lactation in England 2002-2015: A drug utilization study with interrupted time series analysis”, Pharmacoepidemiol Drug Saf, vol. 27, pp. 1316-1324, 2018.
, “Domperidone use and risk of primary liver cancer in the Clinical Practice Research Datalink”, Cancer Epidemiol, vol. 55, pp. 170-175, 2018.
, , “Dapagliflozin therapy for type 2 diabetes in primary care: Changes in HbA1c, weight and blood pressure over 2 years follow-up”, Prim Care Diabetes, vol. 11, pp. 437-444, 2017.
, “Declining blood pressure and intensification of blood pressure management among people over 80 years: cohort study using electronic health records”, J Hypertens, vol. 35, pp. 1276-1282, 2017.
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