Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 December 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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2019
G. Muduma, Aluvihare, V., Clancy, M., de Nigris, E., Whitlock, C., Landeira, M., and Nazir, J., “The Last Year Before Graft Failure Negatively Impacts Economic Outcomes and is Associated With Greater Healthcare Resource Utilization Compared With Previous Years in the United Kingdom: Results of a Retrospective Observational Study”, Transplant Direct, vol. 5, p. e443, 2019.
R. K. Akyea, Kai, J., Qureshi, N., Iyen, B., and Weng, S. F., “LDL cholesterol response to statins and future risk of cardiovascular disease”, Heart, vol. 105, pp. 1290-1291, 2019.
H. Strongman, Williams, R., Meeraus, W., Murray-Thomas, T., Campbell, J., Carty, L., Dedman, D., Gallagher, A., Oyinlola, J., Kousoulis, A., and Valentine, J., “Limitations for health research with restricted data collection from UK primary care”, Pharmacoepidemiol Drug Saf, 2019.
J. E. Kimpton, Carey, I. M., Threapleton, C. J. D., Robinson, A., Harris, T., Cook, D. G., DeWilde, S., and Baker, E. H., “Longitudinal exposure of English primary care patients to pharmacogenomic drugs: an analysis to inform design of pre-emptive pharmacogenomic testing”, Br J Clin Pharmacol, 2019.
M. Sabido, Thilo, H., and Guido, G., “Long-term effectiveness of bisoprolol in patients with angina: A real-world evidence study”, Pharmacol Res, vol. 139, pp. 106-112, 2019.
D. Sumilo, Nirantharakumar, K., Willis, B. H., Rudge, G., Martin, J., Gokhale, K., Thayakaran, R., Adderley, N. J., Chandan, J. S., Okoth, K., Hewston, R., Skrybant, M., Deeks, J. J., and Brocklehurst, P., “Long-term impact of giving antibiotics before skin incision versus after cord clamping on children born by caesarean section: protocol for a longitudinal study based on UK electronic health records”, BMJ Open, vol. 9, p. e033013, 2019.
2018
D. E. Robinson, van Staa, T. P., Dennison, E. M., Cooper, C., and Dixon, W. G., “The limitations of using simple definitions of glucocorticoid exposure to predict fracture risk: A cohort study”, Bone, vol. 117, pp. 83-90, 2018.
E. Badrick, Renehan, I., and Renehan, A. G., “Linkage of the UK Clinical Practice Research Datalink with the national cancer registry”, Eur J Epidemiol, 2018.
U. Koppe, Nitsch, D., Mansfield, K. E., Mathur, R., Bhaskaran, K., Batterham, R. L., Smeeth, L., and Douglas, I. J., “Long-term effects of bariatric surgery on acute kidney injury: a propensity-matched cohort in the UK Clinical Practice Research Datalink”, BMJ Open, vol. 8, p. e020371, 2018.
A. D. Mosholder, Lee, J. Y., Zhou, E. H., Kang, E. M., Ghosh, M., Izem, R., Major, J. M., and Graham, D. J., “Long-Term Risk of Acute Myocardial Infarction, Stroke, and Death With Outpatient Use of Clarithromycin: A Retrospective Cohort Study”, Am J Epidemiol, vol. 187, pp. 786-792, 2018.
A. Dregan, Ravindrarajah, R., Charlton, J., Ashworth, M., and Molokhia, M., “Long-term trends in antithrombotic drug prescriptions among adults aged 80 years and over from primary care: a temporal trends analysis using electronic health records”, Ann Epidemiol, vol. 28, pp. 440-446, 2018.
A. Rao, Kim, D., Darzi, A., Majeed, A., Aylin, P., and Bottle, A., “Long-term trends of use of health service among heart failure patients”, Eur Heart J Qual Care Clin Outcomes, vol. 4, pp. 220-231, 2018.
R. M. Joseph, Ray, D. W., Keevil, B., van Staa, T. P., and Dixon, W. G., “Low salivary cortisol levels in patients with rheumatoid arthritis exposed to oral glucocorticoids: a cross-sectional study set within UK electronic health records”, RMD Open, vol. 4, p. e000700, 2018.
2017
T. A. Yates, Tomlinson, L. A., Bhaskaran, K., Langan, S., Thomas, S., Smeeth, L., and Douglas, I. J., “Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research Datalink: A population based cohort”, PLoS Med, vol. 14, p. e1002457, 2017.
A. K. Wright, Kontopantelis, E., Emsley, R., Buchan, I., Sattar, N., Rutter, M. K., and Ashcroft, D. M., “Life Expectancy and Cause-Specific Mortality in Type 2 Diabetes: A Population-Based Cohort Study Quantifying Relationships in Ethnic Subgroups”, Diabetes Care, vol. 40, pp. 338-345, 2017.
G. Bouras, Burns, E. M., Howell, A. M., Bottle, A., Athanasiou, T., and Darzi, A., “Linked hospital and primary care database analysis of the impact of short-term complications on recurrence in laparoscopic inguinal hernia repair”, Hernia, vol. 21, pp. 191-198, 2017.
S. Turner, Richardson, K., Murray, C., Thomas, M., Hillyer, E. V., Burden, A., and Price, D. B., “Long-Acting beta-Agonist in Combination or Separate Inhaler as Step-Up Therapy for Children with Uncontrolled Asthma Receiving Inhaled Corticosteroids”, J Allergy Clin Immunol Pract, vol. 5, pp. 99-106.e3, 2017.
S. Suissa, Dell'Aniello, S., and Ernst, P., “Long-Acting Bronchodilator Initiation in COPD and the Risk of Adverse Cardiopulmonary Events: A Population-Based Comparative Safety Study”, Chest, vol. 151, pp. 60-67, 2017.
E. Kontopantelis, Parisi, R., Springate, D. A., and Reeves, D., “Longitudinal multiple imputation approaches for body mass index or other variables with very low individual-level variability: the mibmi command in Stata”, BMC Res Notes, vol. 10, p. 41, 2017.
J. H. Driessen, van den Bergh, J. P., van Onzenoort, H. A., Henry, R. M., Leufkens, H. G., and de Vries, F., “Long-term use of dipeptidyl peptidase-4 inhibitors and risk of fracture: A retrospective population-based cohort study”, Diabetes Obes Metab, vol. 19, pp. 421-428, 2017.
J. W. Wu, Azoulay, L., Majdan, A., Boivin, J. F., Pollak, M., and Suissa, S., “Long-Term Use of Long-Acting Insulin Analogs and Breast Cancer Incidence in Women With Type 2 Diabetes”, J Clin Oncol, vol. 35, pp. 3647-3653, 2017.
2016
R. Beau-Lejdstrom, Douglas, I., Evans, S. J., and Smeeth, L., “Latest trends in ADHD drug prescribing patterns in children in the UK: prevalence, incidence and persistence”, BMJ Open, vol. 6, p. e010508, 2016.
M. Bloechliger, Ceschi, A., Ruegg, S., Jick, S. S., Meier, C. R., and Bodmer, M., “Lifestyle factors, psychiatric and neurologic comorbidities, and drug use associated with incident seizures among adult patients with depression: a population-based nested case-control study”, Eur J Epidemiol, vol. 31, pp. 1113-1122, 2016.
E. Moore, Chatzidiakou, L., Jones, R. L., Smeeth, L., Beevers, S., Kelly, F. J., K. J, Q., and Barratt, B., “Linking e-health records, patient-reported symptoms and environmental exposure data to characterise and model COPD exacerbations: protocol for the COPE study”, BMJ Open, vol. 6, p. e011330, 2016.
2015
R. W. Atkinson, Carey, I. M., Kent, A. J., van Staa, T. P., Anderson, H. R., and Cook, D. G., “Long-term exposure to outdoor air pollution and the incidence of chronic obstructive pulmonary disease in a national English cohort”, Occup Environ Med, vol. 72, pp. 42-8, 2015.
U. C. Mc Menamin, Cardwell, C. R., Hughes, C. M., and Murray, L. M., “Low-dose aspirin and survival from lung cancer: a population-based cohort study”, BMC Cancer, vol. 15, p. 911, 2015.
2014
R. G. Duijnhoven, Straus, S. M., Souverein, P. C., de Boer, A., Bosch, J. L., Hoes, A. W., and De Bruin, M. L., “Long-term use of 5alpha-reductase inhibitors and the risk of male breast cancer”, Cancer Causes Control, vol. 25, pp. 1577-82, 2014.
C. R. Cardwell, Flahavan, E. M., Hughes, C. M., Coleman, H. G., O'Sullivan, J. M., Powe, D. G., and Murray, L. J., “Low-dose aspirin and survival in men with prostate cancer: a study using the UK Clinical Practice Research Datalink”, Cancer Causes Control, vol. 25, pp. 33-43, 2014.
C. R. Cardwell, Kunzmann, A. T., Cantwell, M. M., Hughes, C., Baron, J. A., Powe, D. G., and Murray, L. J., “Low-dose aspirin use after diagnosis of colorectal cancer does not increase survival: a case-control analysis of a population-based cohort”, Gastroenterology, vol. 146, pp. 700-708.e2, 2014.
2013
R. W. Atkinson, Carey, I. M., Kent, A. J., van Staa, T. P., Anderson, H. R., and Cook, D. G., “Long-term exposure to outdoor air pollution and incidence of cardiovascular diseases”, Epidemiology, vol. 24, pp. 44-53, 2013.
J. A. Lopez Bernal, Upton, M. N., Henderson, A. J., Dedman, D., McCarthy, A., G. Smith, D., and Ben-Shlomo, Y., “Lower respiratory tract infection in the first year of life is associated with worse lung function in adult life: prospective results from the Barry Caerphilly Growth study”, Ann Epidemiol, vol. 23, pp. 422-7, 2013.
2012
D. C. Perry, Bruce, C. E., Pope, D., Dangerfield, P., Platt, M. J., and Hall, A. J., “Legg-Calve-Perthes disease in the UK: geographic and temporal trends in incidence reflecting differences in degree of deprivation in childhood”, Arthritis Rheum, vol. 64, pp. 1673-9, 2012.
D. J. Culliford, Maskell, J., Kiran, A., Judge, A., Javaid, M. K., Cooper, C., and Arden, N. K., “The lifetime risk of total hip and knee arthroplasty: results from the UK general practice research database”, Osteoarthritis Cartilage, vol. 20, pp. 519-24, 2012.
I. Le Ray, Dell'Aniello, S., Bonnetain, F., Azoulay, L., and Suissa, S., “Local estrogen therapy and risk of breast cancer recurrence among hormone-treated patients: a nested case-control study”, Breast Cancer Res Treat, vol. 135, pp. 603-9, 2012.
L. Azoulay, Assimes, T. L., Yin, H., Bartels, D. B., Schiffrin, E. L., and Suissa, S., “Long-term use of angiotensin receptor blockers and the risk of cancer”, PLoS One, vol. 7, p. e50893, 2012.
2011
F. Kelly, Armstrong, B., Atkinson, R., Anderson, H. R., Barratt, B., Beevers, S., Cook, D., Green, D., Derwent, D., Mudway, I., and Wilkinson, P., “The London low emission zone baseline study”, Res Rep Health Eff Inst, pp. 3-79, 2011.
S. Suissa, Azoulay, L., Dell'Aniello, S., Evans, M., Vora, J., and Pollak, M., “Long-term effects of insulin glargine on the risk of breast cancer”, Diabetologia, vol. 54, pp. 2254-62, 2011.
N. F. Khan, Mant, D., Carpenter, L., Forman, D., and Rose, P. W., “Long-term health outcomes in a British cohort of breast, colorectal and prostate cancer survivors: a database study”, Br J Cancer, vol. 105 Suppl 1, pp. S29-37, 2011.
D. P. Miller, Watkins, S. E., Sampson, T., and Davis, K. J., “Long-term use of fluticasone propionate/salmeterol fixed-dose combination and incidence of cataracts and glaucoma among chronic obstructive pulmonary disease patients in the UK General Practice Research Database”, Int J Chron Obstruct Pulmon Dis, vol. 6, pp. 467-76, 2011.
A. C. Shafe, Lee, S., Dalrymple, J. S., and Whorwell, P. J., “The LUCK study: Laxative Usage in patients with GP-diagnosed Constipation in the UK, within the general population and in pregnancy. An epidemiological study using the General Practice Research Database (GPRD)”, Therap Adv Gastroenterol, vol. 4, pp. 343-63, 2011.
2010
S. E. McDowell, Coleman, J. J., Evans, S. J., Gill, P. S., and Ferner, R. E., “Laboratory monitoring and adverse patient outcomes with antihypertensive therapy in primary care”, Pharmacoepidemiol Drug Saf, vol. 19, pp. 482-9, 2010.
F. de Vries, Setakis, E., Zhang, B., and van Staa, T. P., “Long-acting {beta}2-agonists in adult asthma and the pattern of risk of death and severe asthma outcomes: a study using the GPRD”, Eur Respir J, vol. 36, pp. 494-502, 2010.
M. Bodmer, Meier, C., Krahenbuhl, S., Jick, S. S., and Meier, C. R., “Long-term metformin use is associated with decreased risk of breast cancer”, Diabetes Care, vol. 33, pp. 1304-8, 2010.
D. P. Miller, Watkins, S. E., Sampson, T., and Davis, K. J., “Long-term use of fluticasone propionate/salmeterol fixed-dose combination and incidence of nonvertebral fractures among patients with COPD in the UK General Practice Research Database”, Phys Sportsmed, vol. 38, pp. 19-27, 2010.
2009
Y. B. Brauchli, Jick, S. S., Curtin, F., and Meier, C. R., “Lithium, antipsychotics, and risk of psoriasis”, J Clin Psychopharmacol, vol. 29, pp. 134-40, 2009.
F. Andersohn, Schade, R., Suissa, S., and Garbe, E., “Long-term use of antidepressants for depressive disorders and the risk of diabetes mellitus”, Am J Psychiatry, vol. 166, pp. 591-8, 2009.
2008
H. Phatak, Wentworth, C., and Burke, T. A., “Lipid testing among patients beginning statin therapy in general practice in the United Kingdom”, Value Health, vol. 11, pp. 933-8, 2008.
S. Cheeta, Drummond, C., Oyefeso, A., Phillips, T., Deluca, P., Perryman, K., and Coulton, S., “Low identification of alcohol use disorders in general practice in England”, Addiction, vol. 103, pp. 766-73, 2008.
2007
J. A. Delaney, Daskalopoulou, S. S., Brophy, J. M., Steele, R. J., Opatrny, L., and Suissa, S., “Lifestyle variables and the risk of myocardial infarction in the general practice research database”, BMC Cardiovasc Disord, vol. 7, p. 38, 2007.
I. Wilting, de Vries, F., Thio, B. M., Cooper, C., Heerdink, E. R., Leufkens, H. G., Nolen, W. A., Egberts, A. C., and van Staa, T. P., “Lithium use and the risk of fractures”, Bone, vol. 40, pp. 1252-8, 2007.
[Page last reviewed 6 December 2019]