Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 November 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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2019
F. Zaccardi, Husemoen, L. L. Nystrup, Thorsted, B. L., Webb, D. R., Paul, S. K., Davies, M. J., and Khunti, K., “Selectivity of beta-blockers, cardiovascular and all-cause mortality in people with hypoglycaemia: An observational study”, Nutr Metab Cardiovasc Dis, vol. 29, pp. 481-488, 2019.
C. Linde, Qin, L., Bakhai, A., Furuland, H., Evans, M., Ayoubkhani, D., Palaka, E., Bennett, H., and McEwan, P., “Serum potassium and clinical outcomes in heart failure patients: results of risk calculations in 21 334 patients in the UK”, ESC Heart Fail, 2019.
M. Rafiq, Hayward, A., Warren-Gash, C., Denaxas, S., Gonzalez-Izquierdo, A., Lyratzopoulos, G., and Thomas, S., “Socioeconomic deprivation and regional variation in Hodgkin's lymphoma incidence in the UK: a population-based cohort study of 10 million individuals”, BMJ Open, vol. 9, p. e029228, 2019.
M. Weldegiorgis, Smith, M., Herrington, W. G., Bankhead, C., and Woodward, M., “Socioeconomic disadvantage and the risk of advanced chronic kidney disease: results from a cohort study with 1.4 million participants”, Nephrology Dialysis Transplantation, 2019.
M. S. Chan, van den Hout, A., Pujades-Rodriguez, M., Jones, M. M., Matthews, F. E., Jagger, C., Raine, R., and Bajekal, M., “Socio-economic inequalities in life expectancy of older adults with and without multimorbidity: a record linkage study of 1.1 million people in England”, Int J Epidemiol, 2019.
G. J. Lefeber, Koek, H. L., Souverein, P. C., Bouvy, M. L., de Boer, A., and Knol, W., “Statins After Myocardial Infarction in the Oldest: A Cohort Study in the Clinical Practice Research Datalink Database”, J Am Geriatr Soc, 2019.
J. Fortuny, Gilsenan, A., Cainzos-Achirica, M., Cantero, O. F., Flynn, R. W. V., Garcia-Rodriguez, L., Kollhorst, B., Karlsson, P., Linner, L., MacDonald, T. M., Plana, E., Ruigomez, A., Schink, T., Ziemiecki, R., and Andrews, E. B., “Study Design and Cohort Comparability in a Study of Major Cardiovascular Events in New Users of Prucalopride Versus Polyethylene Glycol 3350”, Drug Saf, 2019.
N. A. Stohler, Reinau, D., Jick, S. S., Bodmer, D., and Meier, C. R., “A study on the epidemiology of tinnitus in the United Kingdom”, Clin Epidemiol, vol. 11, pp. 855-871, 2019.
R. K. Akyea, Kai, J., Qureshi, N., Iyen, B., and Weng, S. F., “Sub-optimal cholesterol response to initiation of statins and future risk of cardiovascular disease”, Heart, 2019.
A. Banerjee, Allan, V., Denaxas, S., Shah, A., Kotecha, D., Lambiase, P. D., Jacob, J., Lund, L. H., and Hemingway, H., “Subtypes of atrial fibrillation with concomitant valvular heart disease derived from electronic health records: phenotypes, population prevalence, trends and prognosis”, Europace, 2019.
K. B. Filion, Douros, A., Azoulay, L., Yin, H., Yu, O. H., and Suissa, S., “Sulfonylureas as initial treatment for type 2 diabetes and the risk of adverse cardiovascular events: A population-based cohort study”, Br J Clin Pharmacol, 2019.
2018
P. Bryan, Seabroke, S., Wong, J., Donegan, K., Webb, E., Goldsmith, C., Vipond, C., and Feavers, I., “Safety of multicomponent meningococcal group B vaccine (4CMenB) in routine infant immunisation in the UK: a prospective surveillance study”, Lancet Child Adolesc Health, vol. 2, pp. 395-403, 2018.
S. Muller, Hider, S., Machin, A., Stack, R., Hayward, R. A., Raza, K., and Mallen, C., “Searching for a prodrome for rheumatoid arthritis in the primary care record: A case-control study in the clinical practice research datalink”, Semin Arthritis Rheum, 2018.
E. A. Shephard and Hamilton, W. T., “Selection of men for investigation of possible testicular cancer in primary care: a large case-control study using electronic patient records”, Br J Gen Pract, vol. 68, pp. e559-e565, 2018.
J. Busby, Mills, K., Zhang, S. D., Liberante, F. G., and Cardwell, C. R., “Selective serotonin reuptake inhibitor use and breast cancer survival: a population-based cohort study”, Breast Cancer Res, vol. 20, p. 4, 2018.
C. Morgan, Webb, R. T., Carr, M. J., Kontopantelis, E., Chew-Graham, C. A., Kapur, N., and Ashcroft, D. M., “Self-harm in a primary care cohort of older people: incidence, clinical management, and risk of suicide and other causes of death”, Lancet Psychiatry, vol. 5, pp. 905-912, 2018.
H. Furuland, McEwan, P., Evans, M., Linde, C., Ayoubkhani, D., Bakhai, A., Palaka, E., Bennett, H., and Qin, L., “Serum potassium as a predictor of adverse clinical outcomes in patients with chronic kidney disease: new risk equations using the UK clinical practice research datalink”, BMC Nephrol, vol. 19, p. 211, 2018.
R. J. Silverwood, Forbes, H. J., Abuabara, K., Ascott, A., Schmidt, M., Schmidt, S. A. J., Smeeth, L., and Langan, S. M., “Severe and predominantly active atopic eczema in adulthood and long term risk of cardiovascular disease: population based cohort study”, Bmj, vol. 361, p. k1786, 2018.
M. Iwagami, Mansfield, K. E., Hayes, J. F., Walters, K., Osborn, D. P., Smeeth, L., Nitsch, D., and Tomlinson, L. A., “Severe mental illness and chronic kidney disease: a cross-sectional study in the United Kingdom”, Clin Epidemiol, vol. 10, pp. 421-429, 2018.
J. M. Dennis, Henley, W. E., Weedon, M. N., Lonergan, M., Rodgers, L. R., Jones, A. G., Hamilton, W. T., Sattar, N., Janmohamed, S., Holman, R. R., Pearson, E. R., Shields, B. M., and Hattersley, A. T., “Sex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes: A Framework for Evaluating Stratification Using Routine Clinical and Individual Trial Data”, Diabetes Care, vol. 41, pp. 1844-1853, 2018.
S. Weir, Samnaliev, M., Kuo, T. C., Tierney, T. S., S. Autiero, W., Taylor, R. S., and Schrag, A., “Short- and long-term cost and utilization of health care resources in Parkinson's disease in the UK”, Mov Disord, vol. 33, pp. 974-981, 2018.
E. Kontopantelis, Stevens, R. J., Helms, P. J., Edwards, D., Doran, T., and Ashcroft, D. M., “Spatial distribution of clinical computer systems in primary care in England in 2016 and implications for primary care electronic medical record databases: a cross-sectional population study”, BMJ Open, vol. 8, p. e020738, 2018.
Z. Liu, Alsaggaf, R., McGlynn, K. A., Anderson, L. A., Tsai, H. T., Zhu, B., Zhu, Y., Mbulaiteye, S. M., Gadalla, S. M., and Koshiol, J., “Statin use and reduced risk of biliary tract cancers in the UK Clinical Practice Research Datalink”, Gut, 2018.
A. D. Spence, Busby, J., Hughes, C. M., Johnston, B. T., Coleman, H. G., and Cardwell, C. R., “Statin use and survival in patients with gastric cancer in two independent population-based cohorts”, Pharmacoepidemiol Drug Saf, 2018.
K. Chidwick, Strongman, H., Matthews, A., Stanway, S., Lyon, A. R., Smeeth, L., and Bhaskaran, K., “Statin use in cancer survivors versus the general population: cohort study using primary care data from the UK clinical practice research datalink”, BMC Cancer, vol. 18, p. 1018, 2018.
A. Pate, Barrowman, M., Webb, D., Pimenta, J. M., Davis, K. J., Williams, R., Van Staa, T., and Sperrin, M., “Study investigating the generalisability of a COPD trial based in primary care (Salford Lung Study) and the presence of a Hawthorne effect”, BMJ Open Respir Res, vol. 5, p. e000339, 2018.
O. Yu, Azoulay, L., Yin, H., Filion, K. B., and Suissa, S., “Sulfonylureas as Initial Treatment for Type 2 Diabetes and the Risk of Severe Hypoglycemia”, Am J Med, vol. 131, pp. 317.e11-317.e22, 2018.
A. Douros, Dell'Aniello, S., Yu, O. H. Y., Filion, K. B., Azoulay, L., and Suissa, S., “Sulfonylureas as second line drugs in type 2 diabetes and the risk of cardiovascular and hypoglycaemic events: population based cohort study”, Bmj, vol. 362, p. k2693, 2018.
R. M. Joseph, Soames, J., Wright, M., Sultana, K., van Staa, T. P., and Dixon, W. G., “Supplementing electronic health records through sample collection and patient diaries: A study set within a primary care research database”, Pharmacoepidemiol Drug Saf, vol. 27, pp. 239-242, 2018.
2017
A. Ble, Hughes, P. M., Delgado, J., Masoli, J. A., Bowman, K., Zirk-Sadowski, J., Mota, R. E. Mujica, Henley, W. E., and Melzer, D., “Safety and Effectiveness of Statins for Prevention of Recurrent Myocardial Infarction in 12 156 Typical Older Patients: A Quasi-Experimental Study”, J Gerontol A Biol Sci Med Sci, vol. 72, pp. 243-250, 2017.
C. Becker, Jick, S. S., and Meier, C. R., “Selective Serotonin Reuptake Inhibitors and Cataract Risk: A Case-Control Analysis”, Ophthalmology, vol. 124, pp. 1635-1639, 2017.
R. A. Charlton, McGrogan, A., Snowball, J., Yates, L. M., Wood, A., Clayton-Smith, J., Smithson, W. H., Richardson, J. L., McHugh, N., Thomas, S. H., Baker, G. A., and Bromley, R., “Sensitivity of the UK Clinical Practice Research Datalink to Detect Neurodevelopmental Effects of Medicine Exposure in Utero: Comparative Analysis of an Antiepileptic Drug-Exposed Cohort”, Drug Saf, vol. 40, pp. 387-397, 2017.
J. C. Wilson, Sarsour, K., Collinson, N., Tuckwell, K., Musselman, D., Klearman, M., Napalkov, P., Jick, S. S., Stone, J. H., and Meier, C. R., “Serious adverse effects associated with glucocorticoid therapy in patients with giant cell arteritis (GCA): A nested case-control analysis”, Semin Arthritis Rheum, vol. 46, pp. 819-827, 2017.
M. Schmidt, Mansfield, K. E., Bhaskaran, K., Nitsch, D., Sorensen, H. T., Smeeth, L., and Tomlinson, L. A., “Serum creatinine elevation after renin-angiotensin system blockade and long term cardiorenal risks: cohort study”, Bmj, vol. 356, p. j791, 2017.
K. T. Palmer, D'Angelo, S., Harris, E. C., Linaker, C., Sayer, A. A., Gale, C. R., Evandrou, M., Van Staa, T., Cooper, C., and Coggon, D., “Sleep disturbance and the older worker: findings from the Health and Employment after Fifty study”, Scand J Work Environ Health, vol. 43, pp. 136-145, 2017.
X. Xiao, Fischbach, S., Zhang, T., Chen, C., Sheng, Q., Zimmerman, R., Patnaik, S., Fusco, J., Ming, Y., Guo, P., Shiota, C., Prasadan, K., Gangopadhyay, N., Husain, S. Z., Dong, H., and Gittes, G. K., “SMAD3/Stat3 Signaling Mediates beta-Cell Epithelial-Mesenchymal Transition in Chronic Pancreatitis-Related Diabetes”, Diabetes, vol. 66, pp. 2646-2658, 2017.
I. S. Mackenzie, Morant, S. V., Wei, L., Thompson, A. M., and MacDonald, T. M., “Spironolactone use and risk of incident cancers: a retrospective, matched cohort study”, Br J Clin Pharmacol, vol. 83, pp. 653-663, 2017.
S. H. Landis, Suruki, R., Hilton, E., Compton, C., and Galwey, N. W., “Stability of Blood Eosinophil Count in Patients with COPD in the UK Clinical Practice Research Datalink”, Copd, vol. 14, pp. 382-388, 2017.
O. A. Oshagbemi, Burden, A. M., Braeken, D. C. W., Henskens, Y., Wouters, E. F. M., Driessen, J. H. M., van der Zee, A. H. Maitlan, de Vries, F., and Franssen, F. M. E., “Stability of Blood Eosinophils in Patients with Chronic Obstructive Pulmonary Disease and in Control Subjects, and the Impact of Sex, Age, Smoking, and Baseline Counts”, Am J Respir Crit Care Med, vol. 195, pp. 1402-1404, 2017.
J. Y. Shin, Eberg, M., Ernst, P., and Filion, K. B., “Statin potency and the risk of hospitalization for community-acquired pneumonia”, Br J Clin Pharmacol, vol. 83, pp. 1319-1327, 2017.
A. McGrogan, Snowball, J., and Charlton, R. A., “Statins during pregnancy: a cohort study using the General Practice Research Database to investigate pregnancy loss”, Pharmacoepidemiol Drug Saf, vol. 26, pp. 843-852, 2017.
R. Ravindrarajah, Hazra, N. C., Hamada, S., Charlton, J., Jackson, S. H. D., Dregan, A., and Gulliford, M. C., “Systolic Blood Pressure Trajectory, Frailty, and All-Cause Mortality >80 Years of Age: Cohort Study Using Electronic Health Records”, Circulation, vol. 135, pp. 2357-2368, 2017.
2016
J. T. Nielen, Dagnelie, P. C., Emans, P. J., Veldhorst-Janssen, N., Lalmohamed, A., van Staa, T. P., Boonen, A. E., van den Bemt, B. J., and de Vries, F., “Safety and efficacy of new oral anticoagulants and low-molecular-weight heparins compared with aspirin in patients undergoing total knee and hip replacements”, Pharmacoepidemiol Drug Saf, vol. 25, pp. 1245-1252, 2016.
M. C. Gulliford, Moore, M. V., Little, P., Hay, A. D., Fox, R., Prevost, A. T., Juszczyk, D., Charlton, J., and Ashworth, M., “Safety of reduced antibiotic prescribing for self limiting respiratory tract infections in primary care: cohort study using electronic health records”, Bmj, vol. 354, p. i3410, 2016.
R. Y. van der Velde, Wyers, C. E., Curtis, E. M., Geusens, P., van den Bergh, J. P. W., de Vries, F., Cooper, C., van Staa, T. P., and Harvey, N. C., “Secular trends in fracture incidence in the UK between 1990 and 2012”, Osteoporos Int, vol. 27, pp. 3197-3206, 2016.
J. T. Nielen, Emans, P. J., Dagnelie, P. C., Boonen, A., Lalmohamed, A., de Boer, A., van den Bemt, B. J., and de Vries, F., “Severity of Diabetes Mellitus and Total Hip or Knee Replacement: A Population-Based Case-Control Study”, Medicine (Baltimore), vol. 95, p. e3739, 2016.
H. P. Booth, Prevost, A. T., and Gulliford, M. C., “Severity of obesity and management of hypertension, hypercholesterolaemia and smoking in primary care: population-based cohort study”, J Hum Hypertens, vol. 30, pp. 40-5, 2016.
R. M. Joseph, Movahedi, M., Dixon, W. G., and Symmons, D. P., “Smoking-Related Mortality in Patients With Early Rheumatoid Arthritis: A Retrospective Cohort Study Using the Clinical Practice Research Datalink”, Arthritis Care Res (Hoboken), vol. 68, pp. 1598-1606, 2016.
C. Fairhurst, Martin, F., Watt, I., Doran, T., Bland, M., and Brackenbury, W. J., “Sodium channel-inhibiting drugs and cancer survival: protocol for a cohort study using the CPRD primary care database”, BMJ Open, vol. 6, p. e011661, 2016.
K. Tascilar, Dell'Aniello, S., Hudson, M., and Suissa, S., “Statins and Risk of Rheumatoid Arthritis: A Nested Case-Control Study”, Arthritis Rheumatol, vol. 68, pp. 2603-2611, 2016.
[Page last reviewed 4 November 2019]