Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,500 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 5 May 2020) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 3MB, 203 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 2509 results:
[ Author(Desc)] Title Type Year
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R. Alsaggaf, St George, D. M. M., Zhan, M., Pfeiffer, R. M., Wang, Y., Anderson, L. A., Liu, Z., Koshiol, J., Bauer, A. J., Wagner, K. R., Greene, M. H., Amr, S., and Gadalla, S. M., Benign tumors in myotonic dystrophy type I target disease-related cancer sites, Ann Clin Transl Neurol, vol. 6, pp. 1510-1518, 2019.
R. Alsaggaf, Pfeiffer, R. M., Wang, Y., St George, D. M. M., Zhan, M., Wagner, K. R., Amr, S., Greene, M. H., and Gadalla, S. M., Diabetes, Metformin, and Cancer Risk in Myotonic Dystrophy Type I, Int J Cancer, 2019.
R. K. Amar, Jick, S. S., Rosenberg, D., Maher, T. M., and Meier, C. R., Drug-/radiation-induced interstitial lung disease in the United Kingdom general population: incidence, all-cause mortality and characteristics at diagnosis, Respirology, vol. 17, pp. 861-8, 2012.
R. K. Amar, Jick, S. S., Rosenberg, D., Maher, T. M., and Meier, C. R., Incidence of the pneumoconioses in the United Kingdom general population between 1997 and 2008, Respiration, vol. 84, pp. 200-6, 2012.
J. E. Amegadzie, Badejo, O., Gamble, J. M., Wright, M., Farrell, J., Jackson, B., Sultana, K., Hashmi, M., and Gao, Z., Validated methods to identify patients with asthma-COPD overlap in healthcare databases: a systematic review protocol, BMJ Open, vol. 9, p. e024306, 2019.
G. Amirthalingam, Andrews, N., Campbell, H., Ribeiro, S., Kara, E., Donegan, K., Fry, N. K., Miller, E., and Ramsay, M., Effectiveness of maternal pertussis vaccination in England: an observational study, Lancet, vol. 384, pp. 1521-8, 2014.
G. Amirthalingam, Campbell, H., Ribeiro, S., Fry, N. K., Ramsay, M., Miller, E., and Andrews, N., Sustained Effectiveness of the Maternal Pertussis Immunization Program in England 3 Years Following Introduction, Clin Infect Dis, vol. 63, pp. S236-s243, 2016.
Y. M. F. Andersen, Egeberg, A., Ban, L., Gran, S., Williams, H. C., Francis, N. A., Knop, F. K., Gislason, G. H., Skov, L., and Thyssen, J. P., Association Between Topical Corticosteroid Use and Type 2 Diabetes in Two European Population-Based Adult Cohorts, Diabetes Care, vol. 42, pp. 1095-1103, 2019.
F. Andersohn, Schade, R., Suissa, S., and Garbe, E., Cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs and the risk of ischemic stroke: a nested case-control study, Stroke, vol. 37, pp. 1725-30, 2006.
F. Andersohn, Suissa, S., and Garbe, E., Use of first- and second-generation cyclooxygenase-2-selective nonsteroidal antiinflammatory drugs and risk of acute myocardial infarction, Circulation, vol. 113, pp. 1950-7, 2006.
F. Andersohn, Schade, R., Suissa, S., and Garbe, E., Long-term use of antidepressants for depressive disorders and the risk of diabetes mellitus, Am J Psychiatry, vol. 166, pp. 591-8, 2009.
F. Andersohn, Schade, R., Willich, S. N., and Garbe, E., Use of antiepileptic drugs in epilepsy and the risk of self-harm or suicidal behavior, Neurology, vol. 75, pp. 335-40, 2010.
F. Andersohn, Waring, M., and Garbe, E., Risk of ischemic stroke in patients with Crohn's disease: a population-based nested case-control study, Inflamm Bowel Dis, vol. 16, pp. 1387-92, 2010.
N. Andrews, Miller, E., Waight, P., Farrington, P., Crowcroft, N., Stowe, J., and Taylor, B., Does oral polio vaccine cause intussusception in infants? Evidence from a sequence of three self-controlled cases series studies in the United Kingdom, Eur J Epidemiol, vol. 17, pp. 701-6, 2001.
N. Andrews, Miller, E., Grant, A., Stowe, J., Osborne, V., and Taylor, B., Thimerosal exposure in infants and developmental disorders: a retrospective cohort study in the United kingdom does not support a causal association, Pediatrics, vol. 114, pp. 584-91, 2004.
C. Ang, Doyle, E., and Branch, A., Bisphosphonates as potential adjuvants for patients with cancers of the digestive system, World J Gastroenterol, vol. 22, pp. 906-16, 2016.
M. Z. Ankarfeldt, Thorsted, B. L., Groenwold, R. H., Adalsteinsson, E., Ali, M. S., and Klungel, O. H., Assessment of channeling bias among initiators of glucose-lowering drugs: A UK cohort study, Clin Epidemiol, vol. 9, pp. 19-30, 2017.
E. Ankus, Price, S. J., Ukoumunne, O. C., Hamilton, W., and Bailey, S. E. R., Cancer incidence in patients with a high normal platelet count: a cohort study using primary care data, Fam Pract, vol. 35, pp. 671-675, 2018.
T. M. Anssar, Leitzmann, M. F., Linker, R. A., Meier, C., Becker, C., Jick, S., Sahm, K., Platten, M., Hau, P., and Seliger, C., Autoimmune diseases and immunosuppressive therapy in relation to the risk of glioma, Cancer Med, 2019.
T. Appleyard, Ashworth, J., Bedson, J., Yu, D., and Peat, G., Trends in gabapentinoid prescribing in patients with osteoarthritis: a United Kingdom national cohort study in primary care, Osteoarthritis Cartilage, 2019.
A. J. Apter, Kinman, J. L., Bilker, W. B., Herlim, M., Margolis, D. J., Lautenbach, E., Hennessy, S., and Strom, B. L., Represcription of penicillin after allergic-like events, J Allergy Clin Immunol, vol. 113, pp. 764-70, 2004.
A. J. Apter, Kinman, J. L., Bilker, W. B., Herlim, M., Margolis, D. J., Lautenbach, E., Hennessy, S., and Strom, B. L., Is there cross-reactivity between penicillins and cephalosporins?, Am J Med, vol. 119, pp. 354.e11-9, 2006.
A. Arana, Margulis, A. V., McQuay, L. J., Ziemiecki, R., Bartsch, J. L., Rothman, K. J., Franks, B., D'Silva, M., Appenteng, K., Varas-Lorenzo, C., and Perez-Gutthann, S., Variation in Cardiovascular Risk Related to Individual Antimuscarinic Drugs Used to Treat Overactive Bladder: A UK Cohort Study, Pharmacotherapy, vol. 38, pp. 628-637, 2018.
A. Arana, Johannes, C. B., McQuay, L. J., Varas-Lorenzo, C., Fife, D., and Rothman, K. J., Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Proton Pump Inhibitors, or Metoclopramide: A Population-Based Nested Case-Control Study, Drug Saf, vol. 38, pp. 1187-99, 2015.
A. Arana, Varas, C., Gonzalez-Perez, A., Gutierrez, L., Bjerrum, L., and Rodriguez, L. A. Garcia, Hormone therapy and cerebrovascular events: a population-based nested case-control study, Menopause, vol. 13, pp. 730-6, 2006.
O. Archangelidi, Pujades-Rodriguez, M., Timmis, A., Jouven, X., Denaxas, S., and Hemingway, H., Clinically recorded heart rate and incidence of 12 coronary, cardiac, cerebrovascular and peripheral arterial diseases in 233,970 men and women: A linked electronic health record study, Eur J Prev Cardiol, vol. 25, pp. 1485-1495, 2018.
N. Arden, Altman, D., Beard, D., Carr, A., Clarke, N., Collins, G., Cooper, C., Culliford, D., Delmestri, A., Garden, S., Griffin, T., Javaid, K., Judge, A., Latham, J., Mullee, M., Murray, D., Ogundimu, E., Pinedo-Villanueva, R., Price, A., Prieto-Alhambra, D., and Raftery, J., Programme Grants for Applied Research, in Lower limb arthroplasty: can we produce a tool to predict outcome and failure, and is it cost-effective? An epidemiological study, Southampton (UK): NIHR Journals Library Copyright (c) Queen's Printer and Controller of HMSO 2017. This work was produced by Arden et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the pu, 2017.
M. Ardissino, Moussa, O., Tang, A., Muttoni, E., Ziprin, P., and Purkayastha, S., Idiopathic intracranial hypertension in the British population with obesity, Acta Neurochir (Wien), 2018.
C. S. Arhi, Bottle, A., Burns, E. M., Clarke, J. M., Aylin, P., Ziprin, P., and Darzi, A., Comparison of cancer diagnosis recording between the Clinical Practice Research Datalink, Cancer Registry and Hospital Episodes Statistics, Cancer Epidemiol, vol. 57, pp. 148-157, 2018.
C. S. Arhi, Burns, E. M., Bouras, G., Aylin, P., Ziprin, P., and Darzi, A., Complications after discharge and delays in adjuvant chemotherapy following colonic resection: a cohort study of linked primary and secondary care data, Colorectal Dis, 2018.
C. S. Arhi, Markar, S., Burns, E. M., Bouras, G., Bottle, A., Hanna, G., Aylin, P., Ziprin, P., and Darzi, A., Delays in referral from primary care are associated with a worse survival in patients with esophagogastric cancer, Dis Esophagus, 2019.
R. G. Armstrong, West, J., and Card, T. R., Risk of cancer in inflammatory bowel disease treated with azathioprine: a UK population-based case-control study, Am J Gastroenterol, vol. 105, pp. 1604-9, 2010.
D. Armstrong, Ashworth, M., Dregan, A., and White, P., The relationship between prior antimicrobial prescription and meningitis: a case-control study, Br J Gen Pract, vol. 66, pp. e228-33, 2016.
M. Asaria, Walker, S., Palmer, S., Gale, C. P., Shah, A. D., Abrams, K. R., Crowther, M., Manca, A., Timmis, A., Hemingway, H., and Sculpher, M., Using electronic health records to predict costs and outcomes in stable coronary artery disease, Heart, vol. 102, pp. 755-62, 2016.
Z. Asghar, Coupland, C., and Siriwardena, N., Influenza vaccination and risk of stroke: Self-controlled case-series study, Vaccine, vol. 33, pp. 5458-5463, 2015.
M. Ashworth, Latinovic, R., Charlton, J., Cox, K., Rowlands, G., and Gulliford, M., Why has antibiotic prescribing for respiratory illness declined in primary care? A longitudinal study using the General Practice Research Database, J Public Health (Oxf), vol. 26, pp. 268-74, 2004.
M. Ashworth, Charlton, J., Ballard, K., Latinovic, R., and Gulliford, M., Variations in antibiotic prescribing and consultation rates for acute respiratory infection in UK general practices 1995-2000, Br J Gen Pract, vol. 55, pp. 603-8, 2005.
M. Ashworth, Charlton, J., Latinovic, R., and Gulliford, M., Age-related changes in consultations and antibiotic prescribing for acute respiratory infections, 1995-2000. Data from the UK General Practice Research Database, J Clin Pharm Ther, vol. 31, pp. 461-7, 2006.
J. Assayag, Pollak, M. N., and Azoulay, L., The use of aspirin and the risk of mortality in patients with prostate cancer, J Urol, vol. 193, pp. 1220-5, 2015.
J. Assayag, Yin, H., Benayoun, S., Pollak, M. N., Suissa, S., and Azoulay, L., Androgen deprivation therapy and the risk of colorectal cancer in patients with prostate cancer, Cancer Causes Control, vol. 24, pp. 839-45, 2013.
J. L. Atkins, Delgado, J., Pilling, L. C., Bowman, K., Masoli, J. A. H., Kuchel, G. A., Ferrucci, L., and Melzer, D., Impact of Low Cardiovascular Risk Profiles on Geriatric Outcomes: Evidence From 421,000 Participants in Two Cohorts, J Gerontol A Biol Sci Med Sci, 2018.
R. W. Atkinson, Carey, I. M., Kent, A. J., van Staa, T. P., Anderson, H. R., and Cook, D. G., Long-term exposure to outdoor air pollution and the incidence of chronic obstructive pulmonary disease in a national English cohort, Occup Environ Med, vol. 72, pp. 42-8, 2015.
R. W. Atkinson, Carey, I. M., Kent, A. J., van Staa, T. P., Anderson, H. R., and Cook, D. G., Long-term exposure to outdoor air pollution and incidence of cardiovascular diseases, Epidemiology, vol. 24, pp. 44-53, 2013.
E. L. Axson, Bloom, C. I., and Quint, J. K., Nontuberculous mycobacterial disease managed within UK primary care, 2006-2016, Eur J Clin Microbiol Infect Dis, vol. 37, pp. 1795-1803, 2018.
E. L. Axson, Bual, N., Bloom, C. I., and Quint, J. K., Risk factors and secondary care utilisation in a primary care population with non-tuberculous mycobacterial disease in the UK, Eur J Clin Microbiol Infect Dis, 2018.
E. L. Axson, Sundaram, V., Bloom, C. I., Bottle, A., Cowie, M. R., and Quint, J. K., Temporal Trends in the Incidence of Heart Failure among Patients with COPD and Its Association with Mortality, Ann Am Thorac Soc, 2020.
L. Azoulay, Eberg, M., Benayoun, S., and Pollak, M., 5alpha-Reductase Inhibitors and the Risk of Cancer-Related Mortality in Men With Prostate Cancer, JAMA Oncol, vol. 1, pp. 314-20, 2015.
L. Azoulay, Dell'Aniello, S., Simon, T. A., Renoux, C., and Suissa, S., Initiation of warfarin in patients with atrial fibrillation: early effects on ischaemic strokes, Eur Heart J, vol. 35, pp. 1881-7, 2014.
L. Azoulay, Schneider-Lindner, V., Dell'Aniello, S., Filion, K. B., and Suissa, S., Thiazolidinediones and the risk of incident strokes in patients with type 2 diabetes: a nested case-control study, Pharmacoepidemiol Drug Saf, vol. 19, pp. 343-50, 2010.
L. Azoulay, Dell'Aniello, S., Simon, T. A., Langleben, D., Renoux, C., and Suissa, S., A net clinical benefit analysis of warfarin and aspirin on stroke in patients with atrial fibrillation: a nested case-control study, BMC Cardiovasc Disord, vol. 12, p. 49, 2012.
[Page last reviewed 5 May 2020]