Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 3,500 peer-reviewed publications. The CPRD bibliography listed below is updated on a monthly basis (last updated 4 April 2024).

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

Download: CPRD bibliography PDF March 2024 (PDF, 4.2MB, 313 pages) 

Download: CPRD bibliography .BIB April 2024 (BIB, 1.3MB, 1 page)

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website

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Year Sort ascending Title
2021

Utilization and long-term persistence of direct oral anticoagulants among patients with non-valvular atrial fibrillation and liver disease

10.1111/bcp.15046

Authors: A. Douros, Y. Cui, R. Platt, K. Filion, G. Sebastiani, C. Renoux

2021

The Utilization and Safety of Umeclidinium and Umeclidinium/Vilanterol in UK Primary Care: A Retrospective Cohort Study

10.2147/copd.s291931

Authors: G. Requena, D. Dedman, J. Quint, R. Ghosh, R. Williams, J. Pimenta

2021

Validity of an algorithm to identify cardiovascular deaths from administrative health records: a multi-database population-based cohort study

10.1186/s12913-021-06762-0

Authors: L. Lix, S. Sobhan, A. St-Jean, J. Daigle, A. Fisher, O. H. Y. Yu, S. Dell'Aniello, N. Hu, S. Bugden, B. Shah, P. Ronksley, S. Alessi-Severini, A. Douros, P. Ernst, K. Filion

2021

Validity of bariatric surgery codes in the UK Clinical Practice Research Datalink (CPRD) GOLD compared with Hospital Episodes Statistics

10.1002/pds.5221

Authors: T. Burkard, M. Rauch, S. Jick, C. Meier

2021

Vertebral fracture as a risk factor for self-harm: a retrospective cohort study

10.1186/s12891-021-04631-9

Authors: J. Prior, F. Crawford-Manning, R. Whittle, A. Abdul-Sultan, C. Chew-Graham, S. Muller, T. Shepherd, A. Sumathipala, C. Mallen, Z. Paskins

2021

Weight change, cardio-metabolic risk factors and cardiovascular incidence in people with serious mental illness: protocol of a population-based cohort study in the UK from 1998 to 2020

10.1136/bmjopen-2021-053427

Authors: C. Lee, F. Waite, M. Smith, M. Gao, C. Bankhead, P. Aveyard, C. Piernas

2021

wEight chanGes, caRdio-mEtabolic risks and morTality in patients with hyperthyroidism (EGRET): a protocol for a CPRD-HES linked cohort study

10.1136/bmjopen-2021-055219

Authors: B. Torlinska, J. Hazlehurst, K. Nirantharakumar, G. Thomas, J. Priestley, S. Finnikin, P. Saunders, K. Abrams, K. Boelaert

2021

Weight loss and risk reduction of obesity-related outcomes in 0.5 million people: evidence from a UK primary care database

10.1038/s41366-021-00788-4

Authors: C. Haase, S. Lopes, A. Olsen, A. Satylganova, V. Schnecke, P. McEwan

2021

What is the incidence of methotrexate or leflunomide discontinuation related to cytopenia, liver enzyme elevation or kidney function decline?

10.1093/rheumatology/keab254

Authors: G. Nakafero, M. Grainge, T. Card, C. Mallen, W. Zhang, M. Doherty, M. Taal, G. Aithal, A. Abhishek

2021

Women with Polycystic Ovary Syndrome have an increased risk of major cardiovascular events: a population study

10.1210/clinem/dgab392

Authors: T. Berni, C. Morgan, D. Rees

2021

Younger people with rheumatoid arthritis are at increased risk of fracture even before age 50 years: a population-based cohort study

10.1007/s00198-021-05862-1

Authors: J. Erwin, D. Enki, A. Woolf

2021

β-blocker prescription is associated with lower cumulative risk of knee osteoarthritis and knee pain consultations in primary care: a propensity score matched cohort study

10.1093/rheumatology/keab234

Authors: G. Nakafero, M. Grainge, A. Valdes, N. Townsend, C. Mallen, W. Zhang, M. Doherty, M. Mamas, A. Abhishek

2021

Influence of the first wave of COVID-19 on asthma inhaler prescriptions

10.1038/s41533-021-00260-w

Authors: C. Bloom, E. Wong, K. Hickman, S. Elkin

2021

Estimation of age of transition from paediatric to adult healthcare for young people with long term conditions using linked routinely collected healthcare data

10.23889/ijpds.v6i1.1685

Authors: S. Jarvis, G. Richardson, K. Flemming, L. Fraser

2021

Effectiveness and safety among direct oral anticoagulants in nonvalvular atrial fibrillation: A multi-database cohort study with meta-analysis

10.1111/bcp.14669

Authors: M. Durand, M. Schnitzer, M. Pang, G. Carney, S. Eltonsy, K. Filion, A. Fisher, M. Jun, I. Kuo, A. Matteau, J. Paterson, J. Quail, C. Renoux

2021

Healthcare, Medication Utilization and Outcomes of Patients with COPD by GOLD Classification in England

10.2147/copd.s318969

Authors: L. Sansbury, K. Rothnie, C. Bains, C. Compton, G. Anley, A. Ismaila

2021

Persistence of Eosinophilic Asthma Endotype and Clinical Outcomes: A Real-World Observational Study

10.2147/jaa.s306416

Authors: T. Tran, M. Kerkhof, V. Carter, D. Price

2021

Lower cardiorenal risk with sodium-glucose cotransporter-2 inhibitors versus dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes without cardiovascular and renal diseases: A large multinational observational study

10.1111/dom.14189

Authors: K. Birkeland, J. Bodegard, A. Banerjee, D. Kim, A. Norhammar, J. Eriksson, M. Thuresson, S. Okami, K. Ha, N. Kossack, J. Mamza, R. Zhang, T. Yajima, I. Komuro, T. Kadowaki

2021

Lower risk of hospitalization for heart failure, kidney disease and death with sodium-glucose co-transporter-2 inhibitors compared with dipeptidyl peptidase-4 inhibitors in type 2 diabetes regardless of prior cardiovascular or kidney disease

10.1111/dom.14437

Authors: I. Idris, R. Zhang, J. Mamza, M. Ford, T. Morris, A. Banerjee, K. Khunti

2021

Suicide and other causes of death among working-age and older adults in the year after discharge from in-patient mental healthcare in England: matched cohort study

10.1192/bjp.2021.176

Authors: R. Musgrove, M. Carr, N. Kapur, C. Chew-Graham, F. Mughal, D. Ashcroft, R. Webb

2021

The healthcare resource impact of maternal mental illness on children and adolescents: UK retrospective cohort study

10.1192/bjp.2021.65

Authors: H. Hope, C. Osam, E. Kontopantelis, S. Hughes, L. Munford, D. Ashcroft, M. Pierce, K. Abel

2021

The Long-Term Impact of Vaginal Surgical Mesh Devices in UK Primary Care: A Cohort Study in the Clinical Practice Research Datalink

10.2147/clep.s333775

Authors: E. McFadden, S. Lay-Flurrie, C. Koshiaris, G. Richards, C. Heneghan

2021

Healthcare resource use and costs for people with type 2 diabetes mellitus with and without severe mental illness in England: longitudinal matched-cohort study using the Clinical Practice Research Datalink

10.1192/bjp.2021.131

Authors: H. Wang, L. Han, R. Jacobs, T. Doran, R. Holt, S. Prady, S. Gilbody, D. Shiers, S. Alderson, C. Hewitt, J. Taylor, C. Kitchen, S. Bellass, N. Siddiqi

2021

Does pre-existing morbidity influences risks and benefits of total hip replacement for osteoarthritis: a prospective study of 6682 patients from linked national datasets in England

10.1136/bmjopen-2020-046712

Authors: R. Ferguson, D. Prieto-Alhambra, G. Peat, A. Delmestri, K. Jordan, V . Y. Strauss, J. Valderas, C. Walker, D. Yu, S. Glyn-Jones, A. Silman

2021

Associations between attainment of incentivized primary care indicators and incident sight-threatening diabetic retinopathy in England: A population-based historical cohort study

10.1111/dom.14344

Authors: A. McKay, L. Gunn, M. Nugawela, T. Sathish, A. Majeed, Vamos E, G. Molina, S. Sivaprasad

2021

Does pre-existing morbidity influences risks and benefits of total hip replacement for osteoarthritis: a prospective study of 6682 patients from linked national datasets in England

10.1136/bmjopen-2020-046712

Authors: R. Ferguson, D. Prieto-Alhambra, G. Peat, A. Delmestri, K. Jordan, V . Y. Strauss, J. Valderas, C. Walker, D. Yu, S. Glyn-Jones, A. Silman

2021

Sodium-Glucose Cotransporter-2 Inhibitors and Urinary Tract Infections: A Propensity Score-matched Population-based Cohort Study

10.1016/j.jcjd.2021.12.005

Authors: W. Alkabbani, A. Zongo, J. Minhas-Sandhu, D. Eurich, B. Shah, M. Alsabbagh, J. Gamble

2020

Ability of primary care health databases to assess medicinal products discussed by the European Union Pharmacovigilance Risk Assessment Committee

10.1002/cpt.1775

Authors: R. Flynn, K. Hedenmalm, T. Murray-Thomas, A. Pacurariu, P. Arlett, H. Shepherd, P. Myles, X. Kurz

2020

Accelerated FEV(1) decline and risk of cardiovascular disease and mortality in a primary care population of COPD patients

10.1183/13993003.00918-2020

Authors: H. Whittaker, C. Bloom, A. Morgan, D. Jarvis, S. Kiddle, J. Quint

2020

Stopping renin-angiotensin system blockers after acute kidney injury and risk of adverse outcomes: parallel population-based cohort studies in English and Swedish routine care

10.1186/s12916-020-01659-x

Authors: P. Bidulka, E. Fu, C. Leyrat, F. Kalogirou, K. McAllister, E. Kingdon, K. Mansfield, M. Iwagami, L. Smeeth, C. Clase, K. Bhaskaran, M. van Diepen, J. Carrero, D. Nitsch, L. Tomlinson

2020

Targeted estimation of heterogeneous treatment effect in observational survival analysis

10.1016/j.jbi.2020.103474

Authors: J. Zhu, B. Gallego

2020

Temporal trends in incidence of atrial fibrillation in primary care records: a population-based cohort study

10.1136/bmjopen-2020-042518

Authors: S. Mendonca, C. Saunders, J. Lund, J. Mant, D. Edwards

2020

Temporal Trends in the Incidence of Heart Failure among Patients with COPD and Its Association with Mortality

10.1513/AnnalsATS.201911-820OC

Authors: E. Axson, V. Sundaram, C. Bloom, A. Bottle, M. Cowie, J. Quint

2020

Time trends and prescribing patterns of opioid drugs in UK primary care patients with non-cancer pain: A retrospective cohort study

10.1371/journal.pmed.1003270

Authors: M. Jani, Birlie Yimer, T. Sheppard, M. Lunt, W. Dixon

2020

Trajectories of Disease Accumulation Using Electronic Health Records

10.3233/shti200204

Authors: P. Planell-Morell, M. Bajekal, S. Denaxas, R. Raine, D. Alexander

2020

Treatment patterns among non-active users of maintenance asthma medication in the United Kingdom: a retrospective cohort study in the Clinical Practice Research Datalink

10.1080/02770903.2020.1728767

Authors: D. Gibbons, B. Aggarwal, J. Fairburn-Beech, D. Hinds, M. Fletcher, S. Bosnic-Anticevich, D. Price

2020

Trends in the pharmacological treatment of benign prostatic hyperplasia in the UK from 1998 to 2016: a population-based cohort study

10.1007/s00345-020-03429-z

Authors: H. Ayele, P. Reynier, L. Azoulay, R. Platt, J. Cabaussel, S. Benayoun, K. Filion

2020

Trends in time to cancer diagnosis around the period of changing national guidance on referral of symptomatic patients: A serial cross-sectional study using UK electronic healthcare records from 2006-17

10.1016/j.canep.2020.101805

Authors: S. Price, A. Spencer, X. Zhang, S. Ball, G. Lyratzopoulos, R. Mujica-Mota, S. Stapley, O. Ukoumunne, W. Hamilton

2020

The use of 5-aminosalicylates in Crohn\textquoterights disease: a retrospective study using the UK Clinical Practice Research Datalink

10.20524/aog.2020.0521

Authors: A. Hart, S. Ng, J. Watkins, K. Paridaens, J. Edwards, J. Fullarton, Y. L. Y. Sonderegger, O. Ghatnekar, S. Ghosh

2020

Use of antibiotics and asthma medication for acute lower respiratory tract infections in people with and without asthma: retrospective cohort study

10.1186/s12931-019-1233-5

Authors: R. Denholm, E. van der Werf, A. Hay

2020

Use of hormone replacement therapy and risk of breast cancer: nested case-control studies using the QResearch and CPRD databases

10.1136/bmj.m3873

Authors: Y. Vinogradova, C. Coupland, J. Hippisley-Cox

2020

Use of Hydrochlorothiazide and Risk of Melanoma and Nonmelanoma Skin Cancer

10.1007/s40264-020-01015-1

Authors: J. Rouette, H. Yin, A. Pottegard, K. Nirantharakumar, L. Azoulay

2020

Use of Sodium-Glucose Co-Transporter-2-Inhibitors (SGLT2-Is) and Risk of Lower Limb Amputation

10.2174/1574886315666200805103053

Authors: N. Werkman, J. Nielen, J. van den Bergh, N. Ejskjaer, J. R\oikjer, N. Schaper, B. Rossi, O. Klungel, P. Vestergaard, F. de Vries, J. Driessen

2020

Validation of cardiovascular outcomes and risk factors in the Clinical Practice Research Datalink in the United Kingdom

10.1002/pds.5150

Authors: A. Arana, A. Margulis, C. Varas-Lorenzo, C. Bui, A. Gilsenan, L. McQuay, M. Reynolds, C. Rebordosa, B. Franks, S. de Vogel, K. Appenteng, S. Perez-Gutthann

2020

Validation study of bullous pemphigoid and pemphigus vulgaris recording in routinely collected electronic primary healthcare records in England

10.1136/bmjopen-2019-035934

Authors: M. Persson, K. Harman, Y. Vinogradova, S. Langan, J. Hippisley-Cox, K. Thomas, S. Gran

2020

Varenicline versus nicotine replacement therapy for long-term smoking cessation: an observational study using the Clinical Practice Research Datalink

10.3310/hta24090

Authors: N. Davies, A. Taylor, G. Taylor, T. Itani, T. Jones, R. Martin, M. Munafo, F. Windmeijer, K. Thomas

2020

Variation in the Association between Antineoplastic Therapies and Venous Thromboembolism in Patients with Active Cancer

10.1055/s-0040-1709527

Authors: M. Giustozzi, A. Curcio, B. Weijs, T. Field, S. Sudikas, A. Katholing, C. Wallenhorst, J. Weitz, C. Martinez, A. Cohen

2020

Weight-lowering effects of glucagon-like peptide-1 receptor agonists and detection of breast cancer among obese women with diabetes

10.1097/ede.0000000000001196

Authors: C. Santella, H. Yin, B. Hicks, O. H. Y. Yu, N. Bouganim, L. Azoulay

2020

What are the implications of using individual and combined sources of routinely collected data to identify and characterise incident site-specific cancers? a concordance and validation study using linked English electronic health records data

10.1136/bmjopen-2020-037719

Authors: H. Strongman, R. Williams, K. Bhaskaran

2020

What is the optimal blood pressure level for patients with atrial fibrillation treated with direct oral anticoagulants?

10.1097/hjh.0000000000002487

Authors: J. Minhas, B. Coles, A. Mistri, D. Eveson, S. Hussain, J. Potter, K. Khunti, T. Robinson