2023 |
Incidence, prevalence, and co-occurrence of autoimmune disorders over time and by age, sex, and socioeconomic status: a population-based cohort study of 22 million individuals in the UK
10.1016/s0140-6736(23)00457-9
Authors: N. Conrad, S. Misra, J . Y. Verbakel, G. Verbeke, G. Molenberghs, P. Taylor, J. Mason, N. Sattar, J. McMurray, I. McInnes, K. Khunti, G. Cambridge |
2023 |
Identifying subtypes of heart failure from three electronic health record sources with machine learning: an external, prognostic, and genetic validation study
10.1016/s2589-7500(23)00065-1
Authors: A. Banerjee, A. Dashtban, S. Chen, L. Pasea, J. Thygesen, G. Fatemifar, B. Tyl, T. Dyszynski, F. Asselbergs, L. Lund, T. Lumbers, S. Denaxas, H. Hemingway |
2023 |
Fertility Trends and Adverse Pregnancy Outcomes in Female Patients With Psoriasis in the UK
10.1001/jamadermatol.2023.1400
Authors: T. Chen, I. Iskandar, R. Parisi, M. Pierce, C. Tower, C. Kleyn, C. Griffiths, D. Ashcroft |
2023 |
Short-acting β(2)-agonists and exacerbations in children with asthma in England: SABINA Junior
10.1183/23120541.00571-2022
Authors: A. Morgan, E. Maslova, C. Kallis, I. Sinha, G. Roberts, T. Tran, R. van der Valk, J. Quint |
2023 |
Trends in musculoskeletal consultations and prescribing: an electronic primary care records study
10.3399/bjgp.2022.0648
Authors: Victoria Welsh, Kayleigh Mason, James Bailey, Ram Bajpai, Kelvin Jordan, Christian Mallen, Claire Burton |
2023 |
Inequalities in cancer screening participation between adults with and without severe mental illness: results from a cross-sectional analysis of primary care data on English Screening Programmes
10.1038/s41416-023-02249-3
Authors: R. Kerrison, A. Jones, J. Peng, G. Price, J. Verne, E. Barley, C. Lugton |
2023 |
Rates of adverse clinical events in patients with chronic kidney disease: analysis of electronic health records from the UK clinical practice research datalink linked to hospital data
10.1186/s12882-023-03119-z
Authors: D. Little, M. Arnold, K. Hedman, P. Sun, S. Haque, G. James |
2023 |
Improving 10-year cardiovascular risk prediction in apparently healthy people: flexible addition of risk modifiers on top of SCORE2
10.1093/eurjpc/zwad187
Authors: S. Hageman, C. Petitjean, L. Pennells, S. Kaptoge, R. Pajouheshnia, T. Tillmann, M. Blaha, R. McClelland, K. Matsushita, V. Nambi, O. Klungel, P. Souverein, Y. van der Schouw, W. Verschuren, N. Lehmann, R. Erbel, K. Jöckel, E. Di Angelantonio, F. Visseren, J. Dorresteijn |
2023 |
Pharmacologic heterogeneity and risk of severe hypoglycemia with concomitant use of sulfonylureas and DPP-4 inhibitors: population-based cohort study
10.1002/cpt.2975
Authors: J. Dimakos, Y. Cui, R. Platt, C. Renoux, K. Filion, A. Douros |
2023 |
Contemporary trends in the utilization of second-line pharmacological therapies for type 2 diabetes in the United States and the United Kingdom
10.1111/dom.15196
Authors: D. Abrahami, E. D'Andrea, H. Yin, S. Kim, J. Paik, D. Wexler, L. Azoulay, E. Patorno |
2023 |
Evaluation of common prescription analgesics and adjuvant analgesics as markers of suicide risk: a longitudinal population-based study in England
10.1016/j.lanepe.2023.100695
Authors: D. Alothman, E. Tyrrell, S. Lewis, T. Card, A. Fogarty |
2023 |
Comparison of causal forest and regression-based approaches to evaluate treatment effect heterogeneity: an application for type 2 diabetes precision medicine
10.1186/s12911-023-02207-2
Authors: A. Venkatasubramaniam, B. Mateen, B. Shields, A. Hattersley, A. Jones, S. Vollmer, J. Dennis |
2023 |
Real-world comparative effectiveness of three single-inhaler dual bronchodilators for the treatment of chronic obstructive pulmonary disease
10.1183/13993003.00538-2023
Authors: J. Li, S. Dell'Aniello, P. Ernst, S. Suissa |
2023 |
Recent trends in asthma diagnosis, preschool wheeze diagnosis and asthma exacerbations in English children and adolescents: a SABINA Jr study
10.1136/thorax-2022-219757
Authors: C. Kallis, E. Maslova, A. Morgan, I. Sinha, G. Roberts, R. van der Valk, J. Quint, T. Tran |
2023 |
Real-world evidence from the first online healthcare analytics platform-Livingstone. Validation of its descriptive epidemiology module
10.1371/journal.pdig.0000310
Authors: B. Heywood, C. Morgan, T. Berni, D. Summers, B. Jones, S. Jenkins-Jones, S. Holden, L. Riddick, H. Fisher, J. Bateman, C. Bannister, J. Threlfall, A. Buxton, C. Shepherd, E. Mathias, R. Thomason, E. Hubbuck, C. Currie |
2023 |
Pharmacologically Treated Anxiety and Depression in People Diagnosed with von Willebrand Disease: Matched Cohort Study
10.2147/jbm.s407993
Authors: K. Hagberg, S. Jick, G. Ozen, P. Du |
2023 |
Frequency and impact of medication reviews for people aged 65 years or above in UK primary care: an observational study using electronic health records
10.1186/s12877-023-04143-2
Authors: R. Joseph, R. Knaggs, C. Coupland, A. Taylor, Y. Vinogradova, D. Butler, L. Gerrard, D. Waldram, B. Iyen, R. Akyea, D. Ashcroft, A. Avery, R. Jack |
2023 |
Healthcare Resource Use and Costs Associated with Organ Damage in Newly Diagnosed Adults with Systemic Lupus Erythematosus in the UK
10.1007/s40744-023-00567-9
Authors: H. Stirnadel-Farrant, S. Golam, B. Naisbett-Groet, D. Gibson, J. Langham, S. Langham, M. Samnaliev |
2023 |
An algorithm-based approach to ascertain patients with rare diseases in electronic health records using hypereosinophilic syndrome as an example
10.1002/pds.5655
Authors: G. Requena, S. Joksaite, N. Galwey, R. Jakes |
2023 |
Prevalence and treatment patterns of adult atopic dermatitis in the UK Clinical Practice Research Datalink
10.1002/ski2.232
Authors: C. Kleyn, R. McKenzie, A. Meeks, B. Gittens, L. von Arx |
2023 |
Health economic impact of moderate-to-severe chronic pain associated with osteoarthritis in England: a retrospective analysis of linked primary and secondary care data
10.1136/bmjopen-2022-067545
Authors: G. Coates, P. Clewes, C. Lohan, H. Stevenson, R. Wood, T. Tritton, R. Knaggs, A. Dickson, D. Walsh |
2023 |
Independent Associations of Incident Epilepsy and Enzyme-Inducing and Non-Enzyme-Inducing Antiseizure Medications With the Development of Osteoporosis
10.1001/jamaneurol.2023.1580
Authors: C. Josephson, A. Gonzalez-Izquierdo, S. Denaxas, T. Sajobi, K. Klein, S. Wiebe |
2023 |
Stratification of diabetes in the context of comorbidities, using representation learning and topological data analysis
10.1038/s41598-023-38251-1
Authors: M. Wamil, A. Hassaine, S. Rao, Y. Li, M. Mamouei, D. Canoy, M. Nazarzadeh, Z. Bidel, E. Copland, K. Rahimi, G. Salimi-Khorshidi |
2023 |
Healthcare utilisation and mortality in people with osteoarthritis in the UK: findings from a national primary care database
10.3399/bjgp.2022.0419
Authors: S. Swain, C. Coupland, A. Sarmanova, C. Kuo, C. Mallen, M. Doherty, W. Zhang |
2023 |
Pre-diagnostic prescribing patterns in dyspnoea patients with as-yet-undiagnosed lung cancer: A longitudinal study of linked primary care and cancer registry data
10.1016/j.canep.2023.102429
Authors: B. Wickramasinghe, C. Renzi, M. Barclay, M. Callister, M. Rafiq, G. Lyratzopoulos |
2023 |
Temporal patterns in the recorded annual incidence of common mental disorders over two decades in the United Kingdom: a primary care cohort study
10.1017/s0033291723002349
Authors: J. Dykxhoorn, D. Osborn, K. Walters, J. Kirkbride, S. Gnani, A. Lazzarino |
2023 |
Changes to healthcare utilisation and symptoms for common mental health problems over the first 21 months of the COVID-19 pandemic: parallel analyses of electronic health records and survey data in England
10.1016/j.lanepe.2023.100697
Authors: V. Taxiarchi, M. Senior, D. Ashcroft, M. Carr, H. Hope, M. Hotopf, E. Kontopantelis, S. McManus, P. Patalay, S. Steeg, R. Webb, K. Abel, M. Pierce |
2023 |
Dementia risk in patients with type 2 diabetes: Comparing metformin with no pharmacological treatment
10.1002/alz.13349
Authors: B. Zheng, B. Su, S. Ahmadi-Abhari, D. Kapogiannis, I. Tzoulaki, E. Riboli, L. Middleton |
2023 |
Prevalence of Chronic Obstructive Pulmonary Disease in England from 2000 to 2019
10.2147/copd.s411739
Authors: P. Stone, M. Osen, A. Ellis, R. Coaker, J. Quint |
2023 |
Age at Type 2 Diabetes Diagnosis and Cause-Specific Mortality: Observational Study of Primary Care Patients in England
10.2337/dc23-0834
Authors: M. Barker, M. Davies, J. Sargeant, J. Chan, E. Gregg, S. Shabnam, K. Khunti, F. Zaccardi |
2023 |
Post-initiation predictors of discontinuation of the sodium-glucose cotransporter-2 inhibitors: A comparative cohort study from the United Kingdom
10.1111/dom.15241
Authors: W. Alkabbani, B. Shah, A. Zongo, D. Eurich, M. Alsabbagh, J. Gamble |
2023 |
Association Between Fluoroquinolone Use and Hospitalization With Aortic Aneurysm or Aortic Dissection
10.1001/jamacardio.2023.2418
Authors: J. Brown, K. Wing, C. Leyrat, S. Evans, K. Mansfield, A. Wong, L. Smeeth, N. Galwey, I. Douglas |
2023 |
Duration of Type 2 Diabetes and Incidence of Cancer: An Observational Study in England
10.2337/dc23-1013
Authors: F. Zaccardi, S. Ling, K. Brown, M. Davies, K. Khunti |
2023 |
Progression of stroke risk in patients aged <65 years diagnosed with atrial fibrillation: a cohort study in general practice
10.3399/bjgp.2022.0568
Authors: S. Mendonca, D. Edwards, J. Lund, C. Saunders, J. Mant |
2023 |
Association of Different Prescribing Patterns for Oral Corticosteroids With Fracture Preventive Care Among Older Adults in the UK and Ontario
10.1001/jamadermatol.2023.2495
Authors: J. Matthewman, M. Tadrous, K. Mansfield, D. Thiruchelvam, D. Redelmeier, A. Cheung, I. Lega, D. Prieto-Alhambra, L. Cunliffe, A. Mulick, A. Henderson, S. Langan, A. Drucker |
2023 |
Incidence of 12 common cardiovascular diseases and subsequent mortality risk in the general population
10.1093/eurjpc/zwad192
Authors: C. Prugger, M. Perier, A. Gonzalez-Izquierdo, H. Hemingway, S. Denaxas, J. Empana |
2023 |
All-Cause, Cardiovascular and Respiratory Mortality in People with Type 2 Diabetes and Chronic Obstructive Pulmonary Disease (COPD) in England: A Cohort Study Using the Clinical Practice Research Datalink (CPRD)
10.2147/copd.s407085
Authors: A. Raslan, J. Quint, S. Cook |
2023 |
Bariatric Surgery and Incident Heart Failure: a Propensity Score Matched Nationwide Cohort Study
10.1016/j.ijcard.2023.01.086
Authors: L. Kostanjsek, M. Ardissino, O. Moussa, B. Rayes, R. Amin, P. Collins, S. Purkayastha |
2023 |
Is Vaccination Against COVID-19 Associated With Inflammatory Bowel Disease Flare? Self-Controlled Case Series Analysis Using the UK CPRD
10.14309/ajg.0000000000002205
Authors: T. Card, G. Nakafero, M. Grainge, C. Mallen, J. Van-Tam, H. Williams, A. Abhishek |
2023 |
Completeness, agreement, and representativeness of ethnicity recording in the United Kingdom's Clinical Practice Research Datalink (CPRD) and linked Hospital Episode Statistics (HES)
10.1186/s12963-023-00302-0
Authors: S. Shiekh, M. Harley, R. Ghosh, M. Ashworth, P. Myles, H. Booth, E. Axson |
2023 |
Treatment Patterns, Healthcare Utilization and Clinical Outcomes of Patients with Chronic Obstructive Pulmonary Disease Initiating Single-Inhaler Long-Acting β(2)-Agonist/Long-Acting Muscarinic Antagonist Dual Therapy in Primary Care in England
10.2147/copd.s389281
Authors: G. Requena, V. Banks, A. Czira, R. Wood, T. Tritton, R. Wild, C. Compton, A. Ismaila |
2023 |
Identifying subtypes of chronic kidney disease with machine learning: development, internal validation and prognostic validation using linked electronic health records in 350,067 individuals
10.1016/j.ebiom.2023.104489
Authors: A. Dashtban, M. Mizani, L. Pasea, S. Denaxas, R. Corbett, J. Mamza, H. Gao, T. Morris, H. Hemingway, A. Banerjee |
2023 |
Impact of the COVID-19 pandemic on incidence of tics in children and young people: a population-based cohort study
10.1016/j.eclinm.2023.101857
Authors: R. Jack, R. Joseph, C. Coupland, C. Hall, C. Hollis |
2023 |
Combined and progestagen-only hormonal contraceptives and breast cancer risk: A UK nested case-control study and meta-analysis
10.1371/journal.pmed.1004188
Authors: D. Fitzpatrick, K. Pirie, G. Reeves, J. Green, V. Beral |
2023 |
Twenty-year trajectories of cardio-metabolic factors among people with type 2 diabetes by dementia status in England: a retrospective cohort study
10.1007/s10654-023-00977-7
Authors: H. Lai, K. Chang, M. Sharabiani, J. Valabhji, E. Gregg, L. Middleton, A. Majeed, J. Pearson-Stuttard, C. Millett, A. Bottle, E. Vamos |
2023 |
Burden of Pertussis in Adults Aged 50 Years and Older: A Retrospective Database Study in England
10.1007/s40121-023-00774-5
Authors: L. Harrington, E. Aris, A. Bhavsar, N. Jamet, E. Akpo, J. Simeone, A. Ramond, D. Lambrelli, J. Oppenheimer, Y. Sergerie, P. Mukherjee, K. Meszaros |
2023 |
Contextualising adverse events of special interest to characterise the baseline incidence rates in 24 million patients with COVID-19 across 26 databases: a multinational retrospective cohort study
10.1016/j.eclinm.2023.101932
Authors: E. Voss, A. Shoaibi, Yin Lai, C. Blacketer, T. Alshammari, R. Makadia, K. Haynes, A. Sena, G. Rao, S. van Sandijk, C. Fraboulet, L. Boyer, T. Le Carrour, S. Horban, D. Morales, Martínez Roldán, J. Ramirez-Anguita, M. Mayer, M. de Wilde, L. John, T. Duarte-Salles, E. Roel, A. Pistillo, R. Kolde, F. Maljković, S. Denaxas, V. Papez, M. Kahn, K. Natarajan, C. Reich, A. Secora, E. Minty, N. Shah, J. Posada, M. Morales, D. Bosca, Cadenas Juanino, Diaz Holgado, Pedrera Jiménez, Serrano Balazote, García Barrio, S. Şen, A . Y. Üresin, B. Erdogan, L. Belmans, G. Byttebier, Mlng Malbrain, D. Dedman, Z. Cuccu, R. Vashisht, A. Butte, A. Patel, L. Dahm, C. Han, F. Bu, F. Arshad, A. Ostropolets, F. Nyberg, G. Hripcsak, M. Suchard, D. Prieto-Alhambra, P. Rijnbeek, M. Schuemie, P. Ryan |
2023 |
Trends in gabapentinoid prescribing in UK primary care using the Clinical Practice Research Datalink: an observational study
https://doi.org/10.1016/j.lanepe.2022.100579
Authors: Julie Ashworth, Ram Bajpai, Sara Muller, James Bailey, Toby Helliwell, Sarah Harrisson, Rebecca Whittle, Christian Mallen |
2023 |
Characterising the burden of chronic kidney disease among people with type 2 diabetes in England: a cohort study using the Clinical Practice Research Datalink
10.1136/bmjopen-2022-065927
Authors: S. Cook, N. Schmedt, J. Broughton, P. Kalra, L. Tomlinson, J. Quint |
2023 |
Prescribing of Low-dose Rivaroxaban in Patients with Atherosclerotic Cardiovascular Disease in the United Kingdom and the Netherlands
10.1111/bcp.15708
Authors: N. Hunt, R. Pajouheshnia, A. Salih, S. van Doorn, P. Souverein, M. Bazelier, O. Klungel, H. Gardarsdottir |