Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 3,000 peer-reviewed publications. The CPRD bibliography listed below is updated on a monthly basis (last updated 8 July 2022).

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.

Download: CPRD bibliography PDF July 2022 (PDF, 6MB, 267 pages) 

Download: CPRD bibliography .BIB July 2022 (BIB, 1.3MB, 1 page)

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website

Page last reviewed
Year Sort ascending Title

Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.3 million individuals


Authors: S. Chung, R. Providencia, R. Sofat, M. Pujades-Rodriguez, A. Torralbo, G. Fatemifar, N. Fitzpatrick, J. Taylor, K. Li, C. Dale, M. Rossor, D. Acosta-Mena, J. Whittaker, S. Denaxas


Oral bisphosphonates are associated with increased risk of severe acute kidney injury in elderly patients with complex health needs: a self-controlled case series in the UK


Authors: T. Oda, A. Jödicke, D. Robinson, A. Delmestri, R. Keogh, D. Prieto-Alhambra


Treatment Transitions in Chronic Obstructive Pulmonary Disease: Retrospective Analyses of US and UK Healthcare Databases


Authors: C. Bloom, J. Montonen, O. Jöns, E. Garry, S. Bhatt


Has the gout epidemic peaked in the UK? A nationwide cohort study using data from the Clinical Practice Research Datalink, from 1997 to across the COVID-19 pandemic in 2021


Authors: A. Abhishek, L. Tata, M. Mamas, A. Avery


Alcohol use recording in adults with depression in English primary care: a cross-sectional study


Authors: E. Adesanya, S. Cook, E. Crellin, S. Langan, K. Mansfield, L. Smeeth, E. Herrett


First Maintenance Therapy for Chronic Obstructive Pulmonary Disease: Retrospective Analyses of US and UK Healthcare Databases


Authors: C. Bloom, J. Montonen, O. Jöns, E. Garry, S. Bhatt


Transparency of high-dimensional propensity score analyses: guidance for diagnostics and reporting


Authors: J. Tazare, R. Wyss, J. Franklin, L. Smeeth, S. Evans, S. Wang, S. Schneeweiss, I. Douglas, J. Gagne, E. Williamson


The feasibility of pragmatic influenza vaccine randomized controlled real-world trials in Denmark and England


Authors: J. Nealon, D. Modin, R. Ghosh, D. Rudin, G. Gislason, H. Booth, J. Jensen, R. Williams, H. Shepherd, E. Yelland, H. Bricout, S. Chaves, T. Biering-Sørensen


Epidemiology of pre-existing multimorbidity in pregnant women in the UK in 2018: a population-based cross-sectional study


Authors: S. Lee, A. Azcoaga-Lorenzo, U. Agrawal, J. Kennedy, A. Fagbamigbe, H. Hope, A. Subramanian, A. Anand, B. Taylor, C. Nelson-Piercy, C. Damase-Michel, C. Yau, F. Crowe, G. Santorelli, K. Eastwood, Z. Vowles, M. Loane, N. Moss, P. Brocklehurst, R. Plachcinski, S. Thangaratinam, M. Black, D. O'Reilly, K. Abel, S. Brophy, K. Nirantharakumar, C. McCowan


Clustering of comorbidities and associated outcomes in people with osteoarthritis - A UK Clinical Practice Research Datalink study


Authors: S. Swain, C. Coupland, V. Strauss, C. Mallen, C. Kuo, A. Sarmanova, S. Bierma-Zeinstra, M. Englund, D. Prieto-Alhambra, M. Doherty, W. Zhang


Glucagon-Like Peptide 1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors and Risk of Nonalcoholic Fatty Liver Disease Among Patients With Type 2 Diabetes


Authors: R. Pradhan, H. Yin, O. Yu, L. Azoulay


Primary care clinical management following self-harm during the first wave of COVID-19 in the UK: population-based cohort study


Authors: S. Steeg, M. Carr, L. Trefan, D. Ashcroft, N. Kapur, E. Nielsen, B. McMillan, R. Webb


No evidence that herpes zoster is associated with increased risk of dementia diagnosis


Authors: C. Warren-Gash, E. Williamson, S. Shiekh, J. Borjas-Howard, N. Pearce, J. Breuer, L. Smeeth


Glucagon-Like Peptide-1 Receptor Agonists and Risk of Anaphylactic Reaction Among Patients With Type 2 Diabetes: Multisite Population-Based Cohort Study


Authors: R. Pradhan, E. Patorno, H. Tesfaye, S. Schneeweiss, H. Yin, J. Franklin, A. Pawar, C. Santella, O. H. Y. Yu, C. Renoux, L. Azoulay


Blood eosinophils to guide inhaled maintenance therapy in a primary care COPD population


Authors: H. Ashdown, M. Smith, E. McFadden, I. Pavord, C. Butler, M. Bafadhel


Antipsychotic treatment patterns in Alzheimer's disease patients with agitation: a cohort study using the UK clinical practice research datalink


Authors: C. Tran, M. Bøg, S. Collings, M. Johnson, N. Qizilbash, S. Lind, R. Baker, K. Jørgensen


Statin use is associated with lower risk of dementia in stroke patients: a community-based cohort study with inverse probability weighted marginal structural model analysis


Authors: Z. Yang, S. Toh, X. Li, D. Edwards, C. Brayne, J. Mant


Surgical treatment, complications, reoperations, and healthcare costs among patients with clavicle fracture in England


Authors: S. Wolf, A. Chitnis, A. Manoranjith, M. Vanderkarr, J. Plaza, L. Gador, C. Holy, C. Sparks, S. Lambert


Comparing antibiotic prescribing between clinicians in UK primary care: an analysis in a cohort study of eight different measures of antibiotic prescribing


Authors: T. Van Staa, Y. Li, N. Gold, T. Chadborn, W. Welfare, V. Palin, D. Ashcroft, J. Bircher


Characteristics of New Users of Aclidinium Bromide, Aclidinium/Formoterol, and Other COPD Medications in the United Kingdom, Denmark, and Germany


Authors: E. Rivero-Ferrer, M. Olesen, E. Plana, J. Aguado, N. Saigi-Morgui, A. Rubino, S. Daoud, A. Lei, S. Perez-Gutthann, T. Schink, N. Kristiansen, J. Hallas, A. Pottegard, C. Rebordosa


UK poSt Arthroplasty Follow-up rEcommendations (UK SAFE): what does analysis of linked, routinely collected national datasets tell us about mid-late term revision risk after knee replacement?


Authors: L. Smith, C. Garriga, S. Kingsbury, R. Pinedo-Villanueva, A. Delmestri, N. Arden, M. Stone, P. Conaghan, A. Judge


Screening for type 2 diabetes after a diagnosis of gestational diabetes by ethnicity: A retrospective cohort study


Authors: E. Vounzoulaki, K. Khunti, J. Miksza, B. Tan, M. Davies, C. Gillies


The risk of all-cause and cause-specific mortality in people prescribed mirtazapine: an active comparator cohort study using electronic health records


Authors: R. Joseph, R. Jack, R. Morriss, R. Knaggs, D. Butler, C. Hollis, J. Hippisley-Cox, C. Coupland


Reduction of Cardiovascular Disease and Mortality versus Risk of New Onset Diabetes with Statin Use in Patients with Rheumatoid Arthritis


Authors: G. Ozen, S. Dell'Aniello, S. Pedro, K. Michaud, S. Suissa


Real-world weight change, adherence, and discontinuation among patients with type 2 diabetes initiating glucagon-like peptide-1 receptor agonists in the UK


Authors: T. Weiss, L. Yang, R. Carr, S. Pal, B. Sawhney, R. Boggs, S. Rajpathak, K. Iglay


Primary Prevention of Cardiovascular and Heart Failure Events With SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Their Combination in Type 2 Diabetes


Authors: A. Wright, M. Carr, E. Kontopantelis, L. Leelarathna, H. Thabit, R. Emsley, I. Buchan, M. Mamas, T. van Staa, N. Sattar, D. Ashcroft, M. Rutter


Associations of Cardiovascular and Non-Cardiovascular Comorbidities with Dementia Risk in Patients with Diabetes: Results from a Large UK Cohort Study


Authors: B. Zheng, B. Su, C. Udeh-Momoh, G. Price, I. Tzoulaki, E. Vamos, A. Majeed, E. Riboli, S. Ahmadi-Abhari, L. Middleton


Assessing the severity of cardiovascular disease in 213 088 patients with coronary heart disease: a retrospective cohort study


Authors: S. Zghebi, M. Mamas, D. Ashcroft, M. Rutter, H. VanMarwijk, C. Salisbury, C. Mallen, C. Chew-Graham, N. Qureshi, S. Weng, T. Holt, I. Buchan, N. Peek, S. Giles, D. Reeves, E. Kontopantelis


Assessment of common infections and incident dementia using UK primary and secondary care data: a historical cohort study


Authors: R. Muzambi, K. Bhaskaran, L. Smeeth, C. Brayne, N. Chaturvedi, C. Warren-Gash


Associations between breast cancer survivorship and adverse mental health outcomes: A matched population-based cohort study in the United Kingdom


Authors: H. Carreira, R. Williams, G. Funston, S. Stanway, K. Bhaskaran


Asthma phenotyping in primary care: applying the International Severe Asthma Registry eosinophil phenotype algorithm across all asthma severities


Authors: M. Kerkhof, T. Tran, R. Allehebi, G. Canonica, L. Heaney, M. Hew, Perez de Llano, M. Wechsler, L. Bulathsinhala, V. Carter, I. Chaudhry, N. Eleangovan, R. Murray, C. Price, D. Price


Atopic eczema in adulthood and mortality: UK population-based cohort study, 1998-2016


Authors: R. Silverwood, K. Mansfield, A. Mulick, A. Wong, S. Schmidt, A. Roberts, L. Smeeth, K. Abuabara, S. Langan


A Cohort Study to Evaluate the Risk of Hospitalisation for Congestive Heart Failure Associated with the Use of Aclidinium and Other Chronic Obstructive Pulmonary Disease Medications in the UK Clinical Practice Research Datalink


Authors: C. Rebordosa, E. Plana, A. Rubino, J. Aguado, A. Lei, S. Daoud, N. Saigi-Morgui, S. Perez-Gutthann, E. Rivero-Ferrer


Comorbid diseases and conditions in people with HIV in the UK


Authors: B. Jones, A. Freedman, M. Thomas, C. Villalba-Mendez, L. Sathia, D. Flanagan, S. Francis, C. Currie


Comparative Effectiveness of Initial LAMA versus LABA in COPD: Real-World Cohort Study


Authors: S. Suissa, S. Dell'Aniello, P. Ernst


Comparing initial LABA-ICS inhalers in COPD: Real-world effectiveness and safety


Authors: S. Suissa, S. Dell'Aniello, P. Ernst


Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort


Authors: C. Dormuth, B. Winquist, A. Fisher, F. Wu, P. Reynier, S. Suissa, M. Dahl, Z. Ma, X. Lu, J. Zhang, C. Raymond, K. Filion, R. Platt, C. Moriello, J. Paterson


The Complex Association Between Bariatric Surgery and Depression: a National Nested-Control Study


Authors: C. Arhi, R. Dudley, O. Moussa, M. Ardissino, S. Scholtz, S. Purkayastha


Concordance and timing in recording cancer events in primary care, hospital and mortality records for patients with and without psoriasis: A population-based cohort study


Authors: A. Trafford, R. Parisi, M. Rutter, E. Kontopantelis, C. Griffiths, D. Ashcroft


Impact of COVID-19 restrictions on diabetes health checks and prescribing for people with type 2 diabetes: a UK-wide cohort study involving 618 161 people in primary care


Authors: M. Carr, A. Wright, L. Leelarathna, H. Thabit, N. Milne, N. Kanumilli, D. Ashcroft, M. Rutter


The Impact of Demographic, Socio-Economic and Geographic Factors on Mortality Risk among People Living with Dementia in England (2002-2016)


Authors: J. Watson, F. Darlington-Pollock, M. Green, C. Giebel, A. Akpan


Impact of influenza vaccination on amoxicillin prescriptions in older adults: A retrospective cohort study using primary care data


Authors: L. Rodgers, A. Streeter, N. Lin, W. Hamilton, W. Henley


The impact of severe mental illness on healthcare use and health outcomes for people with type 2 diabetes


Authors: L. Han, T. Doran, R. Holt, C. Hewitt, R. Jacobs, S. Prady, S. Alderson, D. Shiers, H. Wang, S. Bellass, S. Gilbody, C. Kitchen, J. Lister, J. Taylor, N. Siddiqi


Incidence and survival of haemophagocytic lymphohistiocytosis: A population-based cohort study from England


Authors: J. West, T. Card, M. Bishton, P. Lanyon, L. Ban, M. Bythell, L. Elliss-Brookes, J. Manson, V. Nanduri, J. Rankin, R. Tattersall, C. Crooks


Incidence, hospitalization and mortality and their changes over time in people with a first ever diabetic foot ulcer


Authors: J. R\oikjer, N. Werkman, N. Ejskjaer, J. van den Bergh, P. Vestergaard, N. Schaper, M. Jensen, O. Klungel, F. de Vries, J. Nielen, J. Driessen, N. Ejskjaer, J. van den Bergh, P. Vestergaard, N. Schaper, Hasselstr\om Jensen, O. Klungel, F. de Vries, J. Nielen, J. Driessen, F. de Vries


Increased mortality risk in patients with primary and secondary adrenal insufficiency


Authors: K. Ngaosuwan, D. Johnston, I. Godsland, J. Cox, A. Majeed, J. Quint, N. Oliver, S. Robinson


The increasing incidence and prevalence of hypereosinophilic syndrome in the United Kingdom


Authors: G. Requena, J. Logie, D. Gibbons, J. Steinfeld, M. Van Dyke


Incretin-Based Drugs and Risk of Intestinal Obstruction Among Patients with Type 2 Diabetes


Authors: J. Faillie, H. Yin, O. H. Y. Yu, A. Herrero, R. Altwegg, C. Renoux, L. Azoulay


Indirect acute effects of the COVID-19 pandemic on physical and mental health in the UK: a population-based study


Authors: K. Mansfield, R. Mathur, J. Tazare, A. Henderson, A. Mulick, H. Carreira, A. Matthews, P. Bidulka, A. Gayle, H. Forbes, S. Cook, A. Wong, H. Strongman, K. Wing, C. Warren-Gash, S. Cadogan, L. Smeeth, J. Hayes, J. Quint, M. McKee, S. Langan


Inequalities in incident and prevalent multimorbidity in England, 2004\textendash19: a population-based, descriptive study


Authors: A. Head, K. Fleming, C. Kypridemos, P. Schofield, J. Pearson-Stuttard, M. O\textquoterightFlaherty