Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,700 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 4 May 2021) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 5MB, 226 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



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F. de Vries, van Staa, T. P., Bracke, M. S., Cooper, C., Leufkens, H. G., and Lammers, J. W., Severity of obstructive airway disease and risk of osteoporotic fracture, Eur Respir J, vol. 25, pp. 879-84, 2005.
F. de Vries, de Vries, C., Cooper, C., Leufkens, B., and van Staa, T. P., Reanalysis of two studies with contrasting results on the association between statin use and fracture risk: the General Practice Research Database, Int J Epidemiol, vol. 35, pp. 1301-8, 2006.
F. de Vries, Bracke, M., Leufkens, H. G., Lammers, J. W., Cooper, C., and van Staa, T. P., Fracture risk with intermittent high-dose oral glucocorticoid therapy, Arthritis Rheum, vol. 56, pp. 208-14, 2007.
F. de Vries, Souverein, P. C., Cooper, C., Leufkens, H. G., and van Staa, T. P., Use of beta-blockers and the risk of hip/femur fracture in the United Kingdom and The Netherlands, Calcif Tissue Int, vol. 80, pp. 69-75, 2007.
F. de Vries, Cooper, A. L., Cockle, S. M., van Staa, T. P., and Cooper, C., Fracture risk in patients receiving acid-suppressant medication alone and in combination with bisphosphonates, Osteoporos Int, vol. 20, pp. 1989-98, 2009.
F. de Vries, Setakis, E., and van Staa, T. P., Concomitant use of ibuprofen and paracetamol and the risk of major clinical safety outcomes, Br J Clin Pharmacol, vol. 70, pp. 429-38, 2010.
F. de Vries, Setakis, E., Zhang, B., and van Staa, T. P., Long-acting {beta}2-agonists in adult asthma and the pattern of risk of death and severe asthma outcomes: a study using the GPRD, Eur Respir J, vol. 36, pp. 494-502, 2010.
[Page last reviewed 4 May 2021]