Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 3,000 peer-reviewed publications. The CPRD bibliography listed below is updated on a monthly basis (last updated 8 August 2022).

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.

Download: CPRD bibliography PDF August 2022 (PDF, 6MB, 271 pages) 

Download: CPRD bibliography .BIB August 2022 (BIB, 1.3MB, 1 page)

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website

Page last reviewed
Year Sort ascending Title

Adverse outcomes after partner bereavement in people with reduced kidney function: Parallel cohort studies in England and Denmark


Authors: P. Bidulka, S. Vestergaard, A. Hlupeni, A. Kjaersgaard, A. Wong, S. Langan, S. Schmidt, S. Lyon, C. Christiansen, D. Nitsch


All-Cause and Cardiovascular Mortality Among Insulin-Naïve People With Type 2 Diabetes Treated With Insulin Detemir or Glargine: A Cohort Study in the UK


Authors: L. Husemoen, L. M\orch, P. Christensen, N. Hartvig, M. Feher


Assessing the severity of cardiovascular disease in 213 088 patients with coronary heart disease: a retrospective cohort study


Authors: S. Zghebi, M. Mamas, D. Ashcroft, M. Rutter, H. VanMarwijk, C. Salisbury, C. Mallen, C. Chew-Graham, N. Qureshi, S. Weng, T. Holt, I. Buchan, N. Peek, S. Giles, D. Reeves, E. Kontopantelis


Assessment of common infections and incident dementia using UK primary and secondary care data: a historical cohort study


Authors: R. Muzambi, K. Bhaskaran, L. Smeeth, C. Brayne, N. Chaturvedi, C. Warren-Gash


Associations between attainment of incentivised primary care diabetes indicators and mortality in an English cohort


Authors: A. McKay, L. Gunn, E. Vamos, J. Valabhji, G. Molina, M. Molokhia, A. Majeed


Associations between attainment of incentivised primary care indicators and emergency hospital admissions among type 2 diabetes patients: a population-based historical cohort study


Authors: L. Gunn, A. McKay, M. Molokhia, J. Valabhji, G. Molina, A. Majeed, E. Vamos


Associations between breast cancer survivorship and adverse mental health outcomes: A matched population-based cohort study in the United Kingdom


Authors: H. Carreira, R. Williams, G. Funston, S. Stanway, K. Bhaskaran


Asthma phenotyping in primary care: applying the International Severe Asthma Registry eosinophil phenotype algorithm across all asthma severities


Authors: M. Kerkhof, T. Tran, R. Allehebi, G. Canonica, L. Heaney, M. Hew, Perez de Llano, M. Wechsler, L. Bulathsinhala, V. Carter, I. Chaudhry, N. Eleangovan, R. Murray, C. Price, D. Price


Atopic eczema in adulthood and mortality: UK population-based cohort study, 1998-2016


Authors: R. Silverwood, K. Mansfield, A. Mulick, A. Wong, S. Schmidt, A. Roberts, L. Smeeth, K. Abuabara, S. Langan


Atopic-eczema-associated fracture risk and oral corticosteroids: a population-based cohort study


Authors: J. Matthewman, K. Mansfield, D. Prieto-Alhambra, A. Mulick, L. Smeeth, K. Lowe, R. Silverwood, S. Langan


Atrial fibrillation epidemiology, disparity and healthcare contacts: a population-wide study of 5.6 million individuals


Authors: S. Chung, R. Sofat, D. Acosta-Mena, J. Taylor, P. Lambiase, J. Casas, R. Providencia


Changes in ankylosing spondylitis incidence, prevalence and time to diagnosis over two decades


Authors: S. Crossfield, H. Marzo-Ortega, S. Kingsbury, M. Pujades-Rodriguez, P. Conaghan


Changes in the pharmacological management of rheumatoid arthritis over two decades


Authors: S. Crossfield, M. Buch, P. Baxter, S. Kingsbury, M. Pujades-Rodriguez, P. Conaghan


Characterising the background incidence rates of adverse events of special interest for covid-19 vaccines in eight countries: multinational network cohort study


Authors: X. Li, A. Ostropolets, R. Makadia, A. Shoaibi, A. Rao, A. Sena, E. Martinez-Hernandez, K. Verhamme, P. Rijnbeek, P.B. Ryan, D. Prieto-Alhambra


Characterization and Associated Costs of Constipation Relating to Exposure to Strong Opioids in England: An Observational Study


Authors: C. Morgan, S. Jenkins-Jones, R. Knaggs, C. Currie, P. Conway, C. Poole, E. Berni


Clinical features and diagnosis of multiple myeloma: a population-based cohort study in primary care


Authors: A. Seesaghur, N. Petruski-Ivleva, V. Banks, J. Wang, A. Abbasi, D. Neasham, K. Ramasamy


A Cohort Study to Evaluate the Risk of Hospitalisation for Congestive Heart Failure Associated with the Use of Aclidinium and Other Chronic Obstructive Pulmonary Disease Medications in the UK Clinical Practice Research Datalink


Authors: C. Rebordosa, E. Plana, A. Rubino, J. Aguado, A. Lei, S. Daoud, N. Saigi-Morgui, S. Perez-Gutthann, E. Rivero-Ferrer


Comorbid diseases and conditions in people with HIV in the UK


Authors: B. Jones, A. Freedman, M. Thomas, C. Villalba-Mendez, L. Sathia, D. Flanagan, S. Francis, C. Currie


Comparative differences in musculoskeletal pain consultation and analgesic prescription for people with dementia: a UK-wide matched cohort study


Authors: L. Bullock, J. Bedson, Y. Chen, C. Chew-Graham, P. Campbell


Comparative Effectiveness of Initial LAMA versus LABA in COPD: Real-World Cohort Study


Authors: S. Suissa, S. Dell'Aniello, P. Ernst


Comparing initial LABA-ICS inhalers in COPD: Real-world effectiveness and safety


Authors: S. Suissa, S. Dell'Aniello, P. Ernst


Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort


Authors: C. Dormuth, B. Winquist, A. Fisher, F. Wu, P. Reynier, S. Suissa, M. Dahl, Z. Ma, X. Lu, J. Zhang, C. Raymond, K. Filion, R. Platt, C. Moriello, J. Paterson


The Complex Association Between Bariatric Surgery and Depression: a National Nested-Control Study


Authors: C. Arhi, R. Dudley, O. Moussa, M. Ardissino, S. Scholtz, S. Purkayastha


Concordance and timing in recording cancer events in primary care, hospital and mortality records for patients with and without psoriasis: A population-based cohort study


Authors: A. Trafford, R. Parisi, M. Rutter, E. Kontopantelis, C. Griffiths, D. Ashcroft


Persistence of Eosinophilic Asthma Endotype and Clinical Outcomes: A Real-World Observational Study


Authors: T. Tran, M. Kerkhof, V. Carter, D. Price


Glycemic Control, Diabetic Complications, and Risk of Dementia in Patients With Diabetes: Results From a Large U.K. Cohort Study


Authors: B. Zheng, B. Su, G. Price, I. Tzoulaki, S. Ahmadi-Abhari, L. Middleton


GP consultation rates for sequelae after acute covid-19 in patients managed in the community or hospital in the UK: population based study


Authors: H. Whittaker, C. Gulea, A. Koteci, C. Kallis, A. Morgan, C. Iwundu, M. Weeks, R. Gupta, J. Quint


Health Services and Delivery Research


Authors: M. Gulliford, J. Charlton, O. Boiko, J. Winter, E. Rezel-Potts, X. Sun, C. Burgess, L. McDermott, C. Bunce, J. Shearer, V. Curcin, R. Fox, A. Hay, P. Little, M. Moore, M. Ashworth


Health Services and Delivery Research


Authors: J. Lister, L. Han, S. Bellass, J. Taylor, S. Alderson, T. Doran, S. Gilbody, C. Hewitt, R. Holt, R. Jacobs, C. Kitchen, S. Prady, J. Radford, J. Ride, D. Shiers, H. Wang, N. Siddiqi


The healthcare resource impact of maternal mental illness on children and adolescents: UK retrospective cohort study


Authors: H. Hope, C. Osam, E. Kontopantelis, S. Hughes, L. Munford, D. Ashcroft, M. Pierce, K. Abel


Healthcare resource use and costs for people with type 2 diabetes mellitus with and without severe mental illness in England: longitudinal matched-cohort study using the Clinical Practice Research Datalink


Authors: H. Wang, L. Han, R. Jacobs, T. Doran, R. Holt, S. Prady, S. Gilbody, D. Shiers, S. Alderson, C. Hewitt, J. Taylor, C. Kitchen, S. Bellass, N. Siddiqi


Health-care utilization and costs in adults with systemic lupus erythematosus in the United Kingdom: a real-world observational retrospective cohort analysis


Authors: M. Samnaliev, V. Barut, S. Weir, J. Langham, S. Langham, X. Wang, B. Desta, E. Hammond


Identification and Validation of Major Cardiovascular Events in the United Kingdom Data Sources Included in a Multi-database Post-authorization Safety Study of Prucalopride


Authors: A. Ruigomez, E. Plana, A. Gilsenan, J. Fortuny, M. Cainzos-Achirica, R. Flynn, T. MacDonald, L. Garcia-Rodriguez, R. Ziemiecki, E. Andrews


Identifying adults at high-risk for change in weight and BMI in England: a longitudinal, large-scale, population-based cohort study using electronic health records


Authors: M. Katsoulis, A. Lai, K. Diaz-Ordaz, M. Gomes, L. Pasea, A. Banerjee, S. Denaxas, K. Tsilidis, P. Lagiou, G. Misirli, K. Bhaskaran, G. Wannamethee, R. Dobson, R. Batterham, D. Kipourou, R. Lumbers, L. Wen, N. Wareham, C. Langenberg, H. Hemingway


Identifying and evaluating clinical subtypes of Alzheimer\textquoterights disease in care electronic health records using unsupervised machine learning


Authors: N. Alexander, D. Alexander, F. Barkhof, S. Denaxas


Impact of changes to national guidelines on hypertension-related workload: an interrupted time series analysis in English primary care


Authors: S. Lay-Flurrie, J. Sheppard, R. Stevens, C. Mallen, C. Heneghan, F. Hobbs, B. Williams, J. Mant, R. McManus


The impact of changing risk thresholds on the number of people in England eligible for urgent investigation for possible cancer: an observational cross-sectional study


Authors: S. Moore, S. Price, S. Chowienczyk, J. Bostock, W. Hamilton


Impact of COVID-19 restrictions on diabetes health checks and prescribing for people with type 2 diabetes: a UK-wide cohort study involving 618 161 people in primary care


Authors: M. Carr, A. Wright, L. Leelarathna, H. Thabit, N. Milne, N. Kanumilli, D. Ashcroft, M. Rutter


The Impact of Demographic, Socio-Economic and Geographic Factors on Mortality Risk among People Living with Dementia in England (2002-2016)


Authors: J. Watson, F. Darlington-Pollock, M. Green, C. Giebel, A. Akpan


Impact of influenza vaccination on amoxicillin prescriptions in older adults: A retrospective cohort study using primary care data


Authors: L. Rodgers, A. Streeter, N. Lin, W. Hamilton, W. Henley


The impact of severe mental illness on healthcare use and health outcomes for people with type 2 diabetes


Authors: L. Han, T. Doran, R. Holt, C. Hewitt, R. Jacobs, S. Prady, S. Alderson, D. Shiers, H. Wang, S. Bellass, S. Gilbody, C. Kitchen, J. Lister, J. Taylor, N. Siddiqi


Incidence and prevalence of Juvenile Idiopathic Arthritis in the United Kingdom 2000-2018: results from the Clinical Practice Research Datalink


Authors: R. Costello, J. McDonagh, K. Hyrich, J. Humphreys


Incidence and survival of haemophagocytic lymphohistiocytosis: A population-based cohort study from England


Authors: J. West, T. Card, M. Bishton, P. Lanyon, L. Ban, M. Bythell, L. Elliss-Brookes, J. Manson, V. Nanduri, J. Rankin, R. Tattersall, C. Crooks


Incidence, hospitalization and mortality and their changes over time in people with a first ever diabetic foot ulcer


Authors: J. R\oikjer, N. Werkman, N. Ejskjaer, J. van den Bergh, P. Vestergaard, N. Schaper, M. Jensen, O. Klungel, F. de Vries, J. Nielen, J. Driessen, N. Ejskjaer, J. van den Bergh, P. Vestergaard, N. Schaper, Hasselstr\om Jensen, O. Klungel, F. de Vries, J. Nielen, J. Driessen, F. de Vries


Increased mortality risk in patients with primary and secondary adrenal insufficiency


Authors: K. Ngaosuwan, D. Johnston, I. Godsland, J. Cox, A. Majeed, J. Quint, N. Oliver, S. Robinson


The increasing incidence and prevalence of hypereosinophilic syndrome in the United Kingdom


Authors: G. Requena, J. Logie, D. Gibbons, J. Steinfeld, M. Van Dyke


Incretin-Based Drugs and Risk of Intestinal Obstruction Among Patients with Type 2 Diabetes


Authors: J. Faillie, H. Yin, O. H. Y. Yu, A. Herrero, R. Altwegg, C. Renoux, L. Azoulay


Indirect acute effects of the COVID-19 pandemic on physical and mental health in the UK: a population-based study


Authors: K. Mansfield, R. Mathur, J. Tazare, A. Henderson, A. Mulick, H. Carreira, A. Matthews, P. Bidulka, A. Gayle, H. Forbes, S. Cook, A. Wong, H. Strongman, K. Wing, C. Warren-Gash, S. Cadogan, L. Smeeth, J. Hayes, J. Quint, M. McKee, S. Langan


Inequalities in incident and prevalent multimorbidity in England, 2004\textendash19: a population-based, descriptive study


Authors: A. Head, K. Fleming, C. Kypridemos, P. Schofield, J. Pearson-Stuttard, M. O\textquoterightFlaherty


Infection-related complications after common infection in association with new antibiotic prescribing in primary care: retrospective cohort study using linked electronic health records


Authors: B. van Bodegraven, V. Palin, C. Mistry, M. Sperrin, A. White, W. Welfare, D. Ashcroft, T. van Staa