Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,500 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 6 July 2020) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 3MB, 206 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 2551 results:
Author Title Type [ Year(Desc)]
R. A. Marrie, Wolfson, C., Sturkenboom, M. C., Gout, O., Heinzlef, O., Roullet, E., and Abenhaim, L., Multiple sclerosis and antecedent infections: a case-control study, Neurology, vol. 54, pp. 2307-10, 2000.
T. P. van Staa, Leufkens, H. G., Abenhaim, L., Zhang, B., and Cooper, C., Oral corticosteroids and fracture risk: relationship to daily and cumulative doses, Rheumatology (Oxford), vol. 39, pp. 1383-9, 2000.
A. Ruigomez, Rodriguez, L. A. Garcia, Hasselgren, G., Johansson, S., and Wallander, M. A., Overall mortality among patients surviving an episode of peptic ulcer bleeding, J Epidemiol Community Health, vol. 54, pp. 130-3, 2000.
B. Ineichen, Logie, J., Rowlands, S., and Lawrenson, R., Patterns of prescription of PC4 by general practitioners in England and Wales, Eur J Contracept Reprod Health Care, vol. 5, pp. 241-7, 2000.
C. R. Meier, Napalkov, P. N., Wegmuller, Y., Jefferson, T., and Jick, H., Population-based study on incidence, risk factors, clinical complications and drug utilisation associated with influenza in the United Kingdom, Eur J Clin Microbiol Infect Dis, vol. 19, pp. 834-42, 2000.
M. Frischer, Heatlie, H., Chapman, S., Bashford, J., Norwood, J., and Millson, D., Ratio of inhaled corticosteroid to bronchodilator treatment and asthma hospitalisation, Curr Med Res Opin, vol. 16, pp. 8-13, 2000.
J. B. Soriano, Maier, W. C., Egger, P., Visick, G., Thakrar, B., Sykes, J., and Pride, N. B., Recent trends in physician diagnosed COPD in women and men in the UK, Thorax, vol. 55, pp. 789-94, 2000.
L. A. Garcia Rodriguez and Huerta-Alvarez, C., Reduced incidence of colorectal adenoma among long-term users of nonsteroidal antiinflammatory drugs: a pooled analysis of published studies and a new population-based study, Epidemiology, vol. 11, pp. 376-81, 2000.
S. Rowlands, Devalia, H., Lawrenson, R., Logie, J., and Ineichen, B., Repeated use of hormonal emergency contraception by younger women in the UK, Br J Fam Plann, vol. 26, pp. 138-43, 2000.
I. A. Eland, Alvarez, C. H., Stricker, B. H., and Rodriguez, L. A., The risk of acute pancreatitis associated with acid-suppressing drugs, Br J Clin Pharmacol, vol. 49, pp. 473-8, 2000.
L. Derby and Maier, W. C., Risk of cataract among users of intranasal corticosteroids, J Allergy Clin Immunol, vol. 105, pp. 912-6, 2000.
S. S. Jick, The risk of gastrointestinal bleed, myocardial infarction, and newly diagnosed hypertension in users of meloxicam, diclofenac, naproxen, and piroxicam, Pharmacotherapy, vol. 20, pp. 741-4, 2000.
C. Gasse, Derby, L. E., Vasilakis, C., and Jick, H., Risk of suicide among users of calcium channel blockers: population based, nested case-control study, Bmj, vol. 320, p. 1251, 2000.
H. Jick, Kaye, J. A., Vasilakis-Scaramozza, C., and Jick, S. S., Risk of venous thromboembolism among users of third generation oral contraceptives compared with users of oral contraceptives with levonorgestrel before and after 1995: cohort and case-control analysis, Bmj, vol. 321, pp. 1190-5, 2000.
H. Jick, Zornberg, G. L., Jick, S. S., Seshadri, S., and Drachman, D. A., Statins and the risk of dementia, Lancet, vol. 356, pp. 1627-31, 2000.
R. Lawrenson, Wyndaele, J. J., Vlachonikolis, I., Farmer, C., and Glickman, S., A UK general practice database study of prevalence and mortality of people with neural tube defects, Clin Rehabil, vol. 14, pp. 627-30, 2000.
T. P. van Staa, Abenhaim, L., Cooper, C., Zhang, B., and Leufkens, H. G., The use of a large pharmacoepidemiological database to study exposure to oral corticosteroids and risk of fractures: validation of study population and results, Pharmacoepidemiol Drug Saf, vol. 9, pp. 359-66, 2000.
T. P. van Staa, Leufkens, H. G., and Cooper, C., Use of nonsteroidal anti-inflammatory drugs and risk of fractures, Bone, vol. 27, pp. 563-8, 2000.
T. P. van Staa, Leufkens, H. G., Abenhaim, L., Zhang, B., and Cooper, C., Use of oral corticosteroids and risk of fractures, J Bone Miner Res, vol. 15, pp. 993-1000, 2000.
T. P. van Staa, Leufkens, H. G., Abenhaim, L., Begaud, B., Zhang, B., and Cooper, C., Use of oral corticosteroids in the United Kingdom, Qjm, vol. 93, pp. 105-11, 2000.
R. Lawrenson, Todd, J. C., Leydon, G. M., Williams, T. J., and Farmer, R. D., Validation of the diagnosis of venous thromboembolism in general practice database studies, Br J Clin Pharmacol, vol. 49, pp. 591-6, 2000.
R. Lawrenson and Farmer, R., Venous thromboembolism and combined oral contraceptives: does the type of progestogen make a difference?, Contraception, vol. 62, p. 21S-28S; discussion 37S-38S, 2000.
J. A. Kaye, Myers, M. W., and Jick, H., Acetaminophen and the risk of renal and bladder cancer in the general practice research database, Epidemiology, vol. 12, pp. 690-4, 2001.
R. A. Lawrenson and Logie, J. W., Antibiotic failure in the treatment of urinary tract infections in young women, J Antimicrob Chemother, vol. 48, pp. 895-901, 2001.
S. Hajat, Haines, A., Atkinson, R. W., Bremner, S. A., Anderson, H. R., and Emberlin, J., Association between air pollution and daily consultations with general practitioners for allergic rhinitis in London, United Kingdom, Am J Epidemiol, vol. 153, pp. 704-14, 2001.
L. Smeeth, Hall, A. J., Fombonne, E., Rodrigues, L. C., Huang, X., and Smith, P. G., A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database: design and methodology, BMC Public Health, vol. 1, p. 2, 2001.
M. J. van Bommel, Numans, M. E., de Wit, N. J., and Stalman, W. A., Consultations and referrals for dyspepsia in general practice–a one year database survey, Postgrad Med J, vol. 77, pp. 514-8, 2001.
R. G. Gibbs, Newson, R., Lawrenson, R., Greenhalgh, R. M., and Davies, A. H., Diagnosis and initial management of stroke and transient ischemic attack across UK health regions from 1992 to 1996: experience of a national primary care database, Stroke, vol. 32, pp. 1085-90, 2001.
N. Andrews, Miller, E., Waight, P., Farrington, P., Crowcroft, N., Stowe, J., and Taylor, B., Does oral polio vaccine cause intussusception in infants? Evidence from a sequence of three self-controlled cases series studies in the United Kingdom, Eur J Epidemiol, vol. 17, pp. 701-6, 2001.
S. Hernandez-Diaz and Garcia-Rodriguez, L. A., Epidemiologic assessment of the safety of conventional nonsteroidal anti-inflammatory drugs, Am J Med, vol. 110 Suppl 3A, p. 20s-7s, 2001.
T. P. van Staa, Dennison, E. M., Leufkens, H. G., and Cooper, C., Epidemiology of fractures in England and Wales, Bone, vol. 29, pp. 517-22, 2001.
A. McGuire, Irwin, D. E., Fenn, P., Gray, A., Anderson, P., Lovering, A., and MacGowan, A., The excess cost of acute exacerbations of chronic bronchitis in patients aged 45 and older in England and Wales, Value Health, vol. 4, pp. 370-5, 2001.
A. Ruigomez, Johansson, S., Wallander, M. A., and Rodriguez, L. A. Garcia, Gender and drug treatment as determinants of mortality in a cohort of heart failure patients, Eur J Epidemiol, vol. 17, pp. 329-35, 2001.
S. Johansson, Wallander, M. A., Ruigomez, A., and Rodriguez, L. A. Garcia, Incidence of newly diagnosed heart failure in UK general practice, Eur J Heart Fail, vol. 3, pp. 225-31, 2001.
C. Huerta and Rodriguez, L. A., Incidence of ocular melanoma in the general population and in glaucoma patients, J Epidemiol Community Health, vol. 55, pp. 338-9, 2001.
K. Moser, Inequalities in treated heart disease and mental illness in England and Wales, 1994-1998, Br J Gen Pract, vol. 51, pp. 438-44, 2001.
L. M. Higuchi, Joffe, S., Neufeld, E. J., Weisdorf, S., Rosh, J., Murch, S., Devenyi, A., Thompson, J. F., Lewis, J. D., and Bousvaros, A., Inflammatory bowel disease associated with immune thrombocytopenic purpura in children, J Pediatr Gastroenterol Nutr, vol. 33, pp. 582-7, 2001.
J. D. Lewis, Bilker, W. B., Brensinger, C., Deren, J. J., Vaughn, D. J., and Strom, B. L., Inflammatory bowel disease is not associated with an increased risk of lymphoma, Gastroenterology, vol. 121, pp. 1080-7, 2001.
D. Gaist, Rodriguez, L. A., Huerta, C., Hallas, J., and Sindrup, S. H., Lipid-lowering drugs and risk of myopathy: a population-based follow-up study, Epidemiology, vol. 12, pp. 565-9, 2001.
H. Jick, Vasilakis-Scaramozza, C., and Jick, S. S., Live attenuated polio vaccine and the risk of intussusception, Br J Clin Pharmacol, vol. 52, pp. 451-3, 2001.
J. W. Logie, Clifford, G. M., Farmer, R. D., and Meesen, B. P., Lower urinary tract symptoms suggestive of benign prostatic obstruction–Triumph: the role of general practice databases, Eur Urol, vol. 39 Suppl 3, pp. 42-7, 2001.
C. R. Chapple, Lower urinary tract symptoms suggestive of benign prostatic obstruction–Triumph: design and implementation, Eur Urol, vol. 39 Suppl 3, pp. 31-6, 2001.
J. A. Kaye, M. Melero-Montes, delMar, and Jick, H., Mumps, measles, and rubella vaccine and the incidence of autism recorded by general practitioners: a time trend analysis, Bmj, vol. 322, pp. 460-3, 2001.
S. Rowlands, Devalia, H., Smith, C., Hubbard, R., and Dean, A., Otitis externa in UK general practice: a survey using the UK General Practice Research Database, Br J Gen Pract, vol. 51, pp. 533-8, 2001.
C. R. Gale, Edington, J., Coles, S. J., and Martyn, C. N., Patterns of prescribing of nutritional supplements in the United Kingdom, Clin Nutr, vol. 20, pp. 333-7, 2001.
S. Seshadri, Zornberg, G. L., Derby, L. E., Myers, M. W., Jick, H., and Drachman, D. A., Postmenopausal estrogen replacement therapy and the risk of Alzheimer disease, Arch Neurol, vol. 58, pp. 435-40, 2001.
S. Rowlands, Devalia, H., and Lawrenson, R., Preferential prescribing of type of combined oral contraceptive pill by general practitioners to teenagers with acne, Eur J Contracept Reprod Health Care, vol. 6, pp. 9-13, 2001.
C. Ellis, Gnani, S., and Majeed, A., Prevalence and management of heart failure in general practice in England and Wales, 1994-98, Health Stat Q., pp. 17-24, 2001.
A. MFG, Prevalence of comorbid mental illness and drug use recorded in general practice: preliminary findings from the general practice research database, Drugs: education, prevention and policy, vol. 8, pp. 275-80, 2001.
R. Ryan and Majeed, A., Prevalence of ischaemic heart disease and its management with statins and aspirin in general practice in England and Wales, 1994 and 1998, Health Statistics Quartely, vol. 12, pp. 34-39, 2001.
[Page last reviewed 6 July 2020]