Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,500 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 5 August 2020) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 3MB, 207 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 2566 results:
Author [ Title(Desc)] Type Year
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 
E. P. Vamos, Pape, U. J., Bottle, A., Hamilton, F. L., Curcin, V., Ng, A., Molokhia, M., Car, J., Majeed, A., and Millett, C., Association of practice size and pay-for-performance incentives with the quality of diabetes management in primary care, Cmaj, vol. 183, pp. E809-16, 2011.
A. Root, Brown, J. P., Forbes, H. J., Bhaskaran, K., Hayes, J., Smeeth, L., and Douglas, I. J., Association of Relative Age in the School Year With Diagnosis of Intellectual Disability, Attention-Deficit/Hyperactivity Disorder, and Depression, JAMA Pediatr, 2019.
C. Renoux, Vahey, S., Dell'Aniello, S., and Boivin, J. F., Association of Selective Serotonin Reuptake Inhibitors With the Risk for Spontaneous Intracranial Hemorrhage, JAMA Neurol, vol. 74, pp. 173-180, 2017.
S. K. Paul, Klein, K., Majeed, A., and Khunti, K., Association of smoking and concomitant metformin use with cardiovascular events and mortality in people newly diagnosed with type 2 diabetes, J Diabetes, vol. 8, pp. 354-62, 2016.
A. Alonso, Logroscino, G., Jick, S. S., and Hernan, M. A., Association of smoking with amyotrophic lateral sclerosis risk and survival in men and women: a prospective study, BMC Neurol, vol. 10, p. 6, 2010.
E. P. Vamos, Harris, M., Millett, C., Pape, U. J., Khunti, K., Curcin, V., Molokhia, M., and Majeed, A., Association of systolic and diastolic blood pressure and all cause mortality in people with newly diagnosed type 2 diabetes: retrospective cohort study, Bmj, vol. 345, p. e5567, 2012.
M. T. Redaniel, Gardner, M. P., Martin, R. M., and Jeffreys, M., The association of vitamin D supplementation with the risk of cancer in postmenopausal women, Cancer Causes Control, vol. 25, pp. 267-71, 2014.
E. Kontopantelis, Springate, D. A., Ashcroft, D. M., Valderas, J. M., van der Veer, S. N., Reeves, D., Guthrie, B., and Doran, T., Associations between exemption and survival outcomes in the UK's primary care pay-for-performance programme: a retrospective cohort study, BMJ Qual Saf, vol. 25, pp. 657-70, 2016.
H. Fan, Gilbert, R., O'Callaghan, F., and Li, L., Associations between macrolide antibiotics prescribing during pregnancy and adverse child outcomes in the UK: population based cohort study, Bmj, vol. 368, p. m331, 2020.
M. Pujades-Rodriguez, Duyx, B., Thomas, S. L., Stogiannis, D., Smeeth, L., and Hemingway, H., Associations between polymyalgia rheumatica and giant cell arteritis and 12 cardiovascular diseases, Heart, vol. 102, pp. 383-9, 2016.
P. G. Kehoe, Davies, N. M., Martin, R. M., and Ben-Shlomo, Y., Associations of angiotensin targeting antihypertensive drugs with mortality and hospitalization in primary care patients with dementia, J Alzheimers Dis, vol. 33, pp. 999-1008, 2013.
B. Yang, Hagberg, K. W., Chen, J., Sahasrabuddhe, V. V., Graubard, B. I., Jick, S., and McGlynn, K. A., Associations of antibiotic use with risk of primary liver cancer in the Clinical Practice Research Datalink, Br J Cancer, vol. 115, pp. 85-9, 2016.
N. M. Davies, Kehoe, P. G., Ben-Shlomo, Y., and Martin, R. M., Associations of anti-hypertensive treatments with Alzheimer's disease, vascular dementia, and other dementias, J Alzheimers Dis, vol. 26, pp. 699-708, 2011.
S. Hajat and Haines, A., Associations of cold temperatures with GP consultations for respiratory and cardiovascular disease amongst the elderly in London, Int J Epidemiol, vol. 31, pp. 825-30, 2002.
B. Yang, Petrick, J. L., Chen, J., Hagberg, K. W., Sahasrabuddhe, V. V., Graubard, B. I., Jick, S., and McGlynn, K. A., Associations of NSAID and paracetamol use with risk of primary liver cancer in the Clinical Practice Research Datalink, Cancer Epidemiol, vol. 43, pp. 105-11, 2016.
M. T. Redaniel, Jeffreys, M., May, M. T., Ben-Shlomo, Y., and Martin, R. M., Associations of type 2 diabetes and diabetes treatment with breast cancer risk and mortality: a population-based cohort study among British women, Cancer Causes Control, vol. 23, pp. 1785-95, 2012.
S. R. Pye, Sheppard, T., Joseph, R. M., Lunt, M., Girard, N., Haas, J. S., Bates, D. W., Buckeridge, D. L., van Staa, T. P., Tamblyn, R., and Dixon, W. G., Assumptions made when preparing drug exposure data for analysis have an impact on results: An unreported step in pharmacoepidemiology studies, Pharmacoepidemiol Drug Saf, vol. 27, pp. 781-788, 2018.
C. Vasilakis-Scaramozza, Aschengrau, A., Cabral, H. J., and Jick, S. S., Asthma drugs and the risk of congenital anomalies, Pharmacotherapy, vol. 33, pp. 363-8, 2013.
R. A. Charlton, Hutchison, A., Davis, K. J., and de Vries, C. S., Asthma management in pregnancy, PLoS One, vol. 8, p. e60247, 2013.
R. A. Charlton, Pierini, A., Klungsoyr, K., Neville, A. J., Jordan, S., van den Berg, L. T. de Jong, Thayer, D., Bos, H. J., Puccini, A., Hansen, A. V., Gini, R., Engeland, A., Andersen, A. M. Nybo, Dolk, H., and Garne, E., Asthma medication prescribing before, during and after pregnancy: a study in seven European regions, BMJ Open, vol. 6, p. e009237, 2016.
C. I. Bloom, Cabrera, C., Arnetorp, S., Coulton, K., Nan, C., van der Valk, R. J. P., and Quint, J. K., Asthma-Related Health Outcomes Associated with Short-Acting β(2)-Agonist Inhaler Use: An Observational UK Study as Part of the SABINA Global Program, Adv Ther, 2020.
K. E. Lowe, Mansfield, K. E., Delmestri, A., Smeeth, L., Roberts, A., Abuabara, K., Prieto-Alhambra, D., and Langan, S. M., Atopic eczema and fracture risk in adults: A population-based cohort study, J Allergy Clin Immunol, 2019.
Y. Schonmann, Mansfield, K. E., Hayes, J. F., Abuabara, K., Roberts, A., Smeeth, L., and Langan, S. M., Atopic eczema in adulthood and risk of depression and anxiety: a population-based cohort study, J Allergy Clin Immunol Pract, 2019.
A. C. Scowcroft and Cowie, M. R., Atrial fibrillation: improvement in identification and stroke preventive therapy - data from the UK Clinical Practice Research Datalink, 2000-2012, Int J Cardiol, vol. 171, pp. 169-73, 2014.
S. McCarthy, Asherson, P., Coghill, D., Hollis, C., Murray, M., Potts, L., Sayal, K., de Soysa, R., Taylor, E., Williams, T., and Wong, I. C., Attention-deficit hyperactivity disorder: treatment discontinuation in adolescents and young adults, Br J Psychiatry, vol. 194, pp. 273-7, 2009.
V. Prasad, West, J., Kendrick, D., and Sayal, K., Attention-deficit/hyperactivity disorder: variation by socioeconomic deprivation, Arch Dis Child, 2018.
N. N. Mehta, Yu, Y., Pinnelas, R., Krishnamoorthy, P., Shin, D. B., Troxel, A. B., and Gelfand, J. M., Attributable risk estimate of severe psoriasis on major cardiovascular events, Am J Med, vol. 124, pp. 775.e1-6, 2011.
L. L. Lipscombe, Austin, P. C., Alessi-Severini, S., Blackburn, D. F., Blais, L., Bresee, L., Filion, K. B., Kawasumi, Y., Kurdyak, P., Platt, R. W., Tamim, H., and Paterson, J. M., Atypical antipsychotics and hyperglycemic emergencies: multicentre, retrospective cohort study of administrative data, Schizophr Res, vol. 154, pp. 54-60, 2014.
H. Jick and Kaye, J. A., Autism and DPT vaccination in the United Kingdom, N Engl J Med, vol. 350, pp. 2722-3, 2004.
A. Lawson, West, J., Aithal, G. P., and Logan, R. F., Autoimmune cholestatic liver disease in people with coeliac disease: a population-based study of their association, Aliment Pharmacol Ther, vol. 21, pp. 401-5, 2005.
T. M. Anssar, Leitzmann, M. F., Linker, R. A., Meier, C., Becker, C., Jick, S., Sahm, K., Platten, M., Hau, P., and Seliger, C., Autoimmune diseases and immunosuppressive therapy in relation to the risk of glioma, Cancer Med, 2019.
K. W. Littink, Stappers, P. T. Y., Riemslag, F. C. C., Talsma, H. E., van Genderen, M. M., Cremers, F. P. M., Collin, R. W. J., and van den Born, L. I., Autosomal Recessive NRL Mutations in Patients with Enhanced S-Cone Syndrome, Genes (Basel), vol. 9, 2018.
B. A. Dickerman, Garcia-Albeniz, X., Logan, R. W., Denaxas, S., and Hernan, M. A., Avoidable flaws in observational analyses: an application to statins and cancer, Nat Med, 2019.
I. J. Douglas, Bhaskaran, K., Batterham, R. L., and Smeeth, L., Bariatric Surgery in the United Kingdom: A Cohort Study of Weight Loss and Clinical Outcomes in Routine Clinical Care, PLoS Med, vol. 12, p. e1001925, 2015.
K. van Brunt, Curtis, B., Ivanyi, T., Balogh, E., Chalkiadaki, C., MacLachlan, S., Neasham, D., and Raluy-Callado, M., Basal-bolus Therapy in Patients with Type 2 Diabetes Mellitus in the UK: Patient Characteristics, Treatment Patterns and the Effect of Switching to Premixed Insulin, Diabetes Ther, vol. 7, pp. 793-807, 2016.
S. F. Lanes, Rodrigeuz, L. A., and Hwangg, E., Baseline risk of gastrointestinal disorders among new users of meloxicam, ibuprofen, diclofenac, naproxen and indomethacin, Pharmacoepidemiol Drug Saf, vol. 9, pp. 113-7, 2000.
J. Stowe, Andrews, N., Wise, L., and Miller, E., Bell's palsy and parenteral inactivated influenza vaccine, Hum Vaccin, vol. 2, pp. 110-2, 2006.
J. P. Sheppard, Stevens, S., Stevens, R., Martin, U., Mant, J., Hobbs, F. D. R., and McManus, R. J., Benefits and Harms of Antihypertensive Treatment in Low-Risk Patients With Mild Hypertension, JAMA Intern Med, vol. 178, pp. 1626-1634, 2018.
D. B. Wolfson, Best, A. F., Addona, V., Wolfson, J., and Gadalla, S. M., Benefits of combining prevalent and incident cohorts: An application to myotonic dystrophy, Stat Methods Med Res, p. 962280218804275, 2018.
R. Alsaggaf, St George, D. M. M., Zhan, M., Pfeiffer, R. M., Wang, Y., Anderson, L. A., Liu, Z., Koshiol, J., Bauer, A. J., Wagner, K. R., Greene, M. H., Amr, S., and Gadalla, S. M., Benign tumors in myotonic dystrophy type I target disease-related cancer sites, Ann Clin Transl Neurol, vol. 6, pp. 1510-1518, 2019.
P. Imfeld, Bodmer, M., Jick, S. S., and Meier, C. R., Benzodiazepine Use and Risk of Developing Alzheimer's Disease or Vascular Dementia: A Case-Control Analysis, Drug Saf, vol. 38, pp. 909-19, 2015.
A. Palmaro, Dupouy, J., and Lapeyre-Mestre, M., Benzodiazepines and risk of death: Results from two large cohort studies in France and UK, Eur Neuropsychopharmacol, vol. 25, pp. 1566-77, 2015.
F. Giorgianni, Ernst, P., Dell'Aniello, S., Suissa, S., and Renoux, C., Beta 2 agonists and the incidence of Parkinson's disease, Am J Epidemiol, 2020.
C. McCourt, Coleman, H. G., Murray, L. J., Cantwell, M. M., Dolan, O., Powe, D. G., and Cardwell, C. R., Beta-blocker usage after malignant melanoma diagnosis and survival: a population-based nested case-control study, Br J Dermatol, vol. 170, pp. 930-8, 2014.
C. R. Cardwell, Coleman, H. G., Murray, L. J., Entschladen, F., and Powe, D. G., Beta-blocker usage and breast cancer survival: a nested case-control study within a UK clinical practice research datalink cohort, Int J Epidemiol, vol. 42, pp. 1852-61, 2013.
B. M. Hicks, Murray, L. J., Powe, D. G., Hughes, C. M., and Cardwell, C. R., beta-Blocker usage and colorectal cancer mortality: a nested case-control study in the UK Clinical Practice Research Datalink cohort, Ann Oncol, vol. 24, pp. 3100-6, 2013.
C. Renoux, Dell'Aniello, S., Brenner, B., and Suissa, S., Bias from depletion of susceptibles: the example of hormone replacement therapy and the risk of venous thromboembolism, Pharmacoepidemiol Drug Saf, vol. 26, pp. 554-560, 2017.
S. J. Sinnott, Mansfield, K. E., Schmidt, M., Bhaskaran, K., Smeeth, L., Nitsch, D., and Tomlinson, L. A., Biochemical monitoring after initiation of aldosterone antagonist therapy in users of renin-angiotensin system blockers: a UK primary care cohort study, BMJ Open, vol. 7, p. e018153, 2017.
J. Spoendlin, Meier, C., Jick, S. S., and Meier, C. R., Bisphosphonate therapy start may transiently increase the risk of tendon rupture in patients with glucocorticoid co-medication: a population-based observational study, Pharmacoepidemiol Drug Saf, vol. 25, pp. 1116-1123, 2016.
W. G. Dixon and Solomon, D. H., Bisphosphonates and esophageal cancer–a pathway through the confusion, Nat Rev Rheumatol, vol. 7, pp. 369-72, 2011.
[Page last reviewed 5 August 2020]