Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,500 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 5 May 2020) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 3MB, 203 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 2509 results:
Author Title Type [ Year(Desc)]
R. B. Hubbard, Smith, C. J., Smeeth, L., Harrison, T. W., and Tattersfield, A. E., Inhaled corticosteroids and hip fracture: a population-based case-control study, Am J Respir Crit Care Med, vol. 166, pp. 1563-6, 2002.
B. D. Bradbury and Jick, S. S., Itraconazole and fluconazole and certain rare, serious adverse events, Pharmacotherapy, vol. 22, pp. 697-700, 2002.
M. C. Sheppard, Holder, R., and Franklyn, J. A., Levothyroxine treatment and occurrence of fracture of the hip, Arch Intern Med, vol. 162, pp. 338-43, 2002.
D. J. Watson, Rhodes, T., Cai, B., and Guess, H. A., Lower risk of thromboembolic cardiovascular events with naproxen among patients with rheumatoid arthritis, Arch Intern Med, vol. 162, pp. 1105-10, 2002.
T. M. McKeever, Lewis, S. A., Smith, C., and Hubbard, R., Mode of delivery and risk of developing allergic disease, J Allergy Clin Immunol, vol. 109, pp. 800-2, 2002.
J. Y. Kang, Tinto, A., Higham, J., and Majeed, A., Peptic ulceration in general practice in England and Wales 1994-98: period prevalence and drug management, Aliment Pharmacol Ther, vol. 16, pp. 1067-74, 2002.
R. M. Martin, Hemingway, H., Gunnell, D., Karsch, K. R., Baumbach, A., and Frankel, S., Population need for coronary revascularisation: are national targets for England credible?, Heart, vol. 88, pp. 627-33, 2002.
K. M. Wyatt, Dimmock, P. W., Frischer, M., Jones, P. W., and O'Brien, S. P., Prescribing patterns in premenstrual syndrome, BMC Womens Health, vol. 2, p. 4, 2002.
A. Newnham, Ryan, R., Khunti, K., and Majeed, A., Prevalence of diagnosed diabetes mellitus in general practice in England and Wales, 1994 to 1998, Health Stat Q, pp. 5-13, 2002.
R. Ryan and Majeed, A., Prevalence of treated hypertension in general practice in England and Wales, 1994 to 1998., Health Stat Q, pp. 14-8, 2002.
C. Black, Kaye, J. A., and Jick, H., Relation of childhood gastrointestinal disorders to autism: nested case-control study using data from the UK General Practice Research Database, Bmj, vol. 325, pp. 419-21, 2002.
S. F. Lanes, Rodriguez, L. A. Garcia, and Huerta, C., Respiratory medications and risk of asthma death, Thorax, vol. 57, pp. 683-6, 2002.
C. Huerta, Zhao, S. Z., and Rodriguez, L. A. Garcia, Risk of acute liver injury in patients with diabetes, Pharmacotherapy, vol. 22, pp. 1091-6, 2002.
C. Huerta and Rodriguez, L. A. Garcia, Risk of clinical blood dyscrasia in a cohort of antibiotic users, Pharmacotherapy, vol. 22, pp. 630-6, 2002.
C. Huerta, Rodriguez, L. A. Garcia, Wallander, M. A., and Johansson, S., Risk of irritable bowel syndrome among asthma patients, Pharmacoepidemiol Drug Saf, vol. 11, pp. 31-5, 2002.
A. Ruigomez, Johansson, S., Wallander, M. A., and Rodriguez, L. A. Garcia, Risk of mortality in a cohort of patients newly diagnosed with chronic atrial fibrillation, BMC Cardiovasc Disord, vol. 2, p. 5, 2002.
J. Castellsague, Garcia-Rodriguez, L. A., Duque, A., and Perez, S., Risk of serious skin disorders among users of oral antifungals: a population-based study, BMC Dermatol, vol. 2, p. 14, 2002.
J. A. Kaye, Meier, C. R., Walker, A. M., and Jick, H., Statin use, hyperlipidaemia, and the risk of breast cancer, Br J Cancer, vol. 86, pp. 1436-9, 2002.
C. C. Yang, Jick, S. S., and Jick, H., Statins and the risk of idiopathic venous thromboembolism, Br J Clin Pharmacol, vol. 53, pp. 101-5, 2002.
J. B. Soriano, Vestbo, J., Pride, N. B., Kiri, V., Maden, C., and Maier, W. C., Survival in COPD patients after regular use of fluticasone propionate and salmeterol in general practice, Eur Respir J, vol. 20, pp. 819-25, 2002.
S. Johansson, Wallander, M. A., Ruigomez, A., and Garcia, R., Treatment patterns among newly diagnosed heart failure patients in general practice, Eur J Clin Pharmacol, vol. 57, pp. 813-7, 2002.
K. Bailey, Ellis, C., and Majeed, A., Trends in the treatment of osteoporosis and types of drug treatments prescribed in general practice in England and Wales, 1994 to 1998, Health Stat Q, pp. 5-13, 2002.
R. G. Schlienger, Jick, H., and Meier, C. R., Use of nonsteroidal anti-inflammatory drugs and the risk of first-time acute myocardial infarction, Br J Clin Pharmacol, vol. 54, pp. 327-32, 2002.
T. P. van Staa, Leufkens, H. G., and Cooper, C., Utility of medical and drug history in fracture risk prediction among men and women, Bone, vol. 31, pp. 508-14, 2002.
J. D. Lewis, Brensinger, C., Bilker, W. B., and Strom, B. L., Validity and completeness of the General Practice Research Database for studies of inflammatory bowel disease, Pharmacoepidemiol Drug Saf, vol. 11, pp. 211-8, 2002.
D. J. Margolis, Bilker, W., Santanna, J., and Baumgarten, M., Venous leg ulcer: incidence and prevalence in the elderly, J Am Acad Dermatol, vol. 46, pp. 381-6, 2002.
B. L. Strom, Schinnar, R., Apter, A. J., Margolis, D. J., Lautenbach, E., Hennessy, S., Bilker, W. B., and Pettitt, D., Absence of cross-reactivity between sulfonamide antibiotics and sulfonamide nonantibiotics, N Engl J Med, vol. 349, pp. 1628-35, 2003.
D. J. Watson, Rhodes, T., and Guess, H. A., All-cause mortality and vascular events among patients with rheumatoid arthritis, osteoarthritis, or no arthritis in the UK General Practice Research Database, J Rheumatol, vol. 30, pp. 1196-202, 2003.
W. A. Blumentals, Brown, R. R., and Gomez-Caminero, A., Antihypertensive treatment and erectile dysfunction in a cohort of type II diabetes patients, Int J Impot Res, vol. 15, pp. 314-7, 2003.
L. Smeeth, Hubbard, R., and Fletcher, A. E., Cataract and the use of statins: a case-control study, Qjm, vol. 96, pp. 337-43, 2003.
J. A. Kaye, Bradbury, B. D., and Jick, H., Changes in antipsychotic drug prescribing by general practitioners in the United Kingdom from 1991 to 2000: a population-based observational study, Br J Clin Pharmacol, vol. 56, pp. 569-75, 2003.
T. M. MacDonald, Morant, S. V., Goldstein, J. L., Burke, T. A., and Pettitt, D., Channelling bias and the incidence of gastrointestinal haemorrhage in users of meloxicam, coxibs, and older, non-specific non-steroidal anti-inflammatory drugs, Gut, vol. 52, pp. 1265-70, 2003.
T. P. van Staa, Cooper, C., Leufkens, H. G., and Bishop, N., Children and the risk of fractures caused by oral corticosteroids, J Bone Miner Res, vol. 18, pp. 913-8, 2003.
J. Hoare, Comparison of area-based inequality measures and disease morbidity in England, 1994–1998., Health Stat Q, vol. 18, pp. 18-24, 2003.
C. Deschaseaux-Voinet, Lafuma, A., and Berdeaux, G., Cost and effectiveness of brinzolamide versus dorzolamide in current practice: an analysis based on the UK-GPRD database, J Med Econ, vol. 6, pp. 69-78, 2003.
G. T. McInnes, The differences between ACE inhibitor-treated and calcium channel blocker-treated hypertensive patients, J Clin Hypertens (Greenwich), vol. 5, pp. 337-44, 2003.
H. E. Seaman, de Vries, C. S., and Farmer, R. D., Differences in the use of combined oral contraceptives amongst women with and without acne, Hum Reprod, vol. 18, pp. 515-21, 2003.
C. C. Yang, Jick, S. S., and Testa, M. A., Discontinuation and switching of therapy after initiation of lipid-lowering drugs: the effects of comorbidities and patient characteristics, Br J Clin Pharmacol, vol. 56, pp. 84-91, 2003.
L. J. Tata, West, J., Harrison, T., Farrington, P., Smith, C., and Hubbard, R., Does influenza vaccination increase consultations, corticosteroid prescriptions, or exacerbations in subjects with asthma or chronic obstructive pulmonary disease?, Thorax, vol. 58, pp. 835-9, 2003.
S. A. Bremner, Carey, I. M., DeWilde, S., Richards, N., Maier, W. C., Hilton, S. R., Strachan, D. P., and Cook, D. G., Early-life exposure to antibacterials and the subsequent development of hayfever in childhood in the UK: case-control studies using the General Practice Research Database and the Doctors' Independent Network, Clin Exp Allergy, vol. 33, pp. 1518-25, 2003.
H. Jick and Kaye, J. A., Epidemiology and possible causes of autism, Pharmacotherapy, vol. 23, pp. 1524-30, 2003.
R. Hubbard, Farrington, P., Smith, C., Smeeth, L., and Tattersfield, A., Exposure to tricyclic and selective serotonin reuptake inhibitor antidepressants and the risk of hip fracture, Am J Epidemiol, vol. 158, pp. 77-84, 2003.
J. West, Logan, R. F., Card, T. R., Smith, C., and Hubbard, R., Fracture risk in people with celiac disease: a population-based cohort study, Gastroenterology, vol. 125, pp. 429-36, 2003.
S. Smith, Smith, G., Heatlie, H., Bashford, J., Ashcroft, D., and Millson, D., Head lice diagnosed in general practice in the West Midlands between 1993 and 2000: a survey using the General Practice Research Database, Commun Dis Public Health, vol. 6, pp. 139-43, 2003.
A. Ruigomez, Rodriguez, L. A. Garcia, Johansson, S., and Wallander, M. A., Is hormone replacement therapy associated with an increased risk of irritable bowel syndrome?, Maturitas, vol. 44, pp. 133-40, 2003.
I. M. Carey, Cook, D. G., De Wilde, S., Bremner, S. A., Richards, N., Caine, S., Strachan, D. P., and Hilton, S. R., Implications of the problem orientated medical record (POMR) for research using electronic GP databases: a comparison of the Doctors Independent Network Database (DIN) and the General Practice Research Database (GPRD), BMC Fam Pract, vol. 4, p. 14, 2003.
J. Hollowell, Ruigomez, A., Johansson, S., Wallander, M. A., and Garcia-Rodriguez, L. A., The incidence of bleeding complications associated with warfarin treatment in general practice in the United Kingdom, Br J Gen Pract, vol. 53, pp. 312-4, 2003.
J. A. Kaye and Jick, H., Incidence of erectile dysfunction and characteristics of patients before and after the introduction of sildenafil in the United Kingdom: cross sectional study with comparison patients, Bmj, vol. 326, pp. 424-5, 2003.
S. Rowlands and Hannaford, P., The incidence of sterilisation in the UK, Bjog, vol. 110, pp. 819-24, 2003.
P. D. van der Linden, Sturkenboom, M. C., Herings, R. M., Leufkens, H. M., Rowlands, S., and Stricker, B. H., Increased risk of achilles tendon rupture with quinolone antibacterial use, especially in elderly patients taking oral corticosteroids, Arch Intern Med, vol. 163, pp. 1801-7, 2003.
[Page last reviewed 5 May 2020]