Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 November 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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C. R. Chapple, Lower urinary tract symptoms suggestive of benign prostatic obstruction–Triumph: design and implementation, Eur Urol, vol. 39 Suppl 3, pp. 31-6, 2001.
C. R. Chapple, Nazir, J., Hakimi, Z., Bowditch, S., Fatoye, F., Guelfucci, F., Khemiri, A., Siddiqui, E., and Wagg, A., Persistence and Adherence with Mirabegron versus Antimuscarinic Agents in Patients with Overactive Bladder: A Retrospective Observational Study in UK Clinical Practice, Eur Urol, vol. 72, pp. 389-399, 2017.
R. A. Charlton, McGrogan, A., Snowball, J., Yates, L. M., Wood, A., Clayton-Smith, J., Smithson, W. H., Richardson, J. L., McHugh, N., Thomas, S. H., Baker, G. A., and Bromley, R., Sensitivity of the UK Clinical Practice Research Datalink to Detect Neurodevelopmental Effects of Medicine Exposure in Utero: Comparative Analysis of an Antiepileptic Drug-Exposed Cohort, Drug Saf, vol. 40, pp. 387-397, 2017.
R. A. Charlton, Pierini, A., Klungsoyr, K., Neville, A. J., Jordan, S., van den Berg, L. T. de Jong, Thayer, D., Bos, H. J., Puccini, A., Hansen, A. V., Gini, R., Engeland, A., Andersen, A. M. Nybo, Dolk, H., and Garne, E., Asthma medication prescribing before, during and after pregnancy: a study in seven European regions, BMJ Open, vol. 6, p. e009237, 2016.
R. Charlton, Garne, E., Wang, H., Klungsoyr, K., Jordan, S., Neville, A., Pierini, A., Hansen, A., Engeland, A., Gini, R., Thayer, D., Bos, J., Puccini, A., Andersen, A. M. Nybo, Dolk, H., and L. van den Berg, deJong-, Antiepileptic drug prescribing before, during and after pregnancy: a study in seven European regions, Pharmacoepidemiol Drug Saf, vol. 24, pp. 1144-54, 2015.
R. A. Charlton, Snowball, J. M., Nightingale, A. L., and Davis, K. J., Safety of Fluticasone Propionate Prescribed for Asthma During Pregnancy: A UK Population-Based Cohort Study, J Allergy Clin Immunol Pract, vol. 3, pp. 772-9.e3, 2015.
J. Charlton, Ravindrarajah, R., Hamada, S., Jackson, S. H., and Gulliford, M. C., Trajectory of Total Cholesterol in the Last Years of Life Over Age 80 Years: Cohort Study of 99,758 Participants, J Gerontol A Biol Sci Med Sci, vol. 73, pp. 1083-1089, 2018.
R. Charlton, Green, A., Shaddick, G., Snowball, J., Nightingale, A., Tillett, W., Smith, C. H., and McHugh, N., Risk of uveitis and inflammatory bowel disease in people with psoriatic arthritis: a population-based cohort study, Ann Rheum Dis, vol. 77, pp. 277-280, 2018.
R. Charlton, Green, A., Shaddick, G., Snowball, J., Nightingale, A., Tillett, W., Smith, C., and McHugh, N., Risk of type 2 diabetes and cardiovascular disease in an incident cohort of people with psoriatic arthritis: a population-based cohort study, Rheumatology (Oxford), 2018.
R. Charlton, Snowball, J., Sammon, C., and de Vries, C., The Clinical Practice Research Datalink for drug safety in pregnancy research: an overview, Therapie, vol. 69, pp. 83-9, 2014.
J. Charlton, Rudisill, C., Bhattarai, N., and Gulliford, M., Impact of deprivation on occurrence, outcomes and health care costs of people with multiple morbidity, J Health Serv Res Policy, vol. 18, pp. 215-23, 2013.
R. A. Charlton, Hutchison, A., Davis, K. J., and de Vries, C. S., Asthma management in pregnancy, PLoS One, vol. 8, p. e60247, 2013.
R. A. Charlton, Snowball, J. M., Bloomfield, K., and de Vries, C. S., Colorectal cancer risk reduction following macrogol exposure: a cohort and nested case control study in the UK, PLoS One, vol. 8, p. e83203, 2013.
R. Charlton, Snowball, J., Bloomfield, K., and de Vries, C., Colorectal cancer incidence on the General Practice Research Database, Pharmacoepidemiol Drug Saf, vol. 21, pp. 775-783, 2012.
R. A. Charlton, Weil, J. G., Cunnington, M. C., and de Vries, C. S., Identifying major congenital malformations in the UK General Practice Research Database (GPRD): a study reporting on the sensitivity and added value of photocopied medical records and free text in the GPRD, Drug Saf, vol. 33, pp. 741-50, 2010.
R. A. Charlton, Weil, J. G., Cunnington, M. C., Ray, S., and de Vries, C. S., Comparing the General Practice Research Database and the UK Epilepsy and Pregnancy Register as tools for postmarketing teratogen surveillance: anticonvulsants and the risk of major congenital malformations, Drug Saf, vol. 34, pp. 157-71, 2011.
J. Charlton, Latinovic, R., and Gulliford, M. C., Explaining the decline in early mortality in men and women with type 2 diabetes: a population-based cohort study, Diabetes Care, vol. 31, pp. 1761-6, 2008.
R. A. Charlton, Cunnington, M. C., de Vries, C. S., and Weil, J. G., Data resources for investigating drug exposure during pregnancy and associated outcomes: the General Practice Research Database (GPRD) as an alternative to pregnancy registries, Drug Saf, vol. 31, pp. 39-51, 2008.
Z. Chaudhry, Mannan, F., Gibson-White, A., Syed, U., Ahmed, S., Kousoulis, A., and Majeed, A., Outputs and Growth of Primary Care Databases in the United Kingdom: Bibliometric Analysis, J Innov Health Inform, vol. 24, p. 942, 2017.
S. Cheeta, Drummond, C., Oyefeso, A., Phillips, T., Deluca, P., Perryman, K., and Coulton, S., Low identification of alcohol use disorders in general practice in England, Addiction, vol. 103, pp. 766-73, 2008.
Y. C. Chen, Wu, J. C., Haschler, I., Majeed, A., Chen, T. J., and Wetter, T., Academic impact of a public electronic health database: bibliometric analysis of studies using the general practice research database, PLoS One, vol. 6, p. e21404, 2011.
L. Chen, Reed, C., Happich, M., Nyhuis, A., and Lenox-Smith, A., Health care resource utilisation in primary care prior to and after a diagnosis of Alzheimer's disease: a retrospective, matched case-control study in the United Kingdom, BMC Geriatr, vol. 14, p. 76, 2014.
T. C. Chen, Chen, L. C., and Knaggs, R. D., A 15-year overview of increasing tramadol utilisation and associated mortality and the impact of tramadol classification in the United Kingdom, Pharmacoepidemiol Drug Saf, vol. 27, pp. 487-494, 2018.
A. Cherskov, Pohl, A., Allison, C., Zhang, H., Payne, R. A., and Baron-Cohen, S., Polycystic ovary syndrome and autism: A test of the prenatal sex steroid theory, Transl Psychiatry, vol. 8, p. 136, 2018.
V. Chhaya, Saxena, S., Cecil, E., Subramanian, V., Curcin, V., Majeed, A., and Pollok, R. C., Impact of timing and duration of thiopurine treatment on first perianal surgery in Crohn's disease: UK population-based study (1995-2009), Inflamm Bowel Dis, vol. 21, pp. 385-91, 2015.
C. C. Chi, Kirtschig, G., Aberer, W., Gabbud, J. P., Lipozencic, J., Karpati, S., Haustein, U. F., Zuberbier, T., and Wojnarowska, F., Evidence-based (S3) guideline on topical corticosteroids in pregnancy, Br J Dermatol, vol. 165, pp. 943-52, 2011.
C. C. Chi, Mayon-White, R. T., and Wojnarowska, F. T., Safety of topical corticosteroids in pregnancy: a population-based cohort study, J Invest Dermatol, vol. 131, pp. 884-91, 2011.
K. Chidwick, Strongman, H., Matthews, A., Stanway, S., Lyon, A. R., Smeeth, L., and Bhaskaran, K., Statin use in cancer survivors versus the general population: cohort study using primary care data from the UK clinical practice research datalink, BMC Cancer, vol. 18, p. 1018, 2018.
E. Chiquette, Oral, E. A., Garg, A., Araujo-Vilar, D., and Dhankhar, P., Estimating the prevalence of generalized and partial lipodystrophy: findings and challenges, Diabetes Metab Syndr Obes, vol. 10, pp. 375-383, 2017.
C. W. Choi, Kim, G. H., Song, C. S., Wang, S. G., Lee, B. J., I, H., Kang, D. H., and Song, G. A., Is obesity associated with gastropharyngeal reflux disease?, World J Gastroenterol, vol. 14, pp. 265-71, 2008.
J. Chollet, Saragoussi, D., Clay, E., and Francois, C., A clinical research practice datalink analysis of antidepressant treatment patterns and health care costs in generalized anxiety disorder, Value Health, vol. 16, pp. 1133-9, 2013.
I. J. Chou, Kuo, C. F., Tanasescu, R., Tench, C. R., Tiley, C. G., Constantinescu, C. S., and Whitehouse, W. P., Comorbidity in multiple sclerosis: its temporal relationships with disease onset and dose effect on mortality, Eur J Neurol, 2019.
T. P. Chu, Shah, A., Walker, D., and Coleman, M. P., Where are the opportunities for an earlier diagnosis of primary intracranial tumours in children and young adults?, Eur J Paediatr Neurol, vol. 21, pp. 388-395, 2017.
T. P. C. Chu, Moran, G. W., and Card, T. R., The Pattern of Underlying Cause of Death in Patients with Inflammatory Bowel Disease in England: A Record Linkage Study, J Crohns Colitis, vol. 11, pp. 578-585, 2017.
T. P. C. Chu, Grainge, M. J., and Card, T. R., The risk of venous thromboembolism during and after hospitalisation in patients with inflammatory bowel disease activity, Aliment Pharmacol Ther, vol. 48, pp. 1099-1108, 2018.
T. P. Chu, Shah, A., Walker, D., and Coleman, M. P., Pattern of symptoms and signs of primary intracranial tumours in children and young adults: a record linkage study, Arch Dis Child, vol. 100, pp. 1115-22, 2015.
C. S. Chui, Chan, E. W., Wong, A. Y., Root, A., Douglas, I. J., and Wong, I. C., Association between oral fluoroquinolones and seizures: A self-controlled case series study, Neurology, vol. 86, pp. 1708-15, 2016.
A. T. Clarke, Johnson, P. C., Hall, G. C., Ford, I., and Mills, P. R., High Dose Atorvastatin Associated with Increased Risk of Significant Hepatotoxicity in Comparison to Simvastatin in UK GPRD Cohort, PLoS One, vol. 11, p. e0151587, 2016.
L. E. Clarson, Hider, S. L., Belcher, J., Roddy, E., and Mallen, C. D., Factors Influencing Allopurinol Initiation in Primary Care, Ann Fam Med, vol. 15, pp. 557-560, 2017.
L. E. Clarson, Hider, S. L., Belcher, J., Heneghan, C., Roddy, E., and Mallen, C. D., Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink, Ann Rheum Dis, vol. 74, pp. 642-7, 2015.
P. Cleary, Shorvon, S., and Tallis, R., Late-onset seizures as a predictor of subsequent stroke, Lancet, vol. 363, pp. 1184-6, 2004.
G. M. Clifford, Logie, J., and Farmer, R. D., No risk of drug-associated liver injury with alpha1-adrenoreceptor blocking agents in men with BPH: results from an observational study using the GPRD, Pharmacoepidemiol Drug Saf, vol. 14, pp. 75-80, 2005.
G. M. Clifford, Logie, J., and Farmer, R. D., How do symptoms indicative of BPH progress in real life practice? The UK experience, Eur Urol, vol. 38 Suppl 1, pp. 48-53, 2000.
G. M. Clifford and Farmer, R. D., Drug or symptom-induced depression in men treated with alpha 1-blockers for benign prostatic hyperplasia? A nested case-control study, Pharmacoepidemiol Drug Saf, vol. 11, pp. 55-61, 2002.
H. Close, Mason, J. M., Wilson, D. W., Hungin, A. P., Jones, R., and Rubin, G., Risk of Ischaemic Heart Disease in Patients with Inflammatory Bowel Disease: Cohort Study Using the General Practice Research Database, PLoS One, vol. 10, p. e0139745, 2015.
H. Close, Reilly, J., Mason, J. M., Kripalani, M., Wilson, D., Main, J., and Hungin, A. P., Renal failure in lithium-treated bipolar disorder: a retrospective cohort study, PLoS One, vol. 9, p. e90169, 2014.
H. Close, Mason, J. M., Wilson, D., and Hungin, A. P., Hormone replacement therapy is associated with gastro-oesophageal reflux disease: a retrospective cohort study, BMC Gastroenterol, vol. 12, p. 56, 2012.
A. T. Cohen, Katholing, A., Rietbrock, S., Bamber, L., and Martinez, C., Epidemiology of first and recurrent venous thromboembolism in patients with active cancer. A population-based cohort study, Thromb Haemost, vol. 117, pp. 57-65, 2017.
C. Cohet, Haguinet, F., G. Santos, D., Webb, D., Logie, J., G. Ferreira, L., Rosillon, D., and Shinde, V., Effect of the adjuvanted (AS03) A/H1N1 2009 pandemic influenza vaccine on the risk of rejection in solid organ transplant recipients in England: a self-controlled case series, BMJ Open, vol. 6, p. e009264, 2016.
J. J. Coleman, McDowell, S. E., Evans, S. J., Gill, P. S., and Ferner, R. E., Oversight: a retrospective study of biochemical monitoring in patients beginning antihypertensive drug treatment in primary care, Br J Clin Pharmacol, vol. 70, pp. 109-17, 2010.
[Page last reviewed 4 November 2019]