Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 December 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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K. H. Thomas, Martin, R. M., Davies, N. M., Metcalfe, C., Windmeijer, F., and Gunnell, D., “Smoking cessation treatment and risk of depression, suicide, and self harm in the Clinical Practice Research Datalink: prospective cohort study”, Bmj, vol. 347, p. f5704, 2013.
R. Boggon, Timmis, A., Hemingway, H., Raju, S., Malvestiti, F. M., and van Staa, T. P., “Smoking cessation interventions following acute coronary syndrome: a missed opportunity?”, Eur J Prev Cardiol, vol. 21, pp. 767-73, 2014.
J. V. Been, Szatkowski, L., van Staa, T. P., Leufkens, H. G., van Schayck, O. C., Sheikh, A., de Vries, F., and Souverein, P., “Smoke-free legislation and the incidence of paediatric respiratory infections and wheezing/asthma: interrupted time series analyses in the four UK nations”, Sci Rep, vol. 5, p. 15246, 2015.
X. Xiao, Fischbach, S., Zhang, T., Chen, C., Sheng, Q., Zimmerman, R., Patnaik, S., Fusco, J., Ming, Y., Guo, P., Shiota, C., Prasadan, K., Gangopadhyay, N., Husain, S. Z., Dong, H., and Gittes, G. K., “SMAD3/Stat3 Signaling Mediates beta-Cell Epithelial-Mesenchymal Transition in Chronic Pancreatitis-Related Diabetes”, Diabetes, vol. 66, pp. 2646-2658, 2017.
K. T. Palmer, D'Angelo, S., Harris, E. C., Linaker, C., Sayer, A. A., Gale, C. R., Evandrou, M., Van Staa, T., Cooper, C., and Coggon, D., “Sleep disturbance and the older worker: findings from the Health and Employment after Fifty study”, Scand J Work Environ Health, vol. 43, pp. 136-145, 2017.
D. F. Carr, O'Meara, H., Jorgensen, A. L., Campbell, J., Hobbs, M., McCann, G., Van Staa, T., and Pirmohamed, M., “SLCO1B1 genetic variant associated with statin-induced myopathy: a proof-of-concept study using the clinical practice research datalink”, Clin Pharmacol Ther, vol. 94, pp. 695-701, 2013.
R. L. Tannen, Weiner, M. G., Xie, D., and Barnhart, K., “A simulation using data from a primary care practice database closely replicated the women's health initiative trial”, J Clin Epidemiol, vol. 60, pp. 686-95, 2007.
R. L. Tannen, Weiner, M. G., and Marcus, S. M., “Simulation of the Syst-Eur randomized control trial using a primary care electronic medical record was feasible”, J Clin Epidemiol, vol. 59, pp. 254-64, 2006.
T. P. van Staa, Geusens, P., Pols, H. A., de Laet, C., Leufkens, H. G., and Cooper, C., “A simple score for estimating the long-term risk of fracture in patients using oral glucocorticoids”, Qjm, vol. 98, pp. 191-8, 2005.
M. T. Bazelier, van Staa, T. P., Uitdehaag, B. M., Cooper, C., Leufkens, H. G., Vestergaard, P., Bentzen, J., and de Vries, F., “A simple score for estimating the long-term risk of fracture in patients with multiple sclerosis”, Neurology, vol. 79, pp. 922-8, 2012.
R. S. Padwal, Klarenbach, S. W., Wang, X., Sharma, A. M., Karmali, S., Birch, D. W., and Majumdar, S. R., “A simple prediction rule for all-cause mortality in a cohort eligible for bariatric surgery”, JAMA Surg, vol. 148, pp. 1109-15, 2013.
T. M. McKeever, Lewis, S. A., Smith, C., Collins, J., Heatlie, H., Frischer, M., and Hubbard, R., “Siblings, multiple births, and the incidence of allergic disease: a birth cohort study using the West Midlands general practice research database”, Thorax, vol. 56, pp. 758-62, 2001.
M. Frischer, Heatlie, H., Chapman, S., Norwood, J., Bashford, J., and Millson, D., “Should the corticosteroid to bronchodilator ratio be promoted as a quality prescribing marker?”, Public Health, vol. 113, pp. 247-50, 1999.
S. Weir, Samnaliev, M., Kuo, T. C., Tierney, T. S., S. Autiero, W., Taylor, R. S., and Schrag, A., “Short- and long-term cost and utilization of health care resources in Parkinson's disease in the UK”, Mov Disord, vol. 33, pp. 974-981, 2018.
J. M. Dennis, Henley, W. E., Weedon, M. N., Lonergan, M., Rodgers, L. R., Jones, A. G., Hamilton, W. T., Sattar, N., Janmohamed, S., Holman, R. R., Pearson, E. R., Shields, B. M., and Hattersley, A. T., “Sex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes: A Framework for Evaluating Stratification Using Routine Clinical and Individual Trial Data”, Diabetes Care, vol. 41, pp. 1844-1853, 2018.
K. M. Abel, Heatlie, H. F., Howard, L. M., and Webb, R. T., “Sex- and age-specific incidence of fractures in mental illness: a historical, population-based cohort study”, J Clin Psychiatry, vol. 69, pp. 1398-403, 2008.
F. de Vries, van Staa, T. P., Bracke, M. S., Cooper, C., Leufkens, H. G., and Lammers, J. W., “Severity of obstructive airway disease and risk of osteoporotic fracture”, Eur Respir J, vol. 25, pp. 879-84, 2005.
H. P. Booth, Prevost, A. T., and Gulliford, M. C., “Severity of obesity and management of hypertension, hypercholesterolaemia and smoking in primary care: population-based cohort study”, J Hum Hypertens, vol. 30, pp. 40-5, 2016.
J. T. Nielen, Emans, P. J., Dagnelie, P. C., Boonen, A., Lalmohamed, A., de Boer, A., van den Bemt, B. J., and de Vries, F., “Severity of Diabetes Mellitus and Total Hip or Knee Replacement: A Population-Based Case-Control Study”, Medicine (Baltimore), vol. 95, p. e3739, 2016.
M. Iwagami, Mansfield, K. E., Hayes, J. F., Walters, K., Osborn, D. P., Smeeth, L., Nitsch, D., and Tomlinson, L. A., “Severe mental illness and chronic kidney disease: a cross-sectional study in the United Kingdom”, Clin Epidemiol, vol. 10, pp. 421-429, 2018.
R. J. Silverwood, Forbes, H. J., Abuabara, K., Ascott, A., Schmidt, M., Schmidt, S. A. J., Smeeth, L., and Langan, S. M., “Severe and predominantly active atopic eczema in adulthood and long term risk of cardiovascular disease: population based cohort study”, Bmj, vol. 361, p. k1786, 2018.
H. Furuland, McEwan, P., Evans, M., Linde, C., Ayoubkhani, D., Bakhai, A., Palaka, E., Bennett, H., and Qin, L., “Serum potassium as a predictor of adverse clinical outcomes in patients with chronic kidney disease: new risk equations using the UK clinical practice research datalink”, BMC Nephrol, vol. 19, p. 211, 2018.
C. Linde, Qin, L., Bakhai, A., Furuland, H., Evans, M., Ayoubkhani, D., Palaka, E., Bennett, H., and McEwan, P., “Serum potassium and clinical outcomes in heart failure patients: results of risk calculations in 21 334 patients in the UK”, ESC Heart Fail, 2019.
M. Schmidt, Mansfield, K. E., Bhaskaran, K., Nitsch, D., Sorensen, H. T., Smeeth, L., and Tomlinson, L. A., “Serum creatinine elevation after renin-angiotensin system blockade and long term cardiorenal risks: cohort study”, Bmj, vol. 356, p. j791, 2017.
C. Renoux, Lix, L. M., Patenaude, V., Bresee, L. C., Paterson, J. M., Lafrance, J. P., Tamim, H., Mahmud, S. M., Alsabbagh, M. W., Hemmelgarn, B., Dormuth, C. R., and Ernst, P., “Serotonin-Norepinephrine Reuptake Inhibitors and the Risk of AKI: A Cohort Study of Eight Administrative Databases and Meta-Analysis”, Clin J Am Soc Nephrol, vol. 10, pp. 1716-22, 2015.
J. C. Wilson, Sarsour, K., Collinson, N., Tuckwell, K., Musselman, D., Klearman, M., Napalkov, P., Jick, S. S., Stone, J. H., and Meier, C. R., “Serious adverse effects associated with glucocorticoid therapy in patients with giant cell arteritis (GCA): A nested case-control analysis”, Semin Arthritis Rheum, vol. 46, pp. 819-827, 2017.
K. T. Palmer, D'Angelo, S., Harris, E. C., Linaker, C., and Coggon, D., “Sensory impairments, problems of balance and accidental injury at work: a case-control study”, Occup Environ Med, vol. 72, pp. 195-9, 2015.
R. A. Charlton, McGrogan, A., Snowball, J., Yates, L. M., Wood, A., Clayton-Smith, J., Smithson, W. H., Richardson, J. L., McHugh, N., Thomas, S. H., Baker, G. A., and Bromley, R., “Sensitivity of the UK Clinical Practice Research Datalink to Detect Neurodevelopmental Effects of Medicine Exposure in Utero: Comparative Analysis of an Antiepileptic Drug-Exposed Cohort”, Drug Saf, vol. 40, pp. 387-397, 2017.
S. F. Liang, Taweel, A., Miles, S., Kovalchuk, Y., Spiridou, A., Barratt, B., Hoang, U., Crichton, S., Delaney, B. C., and Wolfe, C., “Semi automated transformation to OWL formatted files as an approach to data integration. A feasibility study using environmental, disease register and primary care clinical data”, Methods Inf Med, vol. 54, pp. 32-40, 2015.
C. Morgan, Webb, R. T., Carr, M. J., Kontopantelis, E., Chew-Graham, C. A., Kapur, N., and Ashcroft, D. M., “Self-harm in a primary care cohort of older people: incidence, clinical management, and risk of suicide and other causes of death”, Lancet Psychiatry, vol. 5, pp. 905-912, 2018.
F. Zaccardi, Husemoen, L. L. Nystrup, Thorsted, B. L., Webb, D. R., Paul, S. K., Davies, M. J., and Khunti, K., “Selectivity of beta-blockers, cardiovascular and all-cause mortality in people with hypoglycaemia: An observational study”, Nutr Metab Cardiovasc Dis, vol. 29, pp. 481-488, 2019.
C. Becker, Jick, S. S., and Meier, C. R., “Selective Serotonin Reuptake Inhibitors and Cataract Risk: A Case-Control Analysis”, Ophthalmology, vol. 124, pp. 1635-1639, 2017.
J. Busby, Mills, K., Zhang, S. D., Liberante, F. G., and Cardwell, C. R., “Selective serotonin reuptake inhibitor use and breast cancer survival: a population-based cohort study”, Breast Cancer Res, vol. 20, p. 4, 2018.
M. Gulliford, Latinovic, R., Charlton, J., Little, P., Van Staa, T., and Ashworth, M., “Selective decrease in consultations and antibiotic prescribing for acute respiratory tract infections in UK primary care up to 2006”, J Public Health (Oxf), vol. 31, pp. 512-20, 2009.
E. A. Shephard and Hamilton, W. T., “Selection of men for investigation of possible testicular cancer in primary care: a large case-control study using electronic patient records”, Br J Gen Pract, vol. 68, pp. e559-e565, 2018.
M. C. Gulliford, Charlton, J., Ashworth, M., Rudd, A. G., and Toschke, A. M., “Selection of medical diagnostic codes for analysis of electronic patient records. Application to stroke in a primary care database”, PLoS One, vol. 4, p. e7168, 2009.
P. Imfeld, Bodmer, M., Schuerch, M., Jick, S. S., and Meier, C. R., “Seizures in patients with Alzheimer's disease or vascular dementia: a population-based nested case-control analysis”, Epilepsia, vol. 54, pp. 700-7, 2013.
V. Schneider-Lindner, Quach, C., Hanley, J. A., and Suissa, S., “Secular trends of antibacterial prescribing in UK paediatric primary care”, J Antimicrob Chemother, vol. 66, pp. 424-33, 2011.
R. Y. van der Velde, Wyers, C. E., Curtis, E. M., Geusens, P., van den Bergh, J. P. W., de Vries, F., Cooper, C., van Staa, T. P., and Harvey, N. C., “Secular trends in fracture incidence in the UK between 1990 and 2012”, Osteoporos Int, vol. 27, pp. 3197-3206, 2016.
L. A. Garcia Rodriguez and Ruigomez, A., “Secondary prevention of upper gastrointestinal bleeding associated with maintenance acid-suppressing treatment in patients with peptic ulcer bleed”, Epidemiology, vol. 10, pp. 228-32, 1999.
S. A. Julious, Campbell, M. J., Bianchi, S. M., and Murray-Thomas, T., “Seasonality of medical contacts in school-aged children with asthma: association with school holidays”, Public Health, vol. 125, pp. 769-76, 2011.
J. D. Lewis, Aberra, F. N., Lichtenstein, G. R., Bilker, W. B., Brensinger, C., and Strom, B. L., “Seasonal variation in flares of inflammatory bowel disease”, Gastroenterology, vol. 126, pp. 665-73, 2004.
S. Muller, Hider, S., Machin, A., Stack, R., Hayward, R. A., Raza, K., and Mallen, C., “Searching for a prodrome for rheumatoid arthritis in the primary care record: A case-control study in the clinical practice research datalink”, Semin Arthritis Rheum, 2018.
C. C. Chi, Mayon-White, R. T., and Wojnarowska, F. T., “Safety of topical corticosteroids in pregnancy: a population-based cohort study”, J Invest Dermatol, vol. 131, pp. 884-91, 2011.
V. 3rd. Lo Re, Haynes, K., Ming, E. E., J. Ives, W., Horne, L. N., Fortier, K., Carbonari, D. M., Hennessy, S., Cardillo, S., Reese, P. P., Reddy, K. R., Margolis, D., Apter, A., Kimmel, S. E., Roy, J., Freeman, C. P., Razzaghi, H., Holick, C. N., Esposito, D. B., van Staa, T. P., Bhullar, H., and Strom, B. L., “Safety of saxagliptin: rationale for and design of a series of postmarketing observational studies”, Pharmacoepidemiol Drug Saf, vol. 21, pp. 1202-15, 2012.
L. A. Garcia-Rodriguez, Masso-Gonzalez, E. L., Wallander, M. A., and Johansson, S., “The safety of rosuvastatin in comparison with other statins in over 100,000 statin users in UK primary care”, Pharmacoepidemiol Drug Saf, vol. 17, pp. 943-52, 2008.
M. C. Gulliford, Moore, M. V., Little, P., Hay, A. D., Fox, R., Prevost, A. T., Juszczyk, D., Charlton, J., and Ashworth, M., “Safety of reduced antibiotic prescribing for self limiting respiratory tract infections in primary care: cohort study using electronic health records”, Bmj, vol. 354, p. i3410, 2016.
K. Donegan, King, B., and Bryan, P., “Safety of pertussis vaccination in pregnant women in UK: observational study”, Bmj, vol. 349, p. g4219, 2014.
P. Bryan, Seabroke, S., Wong, J., Donegan, K., Webb, E., Goldsmith, C., Vipond, C., and Feavers, I., “Safety of multicomponent meningococcal group B vaccine (4CMenB) in routine infant immunisation in the UK: a prospective surveillance study”, Lancet Child Adolesc Health, vol. 2, pp. 395-403, 2018.
J. R. Hardy, Leaderer, B. P., Holford, T. R., Hall, G. C., and Bracken, M. B., “Safety of medications prescribed before and during early pregnancy in a cohort of 81,975 mothers from the UK General Practice Research Database”, Pharmacoepidemiol Drug Saf, vol. 15, pp. 555-64, 2006.
[Page last reviewed 6 December 2019]