Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,700 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 6 April 2021) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 5MB, 226 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 2770 results:
Author Title [ Type(Asc)] Year
Journal Article
R. K. Akyea, Kai, J., Qureshi, N., Iyen, B., and Weng, S. F., Sub-optimal cholesterol response to initiation of statins and future risk of cardiovascular disease, Heart, 2019.
N. A. Stohler, Reinau, D., Jick, S. S., Bodmer, D., and Meier, C. R., A study on the epidemiology of tinnitus in the United Kingdom, Clin Epidemiol, vol. 11, pp. 855-871, 2019.
J. Spoendlin, Voegel, J. J., Jick, S. S., and Meier, C. R., A study on the epidemiology of rosacea in the U.K, Br J Dermatol, vol. 167, pp. 598-605, 2012.
S. S. Jick, Vasilakis, C., Martinez, C., and Jick, H., A study of the relation of exposure to quinolones and suicidal behaviour, Br J Clin Pharmacol, vol. 45, pp. 77-81, 1998.
R. D. Mann, Lis, Y., Chukwujindu, J., and Chanter, D. O., A study of the association between hormone replacement therapy, smoking and the occurrence of myocardial infarction in women, J Clin Epidemiol, vol. 47, pp. 307-12, 1994.
K. Phiri, Hallas, J., Linder, M., Margulis, A., Suehs, B., Arana, A., Bahmanyar, S., Hoffman, V., Enger, C., Horter, L., Odsbu, I., Olesen, M., Perez-Gutthann, S., Kristiansen, N. S., Appenteng, K., de Vogel, S., and Seeger, J., A study of cancer occurrence in users of mirabegron and antimuscarinic treatments for overactive bladder, Curr Med Res Opin, p. 1, 2021.
S. Norton, Koduri, G., Nikiphorou, E., Dixey, J., Williams, P., and Young, A., A study of baseline prevalence and cumulative incidence of comorbidity and extra-articular manifestations in RA and their impact on outcome, Rheumatology (Oxford), vol. 52, pp. 99-110, 2013.
T. P. van Staa and Sprafka, J. M., Study of adverse outcomes in women using testosterone therapy, Maturitas, vol. 62, pp. 76-80, 2009.
A. Pate, Barrowman, M., Webb, D., Pimenta, J. M., Davis, K. J., Williams, R., Van Staa, T., and Sperrin, M., Study investigating the generalisability of a COPD trial based in primary care (Salford Lung Study) and the presence of a Hawthorne effect, BMJ Open Respir Res, vol. 5, p. e000339, 2018.
J. Fortuny, Gilsenan, A., Cainzos-Achirica, M., Cantero, O. F., Flynn, R. W. V., Garcia-Rodriguez, L., Kollhorst, B., Karlsson, P., Linner, L., MacDonald, T. M., Plana, E., Ruigomez, A., Schink, T., Ziemiecki, R., and Andrews, E. B., Study Design and Cohort Comparability in a Study of Major Cardiovascular Events in New Users of Prucalopride Versus Polyethylene Glycol 3350, Drug Saf, 2019.
J. R. Hardy, Holford, T. R., Hall, G. C., and Bracken, M. B., Strategies for identifying pregnancies in the automated medical records of the General Practice Research Database, Pharmacoepidemiol Drug Saf, vol. 13, pp. 749-59, 2004.
P. Bidulka, Fu, E. L., Leyrat, C., Kalogirou, F., McAllister, K. S. L., Kingdon, E. J., Mansfield, K. E., Iwagami, M., Smeeth, L., Clase, C. M., Bhaskaran, K., van Diepen, M., Carrero, J. J., Nitsch, D., and Tomlinson, L. A., Stopping renin-angiotensin system blockers after acute kidney injury and risk of adverse outcomes: parallel population-based cohort studies in English and Swedish routine care, BMC Med, vol. 18, p. 195, 2020.
J. Blackwell, Saxena, S., Jayasooriya, N., Petersen, I., Hotopf, M., Creese, H., Bottle, A., and Pollok, R. C. G., Stoma formation in Crohn's Disease and the likelihood of antidepressant use: a population-based cohort study, Clin Gastroenterol Hepatol, 2020.
N. Frey, Bodmer, M., Bircher, A., Jick, S. S., Meier, C. R., and Spoendlin, J., Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Association with Commonly Prescribed Drugs in Outpatient Care Other than Anti-Epileptic Drugs and Antibiotics: A Population-Based Case-Control Study, Drug Saf, vol. 42, pp. 55-66, 2019.
S. Hernandez-Diaz and Rodriguez, L. A., Steroids and risk of upper gastrointestinal complications, Am J Epidemiol, vol. 153, pp. 1089-93, 2001.
V. Chhaya, Saxena, S., Cecil, E., Subramanian, V., Curcin, V., Majeed, A., and Pollok, R. C., Steroid dependency and trends in prescribing for inflammatory bowel disease - a 20-year national population-based study, Aliment Pharmacol Ther, vol. 44, pp. 482-94, 2016.
A. McGrogan, Snowball, J., and Charlton, R. A., Statins during pregnancy: a cohort study using the General Practice Research Database to investigate pregnancy loss, Pharmacoepidemiol Drug Saf, vol. 26, pp. 843-852, 2017.
A. K. Sorial, Anjum, S. A., Cook, M. J., Board, T. N., and O'Neill, T. W., Statins, bone biology and revision arthroplasty: review of clinical and experimental evidence, Ther Adv Musculoskelet Dis, vol. 12, p. 1759720x20966229, 2020.
A. F. Macedo, Douglas, I., Smeeth, L., Forbes, H., and Ebrahim, S., Statins and the risk of type 2 diabetes mellitus: cohort study using the UK clinical practice pesearch datalink, BMC Cardiovasc Disord, vol. 14, p. 85, 2014.
R. G. Schlienger, Fedson, D. S., Jick, S. S., Jick, H., and Meier, C. R., Statins and the risk of pneumonia: a population-based, nested case-control study, Pharmacotherapy, vol. 27, pp. 325-32, 2007.
C. C. Yang, Jick, S. S., and Jick, H., Statins and the risk of idiopathic venous thromboembolism, Br J Clin Pharmacol, vol. 53, pp. 101-5, 2002.
H. Jick, Zornberg, G. L., Jick, S. S., Seshadri, S., and Drachman, D. A., Statins and the risk of dementia, Lancet, vol. 356, pp. 1627-31, 2000.
K. Tascilar, Dell'Aniello, S., Hudson, M., and Suissa, S., Statins and Risk of Rheumatoid Arthritis: A Nested Case-Control Study, Arthritis Rheumatol, vol. 68, pp. 2603-2611, 2016.
M. C. Bradley, Hughes, C. M., Cantwell, M. M., and Murray, L. J., Statins and pancreatic cancer risk: a nested case-control study, Cancer Causes Control, vol. 21, pp. 2093-100, 2010.
S. S. Jick and Bradbury, B. D., Statins and newly diagnosed diabetes, Br J Clin Pharmacol, vol. 58, pp. 303-9, 2004.
G. J. Lefeber, Koek, H. L., Souverein, P. C., Bouvy, M. L., de Boer, A., and Knol, W., Statins After Myocardial Infarction in the Oldest: A Cohort Study in the Clinical Practice Research Datalink Database, J Am Geriatr Soc, 2019.
G. J. Lefeber, Knol, W., Souverein, P. C., Bouvy, M. L., de Boer, A., and Koek, H. L., Statins After Ischemic Stroke in the Oldest: A Cohort Study Using the Clinical Practice Research Datalink Database, Stroke, p. Strokeaha120030755, 2021.
L. Alexandre, Clark, A. B., Bhutta, H. Y., Holt, S., Lewis, M. P., and Hart, A. R., Statin use is associated with reduced risk of histologic subtypes of esophageal cancer: a nested case-control analysis, Gastroenterology, vol. 146, pp. 661-8, 2014.
K. Chidwick, Strongman, H., Matthews, A., Stanway, S., Lyon, A. R., Smeeth, L., and Bhaskaran, K., Statin use in cancer survivors versus the general population: cohort study using primary care data from the UK clinical practice research datalink, BMC Cancer, vol. 18, p. 1018, 2018.
J. A. Kaye, Meier, C. R., Walker, A. M., and Jick, H., Statin use, hyperlipidaemia, and the risk of breast cancer, Br J Cancer, vol. 86, pp. 1436-9, 2002.
A. D. Spence, Busby, J., Hughes, C. M., Johnston, B. T., Coleman, H. G., and Cardwell, C. R., Statin use and survival in patients with gastric cancer in two independent population-based cohorts, Pharmacoepidemiol Drug Saf, 2018.
C. R. Cardwell, U. Menamin, M., Hughes, C. M., and Murray, L. J., Statin use and survival from lung cancer: a population-based cohort study, Cancer Epidemiol Biomarkers Prev, vol. 24, pp. 833-41, 2015.
K. A. McGlynn, Hagberg, K., Chen, J., Graubard, B. I., London, W. T., Jick, S., and Sahasrabuddhe, V. V., Statin use and risk of primary liver cancer in the Clinical Practice Research Datalink, J Natl Cancer Inst, vol. 107, 2015.
A. Sarmanova, Doherty, M., Kuo, C., Wei, J., Abhishek, A., Mallen, C., Zeng, C., Wang, Y., Lei, G., and Zhang, W., Statin use and risk of joint replacement due to osteoarthritis and rheumatoid arthritis: a propensity-score matched longitudinal cohort study, Rheumatology (Oxford), 2020.
C. Seliger, Meier, C. R., Becker, C., Jick, S. S., Bogdahn, U., Hau, P., and Leitzmann, M. F., Statin use and risk of glioma: population-based case-control analysis, Eur J Epidemiol, vol. 31, pp. 947-52, 2016.
M. Bodmer, Brauchli, Y. B., Krahenbuhl, S., Jick, S. S., and Meier, C. R., Statin use and risk of gallstone disease followed by cholecystectomy, Jama, vol. 302, pp. 2001-7, 2009.
Y. B. Brauchli, Jick, S. S., and Meier, C. R., Statin use and risk of first-time psoriasis diagnosis, J Am Acad Dermatol, vol. 65, pp. 77-83, 2011.
Z. Liu, Alsaggaf, R., McGlynn, K. A., Anderson, L. A., Tsai, H. T., Zhu, B., Zhu, Y., Mbulaiteye, S. M., Gadalla, S. M., and Koshiol, J., Statin use and reduced risk of biliary tract cancers in the UK Clinical Practice Research Datalink, Gut, 2018.
U. T. Kadam, Blagojevic, M., and Belcher, J., Statin use and clinical osteoarthritis in the general population: a longitudinal study, J Gen Intern Med, vol. 28, pp. 943-9, 2013.
J. A. Kaye and Jick, H., Statin use and cancer risk in the General Practice Research Database, Br J Cancer, vol. 90, pp. 635-7, 2004.
C. R. Cardwell, Hicks, B. M., Hughes, C., and Murray, L. J., Statin use after diagnosis of breast cancer and survival: a population-based cohort study, Epidemiology, vol. 26, pp. 68-78, 2015.
C. R. Cardwell, Hicks, B. M., Hughes, C., and Murray, L. J., Statin use after colorectal cancer diagnosis and survival: a population-based cohort study, J Clin Oncol, vol. 32, pp. 3177-83, 2014.
E. M. van de Garde, Hak, E., Souverein, P. C., Hoes, A. W., van den Bosch, J. M., and Leufkens, H. G., Statin treatment and reduced risk of pneumonia in patients with diabetes, Thorax, vol. 61, pp. 957-61, 2006.
J. Y. Shin, Eberg, M., Ernst, P., and Filion, K. B., Statin potency and the risk of hospitalization for community-acquired pneumonia, Br J Clin Pharmacol, vol. 83, pp. 1319-1327, 2017.
M. Molokhia, McKeigue, P., Curcin, V., and Majeed, A., Statin induced myopathy and myalgia: time trend analysis and comparison of risk associated with statin class from 1991-2006, PLoS One, vol. 3, p. e2522, 2008.
O. A. Oshagbemi, Burden, A. M., Braeken, D. C. W., Henskens, Y., Wouters, E. F. M., Driessen, J. H. M., van der Zee, A. H. Maitlan, de Vries, F., and Franssen, F. M. E., Stability of Blood Eosinophils in Patients with Chronic Obstructive Pulmonary Disease and in Control Subjects, and the Impact of Sex, Age, Smoking, and Baseline Counts, Am J Respir Crit Care Med, vol. 195, pp. 1402-1404, 2017.
S. H. Landis, Suruki, R., Hilton, E., Compton, C., and Galwey, N. W., Stability of Blood Eosinophil Count in Patients with COPD in the UK Clinical Practice Research Datalink, Copd, vol. 14, pp. 382-388, 2017.
I. S. Mackenzie, Morant, S. V., Wei, L., Thompson, A. M., and MacDonald, T. M., Spironolactone use and risk of incident cancers: a retrospective, matched cohort study, Br J Clin Pharmacol, vol. 83, pp. 653-663, 2017.
I. S. Mackenzie, MacDonald, T. M., Thompson, A., Morant, S., and Wei, L., Spironolactone and risk of incident breast cancer in women older than 55 years: retrospective, matched cohort study, Bmj, vol. 345, p. e4447, 2012.
D. C. Lloyd, Harris, C. M., and Roberts, D. J., Specific therapeutic group age-sex related prescribing units (STAR-PUs): weightings for analysing general practices' prescribing in England, Bmj, vol. 311, pp. 991-4, 1995.
[Page last reviewed 6 April 2021]