| 2021 |
Triple Inhaler versus Dual Bronchodilator Therapy in COPD: Real-World Effectiveness on Mortality
10.1080/15412555.2021.1977789
Authors: S. Suissa, S. Dell'Aniello, P. Ernst |
| 2021 |
UK prevalence of underlying conditions which increase the risk of severe COVID-19 disease: a point prevalence study using electronic health records
10.1186/s12889-021-10427-2
Authors: J. Walker, D. Grint, H. Strongman, R. Eggo, M. Peppa, C. Minassian, K. Mansfield, C. Rentsch, I. Douglas, R. Mathur, A. Wong, J. Quint, N. Andrews, J. Bernal, J. Scott, M. Ramsay, L. Smeeth, H. McDonald |
| 2021 |
Use of levothyroxine among pregnant women with subclinical hypothyroidism in the United Kingdom: A population-based assessment
10.1002/prp2.848
Authors: Y. Yu, K. Filion, P. Reynier, R. Platt, O. H. Y. Yu, S. Grandi |
| 2021 |
Use of menopausal hormone therapy and risk of dementia: nested case-control studies using QResearch and CPRD databases
10.1136/bmj.n2182
Authors: Y. Vinogradova, T. Dening, J. Hippisley-Cox, L. Taylor, M. Moore, C. Coupland |
| 2021 |
The use of mono- and combination drug therapy in men and women with lower urinary tract symptoms (LUTS) in the UK: a retrospective observational study
10.1186/s12894-021-00881-w
Authors: M. Ali, M. Landeira, P. Covernton, N. Choudhury, A. Jaggi, F. Fatoye, R. van Maanen |
| 2021 |
Use of prescribing safety quality improvement reports in UK general practices: a qualitative assessment
10.1186/s12913-021-06417-0
Authors: N. Khan, H. Booth, P. Myles, D. Mullett, A. Gallagher, C. Evans, N. Thomas, J. Valentine |
| 2021 |
Using Bayesian Networks to identify musculoskeletal symptoms influencing the risk of developing Psoriatic Arthritis in people with psoriasis
10.1093/rheumatology/keab310
Authors: A. Green, W. Tillett, N. McHugh, T. Smith |
| 2021 |
Using electronic health records to inform trial feasibility in a rare autoimmune blistering skin disease in England
10.1186/s12874-021-01212-1
Authors: M. Persson, K. Harman, K. Thomas, J. Chalmers, Y. Vinogradova, S. Langan, J. Hippisley-Cox, S. Gran |
| 2021 |
Utilisation and Safety of Polyethylene Glycol 3350 with Electrolytes in Children Under 2 Years: A Retrospective Cohort
10.1097/mpg.0000000000003074
Authors: D. Roy, F. Akriche, B. Amlani, S. Shakir |
| 2021 |
Utilization and long-term persistence of direct oral anticoagulants among patients with non-valvular atrial fibrillation and liver disease
10.1111/bcp.15046
Authors: A. Douros, Y. Cui, R. Platt, K. Filion, G. Sebastiani, C. Renoux |
| 2021 |
The Utilization and Safety of Umeclidinium and Umeclidinium/Vilanterol in UK Primary Care: A Retrospective Cohort Study
10.2147/copd.s291931
Authors: G. Requena, D. Dedman, J. Quint, R. Ghosh, R. Williams, J. Pimenta |
| 2021 |
Validity of an algorithm to identify cardiovascular deaths from administrative health records: a multi-database population-based cohort study
10.1186/s12913-021-06762-0
Authors: L. Lix, S. Sobhan, A. St-Jean, J. Daigle, A. Fisher, O. H. Y. Yu, S. Dell'Aniello, N. Hu, S. Bugden, B. Shah, P. Ronksley, S. Alessi-Severini, A. Douros, P. Ernst, K. Filion |
| 2021 |
Validity of bariatric surgery codes in the UK Clinical Practice Research Datalink (CPRD) GOLD compared with Hospital Episodes Statistics
10.1002/pds.5221
Authors: T. Burkard, M. Rauch, S. Jick, C. Meier |
| 2021 |
Vertebral fracture as a risk factor for self-harm: a retrospective cohort study
10.1186/s12891-021-04631-9
Authors: J. Prior, F. Crawford-Manning, R. Whittle, A. Abdul-Sultan, C. Chew-Graham, S. Muller, T. Shepherd, A. Sumathipala, C. Mallen, Z. Paskins |
| 2021 |
Weight change, cardio-metabolic risk factors and cardiovascular incidence in people with serious mental illness: protocol of a population-based cohort study in the UK from 1998 to 2020
10.1136/bmjopen-2021-053427
Authors: C. Lee, F. Waite, M. Smith, M. Gao, C. Bankhead, P. Aveyard, C. Piernas |
| 2021 |
wEight chanGes, caRdio-mEtabolic risks and morTality in patients with hyperthyroidism (EGRET): a protocol for a CPRD-HES linked cohort study
10.1136/bmjopen-2021-055219
Authors: B. Torlinska, J. Hazlehurst, K. Nirantharakumar, G. Thomas, J. Priestley, S. Finnikin, P. Saunders, K. Abrams, K. Boelaert |
| 2021 |
Weight loss and risk reduction of obesity-related outcomes in 0.5 million people: evidence from a UK primary care database
10.1038/s41366-021-00788-4
Authors: C. Haase, S. Lopes, A. Olsen, A. Satylganova, V. Schnecke, P. McEwan |
| 2021 |
What is the incidence of methotrexate or leflunomide discontinuation related to cytopenia, liver enzyme elevation or kidney function decline?
10.1093/rheumatology/keab254
Authors: G. Nakafero, M. Grainge, T. Card, C. Mallen, W. Zhang, M. Doherty, M. Taal, G. Aithal, A. Abhishek |
| 2021 |
Women with Polycystic Ovary Syndrome have an increased risk of major cardiovascular events: a population study
10.1210/clinem/dgab392
Authors: T. Berni, C. Morgan, D. Rees |
| 2021 |
Younger people with rheumatoid arthritis are at increased risk of fracture even before age 50 years: a population-based cohort study
10.1007/s00198-021-05862-1
Authors: J. Erwin, D. Enki, A. Woolf |
| 2021 |
β-blocker prescription is associated with lower cumulative risk of knee osteoarthritis and knee pain consultations in primary care: a propensity score matched cohort study
10.1093/rheumatology/keab234
Authors: G. Nakafero, M. Grainge, A. Valdes, N. Townsend, C. Mallen, W. Zhang, M. Doherty, M. Mamas, A. Abhishek |
| 2021 |
Suicide and other causes of death among working-age and older adults in the year after discharge from in-patient mental healthcare in England: matched cohort study
10.1192/bjp.2021.176
Authors: R. Musgrove, M. Carr, N. Kapur, C. Chew-Graham, F. Mughal, D. Ashcroft, R. Webb |
| 2021 |
Healthcare resource use and costs for people with type 2 diabetes mellitus with and without severe mental illness in England: longitudinal matched-cohort study using the Clinical Practice Research Datalink
10.1192/bjp.2021.131
Authors: H. Wang, L. Han, R. Jacobs, T. Doran, R. Holt, S. Prady, S. Gilbody, D. Shiers, S. Alderson, C. Hewitt, J. Taylor, C. Kitchen, S. Bellass, N. Siddiqi |
| 2021 |
The healthcare resource impact of maternal mental illness on children and adolescents: UK retrospective cohort study
10.1192/bjp.2021.65
Authors: H. Hope, C. Osam, E. Kontopantelis, S. Hughes, L. Munford, D. Ashcroft, M. Pierce, K. Abel |
| 2021 |
The Long-Term Impact of Vaginal Surgical Mesh Devices in UK Primary Care: A Cohort Study in the Clinical Practice Research Datalink
10.2147/clep.s333775
Authors: E. McFadden, S. Lay-Flurrie, C. Koshiaris, G. Richards, C. Heneghan |
| 2021 |
Does pre-existing morbidity influences risks and benefits of total hip replacement for osteoarthritis: a prospective study of 6682 patients from linked national datasets in England
10.1136/bmjopen-2020-046712
Authors: R. Ferguson, D. Prieto-Alhambra, G. Peat, A. Delmestri, K. Jordan, V . Y. Strauss, J. Valderas, C. Walker, D. Yu, S. Glyn-Jones, A. Silman |
| 2021 |
Does pre-existing morbidity influences risks and benefits of total hip replacement for osteoarthritis: a prospective study of 6682 patients from linked national datasets in England
10.1136/bmjopen-2020-046712
Authors: R. Ferguson, D. Prieto-Alhambra, G. Peat, A. Delmestri, K. Jordan, V . Y. Strauss, J. Valderas, C. Walker, D. Yu, S. Glyn-Jones, A. Silman |
| 2021 |
Sodium-Glucose Cotransporter-2 Inhibitors and Urinary Tract Infections: A Propensity Score-matched Population-based Cohort Study
10.1016/j.jcjd.2021.12.005
Authors: W. Alkabbani, A. Zongo, J. Minhas-Sandhu, D. Eurich, B. Shah, M. Alsabbagh, J. Gamble |
| 2021 |
Associations between attainment of incentivized primary care indicators and incident sight-threatening diabetic retinopathy in England: A population-based historical cohort study
10.1111/dom.14344
Authors: A. McKay, L. Gunn, M. Nugawela, T. Sathish, A. Majeed, Vamos E, G. Molina, S. Sivaprasad |
| 2021 |
Healthcare, Medication Utilization and Outcomes of Patients with COPD by GOLD Classification in England
10.2147/copd.s318969
Authors: L. Sansbury, K. Rothnie, C. Bains, C. Compton, G. Anley, A. Ismaila |
| 2021 |
Effectiveness and safety among direct oral anticoagulants in nonvalvular atrial fibrillation: A multi-database cohort study with meta-analysis
10.1111/bcp.14669
Authors: M. Durand, M. Schnitzer, M. Pang, G. Carney, S. Eltonsy, K. Filion, A. Fisher, M. Jun, I. Kuo, A. Matteau, J. Paterson, J. Quail, C. Renoux |
| 2021 |
Persistence of Eosinophilic Asthma Endotype and Clinical Outcomes: A Real-World Observational Study
10.2147/jaa.s306416
Authors: T. Tran, M. Kerkhof, V. Carter, D. Price |
| 2021 |
Lower cardiorenal risk with sodium-glucose cotransporter-2 inhibitors versus dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes without cardiovascular and renal diseases: A large multinational observational study
10.1111/dom.14189
Authors: K. Birkeland, J. Bodegard, A. Banerjee, D. Kim, A. Norhammar, J. Eriksson, M. Thuresson, S. Okami, K. Ha, N. Kossack, J. Mamza, R. Zhang, T. Yajima, I. Komuro, T. Kadowaki |
| 2021 |
Lower risk of hospitalization for heart failure, kidney disease and death with sodium-glucose co-transporter-2 inhibitors compared with dipeptidyl peptidase-4 inhibitors in type 2 diabetes regardless of prior cardiovascular or kidney disease
10.1111/dom.14437
Authors: I. Idris, R. Zhang, J. Mamza, M. Ford, T. Morris, A. Banerjee, K. Khunti |
| 2020 |
Ability of primary care health databases to assess medicinal products discussed by the European Union Pharmacovigilance Risk Assessment Committee
10.1002/cpt.1775
Authors: R. Flynn, K. Hedenmalm, T. Murray-Thomas, A. Pacurariu, P. Arlett, H. Shepherd, P. Myles, X. Kurz |
| 2020 |
Accelerated FEV(1) decline and risk of cardiovascular disease and mortality in a primary care population of COPD patients
10.1183/13993003.00918-2020
Authors: H. Whittaker, C. Bloom, A. Morgan, D. Jarvis, S. Kiddle, J. Quint |
| 2020 |
Adaptive Treatment Strategies with Survival Outcomes: An Application to the Treatment of Type 2 Diabetes using a Large Observational Database
10.1093/aje/kwz272
Authors: G. Simoneau, E. Moodie, L. Azoulay, R. Platt |
| 2020 |
Quality of life and mental health in breast cancer survivors compared with non-cancer controls: a study of patient-reported outcomes in the United Kingdom
10.1007/s11764-020-00950-3
Authors: H. Carreira, R. Williams, H. Dempsey, S. Stanway, L. Smeeth, K. Bhaskaran |
| 2020 |
Quantifying the impact of pre-existing conditions on the stage of oesophagogastric cancer at diagnosis: a primary care cohort study using electronic medical records
10.1093/fampra/cmaa132
Authors: M. Quiroga, E. Shephard, L. Mounce, M. Carney, W. Hamilton, S. Price |
| 2020 |
Real-world data on the incidence, mortality, and cost of ischaemic stroke and major bleeding events among non-valvular atrial fibrillation patients in England
10.1111/jep.13400
Authors: A. Bakhai, H. Petri, F. Vahidnia, C. Wolf, Y. Ding, N. Foskett, M. Sculpher |
| 2020 |
Real-world reproducibility study characterizing patients newly diagnosed with multiple myeloma using Clinical Practice Research Datalink, a UK-based electronic health records database
10.1002/pds.5171
Authors: A. Seesaghur, N. Petruski-Ivleva, V. Banks, J. Wang, P. Mattox, E. Hoeben, J. Maskell, D. Neasham, S. Reynolds, G. Kafatos |
| 2020 |
Recurrent heart failure hospitalizations are associated with increased cardiovascular mortality in patients with heart failure in Clinical Practice Research Datalink
10.1002/ehf2.12727
Authors: R. Lahoz, A. Fagan, M. McSharry, C. Proudfoot, S. Corda, R. Studer |
| 2020 |
Regional analysis of UK primary care prescribing and adult service referrals for young people with attention-deficit hyperactivity disorder
10.1192/bjo.2019.94
Authors: A. Price, T. Ford, A. Janssens, A. Williams, T. Newlove-Delgado |
| 2020 |
Resource use and direct medical costs of acute respiratory illness in the UK based on linked primary and secondary care records from 2001 to 2009
10.1371/journal.pone.0236472
Authors: G. Meier, J. Watkins, P. McEwan, R. Pockett |
| 2020 |
Respiratory tract infection-related healthcare utilisation in children with Down\textquoterights syndrome
10.1007/s15010-020-01408-5
Authors: L. Manikam, A. Schilder, M. Lakhanpaul, P. Littlejohns, E. Alexander, A. Hayward |
| 2020 |
Risk Factor Control and Cardiovascular Event Risk in People With Type 2 Diabetes in Primary and Secondary Prevention Settings
10.1161/circulationaha.120.046783
Authors: A. Wright, M. Suarez-Ortegon, S. Read, E. Kontopantelis, I. Buchan, R. Emsley, N. Sattar, D. Ashcroft, S. Wild, M. Rutter |
| 2020 |
Risk factors associated with the incidence and recurrence of hyperkalaemia in patients with cardiorenal conditions
10.1111/ijcp.13941
Authors: E. Tafesse, M. Hurst, L. Hoskin, K. Badora, D. Sugrue, L. Qin, G. James, P. McEwan |
| 2020 |
Risk of depression, suicide and psychosis with hydroxychloroquine treatment for rheumatoid arthritis: a multinational network cohort study
10.1093/rheumatology/keaa771
Authors: J. Lane, J. Weaver, K. Kostka, T. Duarte-Salles, M. Abrahao, H. Alghoul, O. Alser, T. Alshammari, C. Areia, P. Biedermann, J. Banda, E. Burn, P. Casajust, Fi\v ster, J. Hardin, L. Hester, G. Hripcsak, B. Kaas-Hansen, S. Khosla, S. Kolovos, K. Lynch, R. Makadia, P. Mehta, D. Morales, H. Morgan-Stewart, M. Mosseveld, D. Newby, F. Nyberg, A. Ostropolets, Woong Park, A. Prats-Uribe, G. Rao, C. Reich, P. Rijnbeek, A. Sena, A. Shoaibi, M. Spotnitz, S. Vignesh, M. Suchard, D. Vizcaya, H. Wen, M. de Wilde, J. Xie, S. You, L. Zhang, S. Lovestone, P. Ryan, D. Prieto-Alhambra |
| 2020 |
Risk of hand osteoarthritis in new users of hormone replacement therapy: A nested case-control analysis
10.1016/j.maturitas.2019.11.006
Authors: T. Burkard, M. Rauch, J. Spoendlin, D. Prieto-Alhambra, S. Jick, C. Meier |
| 2020 |
Risk of herpes zoster after exposure to varicella to explore the exogenous boosting hypothesis: self controlled case series study using UK electronic healthcare data
10.1136/bmj.l6987
Authors: H. Forbes, I. Douglas, A. Finn, J. Breuer, K. Bhaskaran, L. Smeeth, S. Packer, S. Langan, K. Mansfield, R. Marlow, H. Whitaker, C. Warren-Gash |
