Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 November 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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Export 2365 results:
Author Title [ Type(Desc)] Year
Journal Article
R. Charlton, Snowball, J., Sammon, C., and de Vries, C., “The Clinical Practice Research Datalink for drug safety in pregnancy research: an overview”, Therapie, vol. 69, pp. 83-9, 2014.
F. Nissen, Douglas, I. J., Mullerova, H., Pearce, N., Bloom, C. I., Smeeth, L., and Quint, J. K., “Clinical profile of predefined asthma phenotypes in a large cohort of UK primary care patients (Clinical Practice Research Datalink)”, J Asthma Allergy, vol. 12, pp. 7-19, 2019.
S. E. Bailey, Ukoumunne, O. C., Shephard, E. A., and Hamilton, W., “Clinical relevance of thrombocytosis in primary care: a prospective cohort study of cancer incidence using English electronic medical records and cancer registry data”, Br J Gen Pract, vol. 67, pp. e405-e413, 2017.
J. Chollet, Saragoussi, D., Clay, E., and Francois, C., “A clinical research practice datalink analysis of antidepressant treatment patterns and health care costs in generalized anxiety disorder”, Value Health, vol. 16, pp. 1133-9, 2013.
C. Black, Kaye, J. A., and Jick, H., “Clinical risk factors for venous thromboembolus in users of the combined oral contraceptive pill”, Br J Clin Pharmacol, vol. 53, pp. 637-40, 2002.
F. D. R. Hobbs, Bankhead, C., Mukhtar, T., Stevens, S., Perera-Salazar, R., Holt, T., and Salisbury, C., “Clinical workload in UK primary care: a retrospective analysis of 100 million consultations in England, 2007-14”, Lancet, vol. 387, pp. 2323-2330, 2016.
D. A. Springate, Kontopantelis, E., Ashcroft, D. M., Olier, I., Parisi, R., Chamapiwa, E., and Reeves, D., “ClinicalCodes: an online clinical codes repository to improve the validity and reproducibility of research using electronic medical records”, PLoS One, vol. 9, p. e99825, 2014.
M. J. Brodie, Chung, S., Wade, A., Quelen, C., Guiraud-Diawara, A., Francois, C., Verpillat, P., Shen, V., and Isojarvi, J., “Clobazam and clonazepam use in epilepsy: Results from a UK database incident user cohort study”, Epilepsy Res, vol. 123, pp. 68-74, 2016.
I. J. Douglas, Evans, S. J., Hingorani, A. D., Grosso, A. M., Timmis, A., Hemingway, H., and Smeeth, L., “Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs”, Bmj, vol. 345, p. e4388, 2012.
R. Boggon, van Staa, T. P., Timmis, A., Hemingway, H., Ray, K. K., Begg, A., Emmas, C., and Fox, K. A., “Clopidogrel discontinuation after acute coronary syndromes: frequency, predictors and associations with death and myocardial infarction–a hospital registry-primary care linked cohort (MINAP-GPRD)”, Eur Heart J, vol. 32, pp. 2376-86, 2011.
B. M. Hicks, Murray, L. J., Hughes, C., and Cardwell, C. R., “Clopidogrel use and cancer-specific mortality: a population-based cohort study of colorectal, breast and prostate cancer patients”, Pharmacoepidemiol Drug Saf, vol. 24, pp. 830-40, 2015.
K. J. Rothnie, Smeeth, L., Herrett, E., Pearce, N., Hemingway, H., Wedzicha, J., Timmis, A., and Quint, J. K., “Closing the mortality gap after a myocardial infarction in people with and without chronic obstructive pulmonary disease”, Heart, vol. 101, pp. 1103-10, 2015.
M. C. Gulliford, Van Staa, T., McDermott, L., Dregan, A., McCann, G., Ashworth, M., Charlton, J., Grieve, A. P., Little, P., Moore, M. V., and Yardley, L., “Cluster randomised trial in the General Practice Research Database: 1. Electronic decision support to reduce antibiotic prescribing in primary care (eCRT study)”, Trials, vol. 12, p. 115, 2011.
A. Dregan, Van Staa, T., McDermott, L., McCann, G., Ashworth, M., Charlton, J., Wolfe, C., Rudd, A., Yardley, L., and Gulliford, M., “Cluster randomized trial in the general practice research database: 2. Secondary prevention after first stroke (eCRT study): study protocol for a randomized controlled trial”, Trials, vol. 13, p. 181, 2012.
M. C. Gulliford, van Staa, T. P., McDermott, L., McCann, G., Charlton, J., and Dregan, A., “Cluster randomized trials utilizing primary care electronic health records: methodological issues in design, conduct, and analysis (eCRT Study)”, Trials, vol. 15, p. 220, 2014.
A. Bakhai, Rigney, U., Hollis, S., and Emmas, C., “Co-administration of statins with cytochrome P450 3A4 inhibitors in a UK primary care population”, Pharmacoepidemiol Drug Saf, vol. 21, pp. 485-93, 2012.
D. Metcalfe, Masters, J., Delmestri, A., Judge, A., Perry, D., Zogg, C., Gabbe, B., and Costa, M., “Coding algorithms for defining Charlson and Elixhauser co-morbidities in Read-coded databases”, BMC Med Res Methodol, vol. 19, p. 115, 2019.
N. Bhattarai, Charlton, J., Rudisill, C., and Gulliford, M. C., “Coding, recording and incidence of different forms of coronary heart disease in primary care”, PLoS One, vol. 7, p. e29776, 2012.
L. R. Rodgers, Weedon, M. N., Henley, W. E., Hattersley, A. T., and Shields, B. M., “Cohort profile for the MASTERMIND study: using the Clinical Practice Research Datalink (CPRD) to investigate stratification of response to treatment in patients with type 2 diabetes”, BMJ Open, vol. 7, p. e017989, 2017.
L. Li, Neogi, T., and Jick, S., “A cohort study of comorbidity in patients with granulomatosis with polyangiitis”, Rheumatology (Oxford), vol. 57, pp. 291-299, 2018.
S. Venkatesan, Myles, P. R., Manning, H. J., Mozid, A. M., Andersson, C., Jorgensen, M. E., Hardman, J. G., Moonesinghe, S. R., Foex, P., Mythen, M., Grocott, M. P. W., and Sanders, R. D., “Cohort study of preoperative blood pressure and risk of 30-day mortality after elective non-cardiac surgery”, Br J Anaesth, vol. 119, pp. 65-77, 2017.
P. Mangtani, Cumberland, P., Hodgson, C. R., Roberts, J. A., Cutts, F. T., and Hall, A. J., “A cohort study of the effectiveness of influenza vaccine in older people, performed using the United Kingdom general practice research database”, J Infect Dis, vol. 190, pp. 1-10, 2004.
L. A. Garcia Rodriguez, Mannino, S., Wallander, M. A., and Lindblom, B., “A cohort study of the ocular safety of anti-ulcer drugs”, Br J Clin Pharmacol, vol. 42, pp. 213-6, 1996.
L. A. Garcia Rodriguez, Duque, A., Castellsague, J., Perez-Gutthann, S., and Stricker, B. H., “A cohort study on the risk of acute liver injury among users of ketoconazole and other antifungal drugs”, Br J Clin Pharmacol, vol. 48, pp. 847-52, 1999.
J. Castellsague, Kuiper, J. G., Pottegard, A., I. Berglind, A., Dedman, D., Gutierrez, L., Calingaert, B., van Herk-Sukel, M. P., Hallas, J., Sundstrom, A., Gallagher, A. M., Kaye, J. A., Pardo, C., Rothman, K. J., and Perez-Gutthann, S., “A cohort study on the risk of lymphoma and skin cancer in users of topical tacrolimus, pimecrolimus, and corticosteroids (Joint European Longitudinal Lymphoma and Skin Cancer Evaluation - JOELLE study)”, Clin Epidemiol, vol. 10, pp. 299-310, 2018.
C. Schneider, Bodmer, M., Jick, S. S., and Meier, C. R., “Colorectal cancer and markers of anemia”, Eur J Cancer Prev, vol. 27, pp. 530-538, 2018.
R. Charlton, Snowball, J., Bloomfield, K., and de Vries, C., “Colorectal cancer incidence on the General Practice Research Database”, Pharmacoepidemiol Drug Saf, vol. 21, pp. 775-783, 2012.
R. A. Charlton, Snowball, J. M., Bloomfield, K., and de Vries, C. S., “Colorectal cancer risk reduction following macrogol exposure: a cohort and nested case control study in the UK”, PLoS One, vol. 8, p. e83203, 2013.
O. H. Yu, Yin, H., and Azoulay, L., “The combination of DPP-4 inhibitors versus sulfonylureas with metformin after failure of first-line treatment in the risk for major cardiovascular events and death”, Can J Diabetes, vol. 39, pp. 383-9, 2015.
C. L. Morgan, Mukherjee, J., Jenkins-Jones, S., Holden, S. E., and Currie, C. J., “Combination therapy with metformin plus sulphonylureas versus metformin plus DPP-4 inhibitors: association with major adverse cardiovascular events and all-cause mortality”, Diabetes Obes Metab, vol. 16, pp. 977-83, 2014.
L. Azoulay, Schneider-Lindner, V., Dell'Aniello, S., Schiffrin, A., and Suissa, S., “Combination therapy with sulfonylureas and metformin and the prevention of death in type 2 diabetes: a nested case-control study”, Pharmacoepidemiol Drug Saf, vol. 19, pp. 335-42, 2010.
J. Busby, Murray, L., Mills, K., Zhang, S. D., Liberante, F., and Cardwell, C. R., “A combined connectivity mapping and pharmacoepidemiology approach to identify existing medications with breast cancer causing or preventing properties”, Pharmacoepidemiol Drug Saf, vol. 27, pp. 78-86, 2018.
M. O. Bernier, Mikaeloff, Y., Hudson, M., and Suissa, S., “Combined oral contraceptive use and the risk of systemic lupus erythematosus”, Arthritis Rheum, vol. 61, pp. 476-81, 2009.
A. Dregan, Matcham, F., Harber-Aschan, L., Rayner, L., Brailean, A., Davis, K., Hatch, S., Pariante, C., Armstrong, D., Stewart, R., and Hotopf, M., “Common mental disorders within chronic inflammatory disorders: a primary care database prospective investigation”, Ann Rheum Dis, 2019.
A. Schultze, Graham, S., Nordstrom, B. L., Mehmud, F., and Ramagopalan, S. V., “Commonly used definitions in real-world studies may underestimate the prevalence of renal disease among nonvalvular atrial fibrillation patients”, J Comp Eff Res, 2019.
O. B. Sanni, Menamin, U. C. Mc, Cardwell, C. R., Sharp, L., Murray, L. J., and Coleman, H. G., “Commonly used medications and endometrial cancer survival: a population-based cohort study”, Br J Cancer, vol. 117, pp. 432-438, 2017.
F. Othman, Crooks, C. J., and Card, T. R., “Community acquired pneumonia incidence before and after proton pump inhibitor prescription: population based study”, Bmj, vol. 355, p. i5813, 2016.
N. M. Hawkins, Scholes, S., Bajekal, M., Love, H., O'Flaherty, M., Raine, R., and Capewell, S., “Community care in England: reducing socioeconomic inequalities in heart failure”, Circulation, vol. 126, pp. 1050-7, 2012.
L. T. A. Mounce, Price, S., Valderas, J. M., and Hamilton, W., “Comorbid conditions delay diagnosis of colorectal cancer: a cohort study using electronic primary care records”, Br J Cancer, vol. 116, pp. 1536-1543, 2017.
C. J. Crooks, West, J., and Card, T. R., “Comorbidities affect risk of nonvariceal upper gastrointestinal bleeding”, Gastroenterology, vol. 144, pp. 1384-93, 1393.e1-2; quiz e18-9, 2013.
H. Li, Hodgson, E., Watson, L., Shukla, A., and Nelson, J. J., “Comorbidities and Concomitant Medication Use in Men with Prostate Cancer or High Levels of PSA Compared to Matched Controls: A GPRD Analysis”, J Cancer Epidemiol, vol. 2012, p. 291704, 2012.
M. Feudjo-Tepie, Ferguson, S., Roddam, A., Taylor, A., Bayly, J., and Critchlow, C., “Comorbidities, bone-sparing agent prescription history and their determinants among postmenopausal women in UK primary care settings: a retrospective database study”, Arch Osteoporos, vol. 10, p. 41, 2015.
C. F. Kuo, Grainge, M. J., Mallen, C., Zhang, W., and Doherty, M., “Comorbidities in patients with gout prior to and following diagnosis: case-control study”, Ann Rheum Dis, vol. 75, pp. 210-7, 2016.
D. C. Perry, Bruce, C. E., Pope, D., Dangerfield, P., Platt, M. J., and Hall, A. J., “Comorbidities in Perthes' disease: a case control study using the General Practice Research database”, J Bone Joint Surg Br, vol. 94, pp. 1684-9, 2012.
M. A. Feudjo-Tepie, Le Roux, G., Beach, K. J., Bennett, D., and Robinson, N. J., “Comorbidities of idiopathic thrombocytopenic purpura: a population-based study”, Adv Hematol, vol. 2009, p. 963506, 2009.
F. Nyberg, Horne, L., Morlock, R., Nuevo, J., Storgard, C., Aiyer, L., Hines, D. M., Ansolabehere, X., and Chevalier, P., “Comorbidity Burden in Trial-Aligned Patients with Established Gout in Germany, UK, US, and France: a Retrospective Analysis”, Adv Ther, vol. 33, pp. 1180-98, 2016.
M. Nowakowska, Zghebi, S. S., Ashcroft, D. M., Buchan, I., Chew-Graham, C., Holt, T., Mallen, C., van Marwijk, H., Peek, N., Perera-Salazar, R., Reeves, D., Rutter, M. K., Weng, S. F., Qureshi, N., Mamas, M. A., and Kontopantelis, E., “The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort”, BMC Med, vol. 17, p. 145, 2019.
I. J. Chou, Kuo, C. F., Tanasescu, R., Tench, C. R., Tiley, C. G., Constantinescu, C. S., and Whitehouse, W. P., “Comorbidity in multiple sclerosis: its temporal relationships with disease onset and dose effect on mortality”, Eur J Neurol, 2019.
R. G. de Jong, Gallagher, A. M., Herrett, E., Masclee, A. A., Janssen-Heijnen, M. L., and de Vries, F., “Comparability of the age and sex distribution of the UK Clinical Practice Research Datalink and the total Dutch population”, Pharmacoepidemiol Drug Saf, vol. 25, pp. 1460-1464, 2016.
S. Khalid, Calderon-Larranaga, S., Hawley, S., Ali, M. S., Judge, A., Arden, N., Van Staa, T., Cooper, C., Javaid, M. K., and Prieto-Alhambra, D., “Comparative anti-fracture effectiveness of different oral anti-osteoporosis therapies based on "real-world" data: a meta-analysis of propensity-matched cohort findings from the UK Clinical Practice Research Database and the Catalan SIDIAP Database”, Clin Epidemiol, vol. 10, pp. 1417-1431, 2018.
[Page last reviewed 4 November 2019]