Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 November 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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M. E. Nyeland, Ploug, U. J., Richards, A., L. Alvarez, G., Demuth, D., Muthutantri, A., Skovgaard, R., and Evans, M., Evaluation of the effectiveness of liraglutide and sitagliptin in type 2 diabetes: a retrospective study in UK primary care, Int J Clin Pract, vol. 69, pp. 281-91, 2015.
F. Nyberg, Horne, L., Morlock, R., Nuevo, J., Storgard, C., Aiyer, L., Hines, D. M., Ansolabehere, X., and Chevalier, P., Comorbidity Burden in Trial-Aligned Patients with Established Gout in Germany, UK, US, and France: a Retrospective Analysis, Adv Ther, vol. 33, pp. 1180-98, 2016.
B. I. Nwaru, Simpson, C. R., Sheikh, A., and Kotz, D., External validation of a COPD prediction model using population-based primary care data: a nested case-control study, Sci Rep, vol. 7, p. 44702, 2017.
B. Numbere, Fleming, K. M., Walker, A., and Card, T. R., Adrenergic blockers and the risk for common solid cancers: a case-control study, Eur J Cancer Prev, vol. 26, pp. 86-93, 2017.
M. Nowakowska, Zghebi, S. S., Ashcroft, D. M., Buchan, I., Chew-Graham, C., Holt, T., Mallen, C., van Marwijk, H., Peek, N., Perera-Salazar, R., Reeves, D., Rutter, M. K., Weng, S. F., Qureshi, N., Mamas, M. A., and Kontopantelis, E., The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort, BMC Med, vol. 17, p. 145, 2019.
M. Nowakowska, Van Staa, T., Molter, A., Ashcroft, D. M., Tsang, J. Y., White, A., Welfare, W., and Palin, V., Antibiotic choice in UK general practice: rates and drivers of potentially inappropriate antibiotic prescribing, J Antimicrob Chemother, 2019.
S. Norton, Koduri, G., Nikiphorou, E., Dixey, J., Williams, P., and Young, A., A study of baseline prevalence and cumulative incidence of comorbidity and extra-articular manifestations in RA and their impact on outcome, Rheumatology (Oxford), vol. 52, pp. 99-110, 2013.
E. Nortoft, Chubb, B., and Borglykke, A., Obesity and healthcare resource utilization: comparative results from the UK and the USA, Obes Sci Pract, vol. 4, pp. 41-45, 2018.
K. Noakes, Pebody, R. G., Gungabissoon, U., Stowe, J., and Miller, E., Pneumococcal polysaccharide vaccine uptake in England, 1989-2003, prior to the introduction of a vaccination programme for older adults, J Public Health (Oxf), vol. 28, pp. 242-7, 2006.
D. Nitsch, Douglas, I., Smeeth, L., and Fletcher, A., Age-related macular degeneration and complement activation-related diseases: a population-based case-control study, Ophthalmology, vol. 115, pp. 1904-10, 2008.
F. Nissen, Douglas, I. J., Mullerova, H., Pearce, N., Bloom, C. I., Smeeth, L., and Quint, J. K., Clinical profile of predefined asthma phenotypes in a large cohort of UK primary care patients (Clinical Practice Research Datalink), J Asthma Allergy, vol. 12, pp. 7-19, 2019.
F. Nissen, Morales, D. R., Mullerova, H., Smeeth, L., Douglas, I. J., and Quint, J. K., Concomitant diagnosis of asthma and COPD: a quantitative study in UK primary care, Br J Gen Pract, vol. 68, pp. e775-e782, 2018.
F. Nissen, Morales, D. R., Mullerova, H., Smeeth, L., Douglas, I. J., and Quint, J. K., Validation of asthma recording in the Clinical Practice Research Datalink (CPRD), BMJ Open, vol. 7, p. e017474, 2017.
A. L. Nightingale, Davidson, J. E., Molta, C. T., Kan, H. J., and McHugh, N. J., Presentation of SLE in UK primary care using the Clinical Practice Research Datalink, Lupus Sci Med, vol. 4, p. e000172, 2017.
A. L. Nightingale, Lawrenson, R. A., Simpson, E. L., Williams, T. J., MacRae, K. D., and Farmer, R. D., The effects of age, body mass index, smoking and general health on the risk of venous thromboembolism in users of combined oral contraceptives, Eur J Contracept Reprod Health Care, vol. 5, pp. 265-74, 2000.
A. L. Nightingale, Farmer, R. D., and de Vries, C. S., Systemic lupus erythematosus prevalence in the UK: methodological issues when using the General Practice Research Database to estimate frequency of chronic relapsing-remitting disease, Pharmacoepidemiol Drug Saf, vol. 16, pp. 144-51, 2007.
A. L. Nightingale and Farmer, R. D., Ischemic stroke in young women: a nested case-control study using the UK General Practice Research Database, Stroke, vol. 35, pp. 1574-8, 2004.
A. L. Nightingale, Farmer, R. D., and de Vries, C. S., Incidence of clinically diagnosed systemic lupus erythematosus 1992-1998 using the UK General Practice Research Database, Pharmacoepidemiol Drug Saf, vol. 15, pp. 656-61, 2006.
J. T. Nielen, Dagnelie, P. C., Emans, P. J., Veldhorst-Janssen, N., Lalmohamed, A., van Staa, T. P., Boonen, A. E., van den Bemt, B. J., and de Vries, F., Safety and efficacy of new oral anticoagulants and low-molecular-weight heparins compared with aspirin in patients undergoing total knee and hip replacements, Pharmacoepidemiol Drug Saf, vol. 25, pp. 1245-1252, 2016.
J. T. Nielen, Emans, P. J., Dagnelie, P. C., Boonen, A., Lalmohamed, A., de Boer, A., van den Bemt, B. J., and de Vries, F., Severity of Diabetes Mellitus and Total Hip or Knee Replacement: A Population-Based Case-Control Study, Medicine (Baltimore), vol. 95, p. e3739, 2016.
J. T. Nielen, de Vries, F., Dagnelie, P. C., van den Bemt, B. J., Emans, P. J., Lalmohamed, A., de Boer, A., and Boonen, A., Use of thiazolidinediones and the risk of elective hip or knee replacement: a population based case-control study, Br J Clin Pharmacol, vol. 81, pp. 370-8, 2016.
J. T. Nielen, van den Bemt, B. J., Boonen, A., Dagnelie, P. C., Emans, P. J., Veldhorst, N., Lalmohamed, A., van Staa, T. P., and de Vries, F., Identification of antithrombotic drugs related to total joint replacement using anonymised free-text notes: a search strategy in the Clinical Practice Research Datalink, BMJ Open, vol. 5, p. e009017, 2015.
J. T. H. Nielen, Dagnelie, P. C., Boonen, A., Klungel, O., van den Bemt, B., and de Vries, F., Impact of the definition of osteoarthritis and of the timing of its onset on the association between type 2 diabetes mellitus and osteoarthritis: Clinical Practice Research Datalink, Diabetes Res Clin Pract, vol. 148, pp. 240-248, 2019.
A. Nicholson, Rait, G., Murray-Thomas, T., Hughes, G., Mercer, C. H., and Cassell, J., Management of epididymo-orchitis in primary care: results from a large UK primary care database, Br J Gen Pract, vol. 60, pp. e407-22, 2010.
A. Nicholson, Rait, G., Murray-Thomas, T., Hughes, G., Mercer, C. H., and Cassell, J., Management of first-episode pelvic inflammatory disease in primary care: results from a large UK primary care database, Br J Gen Pract, vol. 60, pp. e395-406, 2010.
A. Nicholson, Ford, E., Davies, K. A., Smith, H. E., Rait, G., Tate, A. R., Petersen, I., and Cassell, J., Optimising use of electronic health records to describe the presentation of rheumatoid arthritis in primary care: a strategy for developing code lists, PLoS One, vol. 8, p. e54878, 2013.
J. M. Nicholas, Ridsdale, L., Richardson, M. P., Ashworth, M., and Gulliford, M. C., Trends in antiepileptic drug utilisation in UK primary care 1993-2008: cohort study using the General Practice Research Database, Seizure, vol. 21, pp. 466-70, 2012.
J. M. Nicholas, Ridsdale, L., Richardson, M. P., Grieve, A. P., and Gulliford, M. C., Fracture risk with use of liver enzyme inducing antiepileptic drugs in people with active epilepsy: cohort study using the general practice research database, Seizure, vol. 22, pp. 37-42, 2013.
E. Ng, McGrail, K. M., and Johnson, J. A., Hospitalization risk in a type 2 diabetes cohort, Health Rep, vol. 21, pp. 29-35, 2010.
A. Newnham, Ryan, R., Khunti, K., and Majeed, A., Prevalence of diagnosed diabetes mellitus in general practice in England and Wales, 1994 to 1998, Health Stat Q, pp. 5-13, 2002.
T. Newlove-Delgado, Ford, T. J., Hamilton, W., Stein, K., and Ukoumunne, O. C., Prescribing of medication for attention deficit hyperactivity disorder among young people in the Clinical Practice Research Datalink 2005-2013: analysis of time to cessation, Eur Child Adolesc Psychiatry, vol. 27, pp. 29-35, 2018.
T. Newlove-Delgado, Hamilton, W., Ford, T. J., Stein, K., and Ukoumunne, O. C., Prescribing for young people with attention deficit hyperactivity disorder in UK primary care: analysis of data from the Clinical Practice Research Datalink, Atten Defic Hyperact Disord, 2019.
T. Newlove-Delgado, Ford, T. J., Hamilton, W., Janssens, A., Stein, K., and Ukoumunne, O. C., Resumption of attention-deficit hyperactivity disorder medication in early adulthood: findings from a UK primary care prescribing study, Eur Child Adolesc Psychiatry, 2019.
R. D. Neal, Din, N. U., Hamilton, W., Ukoumunne, O. C., Carter, B., Stapley, S., and Rubin, G., Comparison of cancer diagnostic intervals before and after implementation of NICE guidelines: analysis of data from the UK General Practice Research Database, Br J Cancer, vol. 110, pp. 584-92, 2014.
I. Nazareth, King, M., Haines, A., Rangel, L., and Myers, S., Accuracy of diagnosis of psychosis on general practice computer system, Bmj, vol. 307, pp. 32-4, 1993.
I. Nazareth, King, M., Haines, A., Tai, S. S., and Hall, G., Care of schizophrenia in general practice, Bmj, vol. 307, p. 910, 1993.
I. Nazareth, King, M., and Davies, S., Care of schizophrenia in general practice: the general practitioner and the patient, Br J Gen Pract, vol. 45, pp. 343-7, 1995.
V. Navaratnam, Millett, E. R., Hurst, J. R., Thomas, S. L., Smeeth, L., Hubbard, R. B., Brown, J., and Quint, J. K., Bronchiectasis and the risk of cardiovascular disease: a population-based study, Thorax, vol. 72, pp. 161-166, 2017.
G. Nakafero, Sanders, R. D., Nguyen-Van-Tam, J. S., and Myles, P. R., Association between benzodiazepine use and exacerbations and mortality in patients with asthma: a matched case-control and survival analysis using the United Kingdom Clinical Practice Research Datalink, Pharmacoepidemiol Drug Saf, vol. 24, pp. 793-802, 2015.
G. Nakafero, Sanders, R. D., Nguyen-Van-Tam, J. S., and Myles, P. R., The association between benzodiazepines and influenza-like illness-related pneumonia and mortality: a survival analysis using UK Primary Care data, Pharmacoepidemiol Drug Saf, vol. 25, pp. 1263-1273, 2016.
G. Nakafero, Grainge, M. J., Myles, P. R., Mallen, C. D., Zhang, W., Doherty, M., Nguyen-Van-Tam, J. S., and Abhishek, A., Association between inactivated influenza vaccine and primary care consultations for autoimmune rheumatic disease flares: a self-controlled case series study using data from the Clinical Practice Research Datalink, Ann Rheum Dis, 2019.
G. Nakafero, Grainge, M., Valdes, A., Townsend, N., Mallen, C., Zhang, W., Doherty, M., Mamas, M. A., and Abhishek, A., Do beta-adrenoreceptor blocking drugs associate with reduced risk of symptomatic osteoarthritis and total joint replacement in the general population? A primary care-based, prospective cohort study using the Clinical Practice Research Datalink, BMJ Open, vol. 9, p. e032050, 2019.
G. Nakafero, Grainge, M. J., Myles, P. R., Mallen, C. D., Zhang, W., Doherty, M., Nguyen-Van-Tam, J. S., and Abhishek, A., Predictors and temporal trend of flu vaccination in auto-immune rheumatic diseases in the UK: a nationwide prospective cohort study, Rheumatology (Oxford), vol. 57, pp. 1726-1734, 2018.
N. S. Nagra, Robinson, D. E., Douglas, I., Delmestri, A., Dakin, S. G., Snelling, S. J. B., Carr, A. J., and Prieto-Alhambra, D., Antibiotic treatment and flares of rheumatoid arthritis: a self-controlled case series study analysis using CPRD GOLD, Sci Rep, vol. 9, p. 8941, 2019.
[Page last reviewed 4 November 2019]