2022 |
Estimating the incidence and key risk factors of cardiovascular disease in patients at high risk of imminent fracture using routinely collected real-world data from the UK
10.1002/jbmr.4648
Authors: M. Pineda-Moncusí, L. El-Hussein, A. Delmestri, C. Cooper, M. Alireza, C. Libanati, E. Toth, D. Prieto-Alhambra, S. Khalid |
2022 |
Primary care contacts, continuity, identification of palliative care needs, and hospital use: a population-based cohort study in people dying with dementia
10.3399/bjgp.2021.0715
Authors: J. Leniz, M. Gulliford, I. Higginson, S. Bajwah, D. Yi, W. Gao, K. Sleeman |
2022 |
Are we missing lifetime COPD diagnosis among people with COPD recorded death?
10.3399/bjgpo.2022.0060
Authors: A. Gayle, A. Lenoir, C. Minelli, J. Quint |
2022 |
The temporal relationship between severe mental illness diagnosis and chronic physical comorbidity: a UK primary care cohort study of disease burden over 10 years
10.1016/s2215-0366(22)00225-5
Authors: N. Launders, L. Kirsh, D. Osborn, J. Hayes |
2022 |
The Duration and Magnitude of Post-Discharge Venous Thromboembolism Following Colectomy
10.1097/sla.0000000000005563
Authors: C. Lewis-Lloyd, D. Humes, J. West, O. Peacock, C. Crooks |
2022 |
Incretin-Based Drugs and the Risk of Acute Liver Injury Among Patients With Type 2 Diabetes
10.2337/dc22-0712
Authors: R. Pradhan, H. Yin, O. H. Y. Yu, L. Azoulay |
2022 |
Management of anxiety disorders among children and adolescents in UK primary care: A cohort study
10.1016/j.jad.2022.07.002
Authors: L. Cybulski, D. Ashcroft, M. Carr, S. Garg, C. Chew-Graham, N. Kapur, R. Webb |
2022 |
Use of sodium-glucose cotransporter-2 inhibitors and the risk for sudden cardiac arrest and for all-cause death in patients with type 2 diabetes mellitus
10.1093/ehjcvp/pvac043
Authors: T. Eroglu, R. Coronel, C. Zuurbier, M. Blom, A. de Boer, P. Souverein |
2022 |
Real-World Effectiveness of Beta-Blockers versus Other Antihypertensives in Reducing All-Cause Mortality and Cardiovascular Events
10.1155/2022/6124559
Authors: Caroline Foch, Arthur Allignol, Ulrike Hostalek, Emmanuelle Boutmy, Thilo Hohenberger, Bing Niu |
2022 |
Non-steroidal anti-inflammatory drugs and risk of myocardial infarction adjusting for use of proton pump-inhibitors in patients with no major risk factors: a nested case-control study in the UK Clinical Practice Research Datalink
10.1093/ehjcvp/pvac041
Authors: B. Baak, S. Jick |
2022 |
Differences in severe exacerbations rates and healthcare utilisation in COPD populations in the UK and France
10.1136/bmjresp-2021-001150
Authors: H. Whittaker, E. Van Ganse, F. Dalon, M. Nolin, C. Marrant-Micallef, C. Pison, D. Ryan, G. Deslee, J. Quint, M. Belhassen |
2022 |
Incidence and associations of hospital delirium diagnoses in 85,979 people with severe mental illness: A data linkage study
10.1111/acps.13480
Authors: Y. Bauernfreund, N. Launders, G. Favarato, J. Hayes, D. Osborn, E. Sampson |
2022 |
Treatment patterns and clinical and economic burden of hip dislocation following primary total hip arthroplasty in England
10.1302/0301-620x.104b7.bjj-2021-1732.r1
Authors: T. Galvain, J. Mantel, O. Kakade, T. Board |
2022 |
Inflammatory marker testing in primary care in the year before Hodgkin lymphoma diagnosis: a UK population-based case-control study in patients aged ≤50 years
10.3399/bjgp.2021.0617
Authors: M. Rafiq, G. Abel, C. Renzi, G. Lyratzopoulos |
2022 |
The Association of Long-Acting Insulin Analogue Use Versus Neutral Protamine Hagedorn Insulin Use With Major Adverse Cardiovascular Events Among Individuals With Type 2 Diabetes: A Population-Based Cohort Study
10.1111/dom.14802
Authors: V. Brunetti, O. H. Y. Yu, R. Platt, K. Filion |
2022 |
Polycystic ovary syndrome and risk of adverse obstetric outcomes: a retrospective population-based matched cohort study in England
10.1186/s12916-022-02473-3
Authors: A. Subramanian, S. Lee, K. Phillips, K. Toulis, P. Kempegowda, M. O'Reilly, N. Adderley, S. Thangaratinam, W. Arlt, K. Nirantharakumar |
2022 |
Patterns of rates of mortality in the Clinical Practice Research Datalink
10.1371/journal.pone.0265709
Authors: J. Schmidt, P. Lambert, C. Gillies, M. Sweeting |
2022 |
Characterization of Patients with Chronic Obstructive Pulmonary Disease Initiating Single-Inhaler Long-Acting Muscarinic Antagonist/Long-Acting β(2)-Agonist Dual Therapy in a Primary Care Setting in England
10.2147/copd.s365480
Authors: G. Requena, V. Banks, A. Czira, R. Wood, T. Tritton, R. Wild, C. Compton, M. Duarte, A. Ismaila |
2022 |
The incidence of fractures at various sites in newly treated patients with type 2 diabetes mellitus
10.1016/j.bonr.2022.101614
Authors: C. Sarodnik, N. Rasmussen, S. Bours, N. Schaper, P. Vestergaard, P. Souverein, M. Jensen, J. Driessen, J. van den Bergh |
2022 |
Preventing unscheduled hospitalisations from asthma: a retrospective cohort study using routine primary and secondary care data in the UK (The PUSH-Asthma Study)-protocol paper
10.1136/bmjopen-2021-058356
Authors: N. Simms-Williams, P. Nagakumar, R. Thayakaran, N. Adderley, R. Hotham, A. Mansur, K. Nirantharakumar, S. Haroon |
2022 |
Single-Inhaler Triple versus Dual Bronchodilator Therapy in COPD: Real-World Comparative Effectiveness and Safety
10.2147/copd.s378486
Authors: S. Suissa, S. Dell'Aniello, P. Ernst |
2022 |
Assessing the external validity of the SAFEHEART risk prediction model in patients with familial hypercholesterolaemia in an English routine care cohort
10.1016/j.atherosclerosis.2022.07.011
Authors: A. McKay, L. Gunn, K. Ray |
2022 |
Blood pressure and risk of venous thromboembolism: a cohort analysis of 5.5 million UK adults and Mendelian randomization studies
10.1093/cvr/cvac135
Authors: M. Nazarzadeh, Z. Bidel, H. Mohseni, D. Canoy, A. Pinho-Gomes, A. Hassaine, A. Dehghan, D. Tregouet, N. Smith, K. Rahimi |
2022 |
Revising the Suspected-Cancer Guidelines: Impacts on Patients' Primary Care Contacts and Costs
10.1016/j.jval.2022.06.017
Authors: S. Price, P. Landa, R. Mujica-Mota, W. Hamilton, A. Spencer |
2022 |
Impact of von Willebrand Disease on Women's Health Outcomes: A Matched Cohort Database Study
10.1089/jwh.2022.0082
Authors: K. Hagberg, S. Jick, P. Du, Truong Berthoz, G. Ozen, S. Tzivelekis |
2022 |
Non-fatal overdose risk during and after opioid agonist treatment: A primary care cohort study with linked hospitalisation and mortality records
10.1016/j.lanepe.2022.100489
Authors: E. Domzaridou, M. Carr, R. Webb, T. Millar, D. Ashcroft |
2022 |
Identifying Patients with Bicuspid Aortic Valve Disease in UK Primary Care: A Case-Control Study and Prediction Model
10.3390/jpm12081290
Authors: W. Evans, R. Akyea, S. Weng, J. Kai, N. Qureshi |
2022 |
Trends in Prescribing Preferences for Antidiabetic Medications Among Patients With Type 2 Diabetes in the U.K. With and Without Chronic Kidney Disease, 2006-2020
10.2337/dc22-0224
Authors: J. Liaw, M. Harhay, S. Setoguchi, T. Gerhard, C. Dave |
2022 |
Risk Assessment of Acute Myocardial Infarction and Stroke Associated with Long-Acting Muscarinic Antagonists, Alone or in Combination, versus Long-Acting beta2-Agonists
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Authors: C. Rebordosa, E. Plana, A. Rubino, J. Aguado, D. Martinez, A. Lei, S. Daoud, N. Saigi-Morgui, S. Perez-Gutthann, E. Rivero-Ferrer |
2022 |
Reproducibility of real-world evidence studies using clinical practice data to inform regulatory and coverage decisions
10.1038/s41467-022-32310-3
Authors: S. Wang, S. Sreedhara, S. Schneeweiss |
2022 |
Real-world bleeding in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) and prescribed different combinations of dual antiplatelet therapy (DAPT) in England
10.1136/openhrt-2022-001999
Authors: M. Pufulete, J. Harris, K. Pouwels, B. Reeves, D. Lasserson, Y. Loke, A. Mumford, K. Mahadevan, T. Johnson |
2022 |
Elevated triglycerides and reduced high-density lipoprotein cholesterol are independently associated with the onset of advanced chronic kidney disease: a cohort study of 911,360 individuals from the United Kingdom
10.1186/s12882-022-02932-2
Authors: M. Weldegiorgis, M. Woodward |
2022 |
Safety of off-label dose reduction of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation
10.1111/bcp.15534
Authors: C. van den Dries, R. Pajouheshnia, H. van den Ham, P. Souverein, K. Moons, A. Hoes, G. Geersing, S. van Doorn |
2022 |
Systematic approach to outcome assessment from coded electronic healthcare records in the DaRe2THINK NHS-embedded randomized trial
https://doi.org/10.1093/ehjdh/ztac046
Authors: X. Wang, A.R. Mobley, O. Tica, K. Okoth, R.E. Ghosh, P. Myles, T. Williams, S. Haynes, K. Nirantharakumar, D. Shukla, D. Kotecha |
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Prognostic model for atrial fibrillation after cardiac surgery: a UK cohort study
10.1007/s00392-022-02068-1
Authors: S. Chung, B. O'Brien, G. Lip, K. Fields, J. Muehlschlegel, A. Thakur, D. Clifton, G. Collins, P. Watkinson, R. Providencia |
2022 |
Liver blood marker testing in UK primary care: a UK wide cohort study, 2004-2016
10.1136/bmjopen-2021-058967
Authors: P. Scutt, L. Ban, T. Card, C. Crooks, N. Guha, J. West, J. Morling |
2022 |
Obesity as a modifier of the cardiovascular effectiveness of sodium-glucose cotransporter-2 inhibitors in type 2 diabetes
10.1016/j.diabres.2022.110094
Authors: K. Suissa, S. Schneeweiss, A. Douros, H. Yin, E. Patorno, L. Azoulay |
2022 |
Association between continuity of primary care and both prescribing and adherence of common cardiovascular medications: a cohort study among patients in England
10.1136/bmjopen-2022-063282
Authors: P. Tammes, R. Payne, C. Salisbury |
2022 |
Changing co-morbidity and increasing deprivation among people living with HIV: UK population-based cross-sectional study
10.1111/hiv.13389
Authors: P. McGettigan, D. Morales, D. Moreno-Martos, N. Matin |
2022 |
Low Adherence to Kidney Disease: Improving Global Outcomes 2012 CKD Clinical Practice Guidelines Despite Clear Evidence of Utility
10.1016/j.ekir.2022.05.033
Authors: G. James, J. Sanchez, J. Carrero, S. Kumar, R. Pecoits-Filho, H. Heerspink, S. Nolan, C. Lam, H. Chen, E. Kanda, N. Kashihara, M. Arnold, M. Kosiborod, M. Lainscak, C. Pollock, D. Wheeler |
2022 |
The incidence rate of planned and emergency physical health hospital admissions in people diagnosed with severe mental illness: a cohort study
10.1017/s0033291722002811
Authors: N. Launders, J. Hayes, G. Price, L. Marston, D. Osborn |
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Safety of Apremilast in Patients with Psoriasis and Psoriatic Arthritis: Findings from the UK Clinical Practice Research Datalink
10.1007/s40264-022-01235-7
Authors: R. Persson, M. Cordey, M. Paris, S. Jick |
2022 |
Comparing clinical trial population representativeness to real-world populations: an external validity analysis encompassing 43 895 trials and 5 685 738 individuals across 989 unique drugs and 286 conditions in England
10.1016/s2666-7568(22)00186-6
Authors: Y . Y. Tan, V. Papez, W. Chang, S. Mueller, S. Denaxas, A. Lai |
2022 |
Association Between Gout Flare and Subsequent Cardiovascular Events Among Patients With Gout
10.1001/jama.2022.11390
Authors: E. Cipolletta, L. Tata, G. Nakafero, A. Avery, M. Mamas, A. Abhishek |
2022 |
Social and spatial inequalities in healthcare use among people living with dementia in England (2002-2016)
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Authors: J. Watson, M. Green, C. Giebel, F. Darlington-Pollock, A. Akpan |
2022 |
Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.3 million individuals
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2022 |
Characterisation of patients with chronic obstructive pulmonary disease initiating single-device inhaled corticosteroids/long-acting β(2)-agonist dual therapy in a primary care setting in England
10.1136/bmjresp-2022-001243
Authors: A. Czira, V. Banks, G. Requena, R. Wood, T. Tritton, R. Wild, C. Compton, M. Duarte, A. Ismaila |
2022 |
Translating and evaluating historic phenotyping algorithms using SNOMED CT
10.1093/jamia/ocac158
Authors: M. Elkheder, A. Gonzalez-Izquierdo, Qummer Arfeen, V. Kuan, R. Lumbers, S. Denaxas, A. Shah |
2022 |
Antimicrobial drug use and the risk of glioma: A case-control study
10.1002/cam4.5222
Authors: T. Haedenkamp, M. Leitzmann, R. Linker, C. Meier, C. Becker, S. Jick, P. Hau, C. Seliger |
2022 |
Comparative Adherence and Persistence of Single- and Multiple-Inhaler Triple Therapies Among Patients with Chronic Obstructive Pulmonary Disease in an English Real-World Primary Care Setting
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Authors: D. Halpin, K. Rothnie, V. Banks, A. Czira, C. Compton, R. Wood, T. Tritton, O. Massey, R. Wild, N. Snowise, K. Nikitin, R. Sharma, A. Ismaila, C. Vogelmeier |