CPRD study: Comparing CPRD GOLD and ONS death registration data

8 April 2019

Clear information on the date of death is important for censoring in observational epidemiology, especially for analyses of mortality and for studies assessing events at the end of life.

To check the accuracy of recorded date of death in CPRD GOLD a recent study compared the database with death registration data from the Office for National Statistics (ONS).

The article in Pharmacoepidemiology and Drug Safety highlights substantial agreement between the data sources. Gallagher et al found that for censoring follow-up and calculating mortality rates, CPRD data are likely to be sufficient, as a delay in death recording of up to one month is unlikely to impact results significantly.

Where the exact date of death or the cause is important, it may be advisable to include the individually linked death registration data from the ONS.

You can read the open access article in full online:

The accuracy of date of death recording in the Clinical Practice Research Datalink GOLD database in England compared with the Office for National Statistics death registrations (Gallager et al, Pharmacoepidemiol Drug Saf. 2019; 1– 7)

Find out more about CPRD GOLD and CPRD Aurum on our primary care data web page 

See the CPRD bibliography for more than 2,200 papers using CPRD data