Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page


Date of Approval Title
17/08/2021 The Impact of COVID-19 on care for UK patients with chronic obstructive pulmonary disease (COPD) and patients with asthma
23/07/2021 Identifying the clinical risks associated with COVID-19 in patients with congenital heart disease and associated co-morbidities
09/07/2021 Managing cardiovascular disease and risk in Covid-19 patients in primary care medicine
28/06/2021 Trends in remote GP consultations and the impact of remote consultations on antibiotic prescribing pre- and during COVID - an observational study
15/06/2021 Mortality rates, risk factors and treatment patterns in patients diagnosed with moderate-to-very-severe chronic obstructive pulmonary disease in England: a retrospective observational study using CPRD data
11/06/2021 Optimal dynamic treatment regimes for the management of chronic obstructive pulmonary disease (COPD)
10/06/2021 Prescription of blood pressure lowering and lipid lowering treatment in the UK and New Zealand: a cross sectional study
10/06/2021 Epidemiology of gout, its treatment and comorbidities - a prospective cohort study using data from Clinical Practice Research Datalink (CPRD)
10/06/2021 Does ethnicity affect the recognition of palliative care needs? An observational retrospective cohort study
09/06/2021 Cost-effectiveness of osteoporotic fracture risk assessment in people with intellectual disabilities
01/06/2021 Effectiveness of vaccination policies and current treatment stratification approaches for pneumonia: A regression discontinuity analysis
28/05/2021 Prevalence, prediction, and health outcomes of cardioprotective medication reduction in the older UK population
27/05/2021 Retrospective study estimating the incidence of alcoholic hepatitis in the United Kingdom
27/05/2021 Prevalence, Incidence, and healthcare burden of generalised pustular psoriasis, palmoplantar pustulosis, and plaque psoriasis in England
26/05/2021 Comparative effects of different antidiabetic treatments on COVID-19 mortality and vascular outcomes
26/05/2021 Identifying trends and causes of hospitalisations in people with and without the top 5 chronic conditions: a population-based study
26/05/2021 Investigating the effect of influenza vaccine on acute cardiovascular events by cardiovascular risk status
26/05/2021 Comparative effects of different antidiabetic treatments on COVID-19 mortality and vascular outcomes
25/05/2021 Time to insulin initiation among second-line antidiabetics in a cohort of patients with type 2 diabetes
24/05/2021 Trends in the prevalence of menstrual disorders 2011-2020: a descriptive study of patients presenting to primary care in England