Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

 

Date of Approval Title
11/04/2016 Vaccine effectiveness of the national rotavirus vaccination programme against acute gastroenteritis in England
12/04/2016 An epidemiological study of diabetes and diabetes-related morbidities in the UK children and young adults
19/04/2016 Historical cohort study to evaluate undertreatment and disease outcomes for patients with coexisting Heart Failure and Chronic Obstructive Pulmonary Disease
20/04/2016 Characterization of patients with COPD by mepolizumab eligibility criteria
20/04/2016 Association Between Blood Eosinophil Level and Exacerbation Risk in Patients with COPD
20/04/2016 Developing and validating a risk prediction model based on frailty syndrome using primary care data
20/04/2016 The epidemiology and treatment patterns of patients with Gastro-oesophageal reflux disease (GORD) in routine general practice.
21/04/2016 Assessing drivers of effectiveness and safety using real life data: anticoagulants as a case study
21/04/2016 Urinary tract infections in the elderly - care pathways and characteristics
21/04/2016 A prevalence and incidence study of multimorbidity in the UK using the Clinical Practice Research Datalink (CPRD)
21/04/2016 A Retrospective Descriptive Study of the Cohort of Type 2 Diabetes Mellitus Patients Initiating a Second-line Therapy in the United Kingdom Clinical Practice Research Datalink (CPRD) Database
21/04/2016 Determinants of exacerbations of asthma
29/04/2016 Premature mortality and non-fatal self-harm in patients diagnosed with Chronic Fatigue Syndrome
03/05/2016 Treatment choice and outcomes associated with dry powder inhaler and Tiotropium Respimat monotherapy in COPD (chronic obstructive pulmonary disease) patients
03/05/2016 Descriptive Epidemiology of Multimorbidity in Primary Care: A Cross-Sectional Study
12/05/2016 Does the use of inhaled corticosteroids increase the incidence and disease burden of Type 2 Diabetes, osteoporosis or pneumonia compared to non-ICS therapies in patients with Chronic Obstructive Pulmonary Disease.
17/05/2016 Estimation of multi-treatment effects from observational data with application to diabetes mellitus
17/05/2016 Burden of medically attended acute gastroenteritis and aetiology: a cohort study in CPRD in England.
18/05/2016 Development of an identification tool for patients over 65 years at risk of death or emergency hospital admission during cold weather.
23/05/2016 The utilization and toxicity profile of oral corticosteroids among asthma patients in the UK: an epidemiological study using Data from the Clinical Practice Research Datalink (CPRD).