Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page


Date of Approval Title
14/03/2016 Child Outcome REVIEW Programme: Chronic Disability
14/03/2016 Low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglyceride and diverse non-cardiovascular diseases: a large population-based cohort study using CALIBER dataset
14/03/2016 Treatment of uncomplicated mild hypertension in Primary Care
14/03/2016 Benign and Malignant Tumors in Patients with Myotonic Dystrophy Type I
17/03/2016 The risk of cardiovascular related death following cytomegalovirus (CMV) infection in England: an open cohort study using data from the Clinical Practice Research Datalink (CPRD)
24/03/2016 Disease clusters and multimorbidity patterns: a UK population cohort study
24/03/2016 Feasibility of using physician notes and discharge letters to assess potential benefits of early identification of subjects with cognitive deterioration
24/03/2016 Evaluating the impact of NICE guidelines for suspected cancers in respect of diagnostic interval and other outcomes
24/03/2016 Hyperglycaemia and early detection of pancreatic cancer
31/03/2016 Risk of eczema in children: a population-based study
31/03/2016 Post-marketing study of ropinirole prolonged release tablets in Parkinson's disease: Evaluation outcomes associated with long term use of Ropinirole-PR using the UK clinical practice research datalink (UK-CPRD)
11/04/2016 Vaccine effectiveness of the national rotavirus vaccination programme against acute gastroenteritis in England
11/04/2016 Hematological malignancies in patients with systemic lupus erythematosus versus matched controls: a population-based study in the United Kingdom.
12/04/2016 An epidemiological study of diabetes and diabetes-related morbidities in the UK children and young adults
19/04/2016 Historical cohort study to evaluate undertreatment and disease outcomes for patients with coexisting Heart Failure and Chronic Obstructive Pulmonary Disease
20/04/2016 Developing and validating a risk prediction model based on frailty syndrome using primary care data
20/04/2016 Association Between Blood Eosinophil Level and Exacerbation Risk in Patients with COPD
20/04/2016 Characterization of patients with COPD by mepolizumab eligibility criteria
20/04/2016 The epidemiology and treatment patterns of patients with Gastro-oesophageal reflux disease (GORD) in routine general practice.
21/04/2016 Determinants of exacerbations of asthma