Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

 

Date of Approval Title
06/11/2018 A retrospective examination of glaucoma patients in the CPRD database with contraindications for anti-glaucoma beta-blocker therapy
05/11/2018 Maternal and perinatal characteristics associated with Respiratory Tract Infection (RTI) healthcare utilisation and death in a birth cohort using the CPRD database and other linked databases
05/11/2018 Evaluation of probable treatment indications for the prescription of oral glycopyrronium in the United Kingdom - both licensed and off-label
31/10/2018 Respiratory Syncytial Virus (RSV) healthcare burden in England during the period 2007-2017
31/10/2018 Determine the association between RSV/bronchiolitis episodes in young children and subsequent childhood episodes of wheeze and asthma (up to age 10 years), using a birth cohort
31/10/2018 Patient and practice level factors associated with influenza vaccine uptake among adults in England: a 7-year multi-level retrospective cohort study
31/10/2018 The burden of respiratory disease in people living with HIV infection in the UK Clinical Practice Research Datalink
30/10/2018 Reproducible Evidence: Practices to Enhance and Achieve Transparency (REPEAT):Study 15 - Replication of "Concurrent use of long-acting bronchodilators in COPD and the risk of adverse cardiovascular events."
30/10/2018 Assessing the Chronicity and Burden of Hyperkalaemia in Patients with Cardiorenal Comorbidities
29/10/2018 SELECT: Selection of Eligible People for Lung Cancer Screening using Electronic Primary Care DaTa: Development of new risk prediction models
29/10/2018 Burden of meningococcal disease (MD) in the UK during the period 2008-2017 - retrospective database analysis
29/10/2018 Annual healthcare resource utilisation attributable to meningococcal disease (MD) in the UK during the period 2008-2017 – retrospective database analysis
25/10/2018 Development and validation of a prognostic model for use in primary care which estimates the probability of individuals with non-diabetic hyperglycaemia developing type 2 diabetes
25/10/2018 Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study
25/10/2018 Burden of Hypereosinophilic syndrome (HES) in the UK
24/10/2018 Dravet and Lennox-Gastaut Syndromes in the U.K.: epidemiology, patient pathways and costs.
12/10/2018 Investigating the cost-effectiveness of interventions to reduce hazardous prescribing associated with antithrombotic drugs in primary care.
12/10/2018 The treatment pathway for female patients diagnosed with breast cancer and differences due to lifestyle factors: A cohort study using the Clinical Practice Research Datalink
12/10/2018 Reproducible Evidence: Practices to Enhance and Achieve Transparency (REPEAT): Study 13 - Replication of "Metformin and the incidence of viral associated cancers in patients with type 2 diabetes."
11/10/2018 Reproducible Evidence: Practices to Enhance and Achieve Transparency (REPEAT):Study 15 - Replication of "Concurrent use of long-acting bronchodilators in COPD and the risk of adverse cardiovascular events."