Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page


Date of Approval Title
10/02/2021 Risk of tendon disorders and Psoriatic arthritis with fluoroquinolone prescriptions in Psoriasis patients
09/02/2021 Association between weight loss and healthcare resource utilization in adults living with obesity
09/02/2021 Evaluation of de novo diabetes or diabetes worsening in metastatic castration resistant prostate cancer patients treated with abiraterone acetate compared with enzalutamide in England.
02/02/2021 Real world evidence in asthma and chronic obstructive pulmonary disease to understand the burden of COVID-19 infection in United Kingdom
02/02/2021 A longitudinal study of the association between depression and glycaemic control in people with diabetes in primary care
02/02/2021 Overactive bladder anticholinergics and risk of incident dementia: a cohort study design using a triangulation approach
01/02/2021 Developing personalised risk prediction for women at increased risk of Vulval Cancer
29/01/2021 A machine learning approach to classify types of headache from laboratory blood test results
29/01/2021 Assessing the quality and uptake of incentivised physical health checks for people with serious mental illness
29/01/2021 Prediction of significant bleeding during anticoagulant use in patients with cancer-related venous thromboembolism: an English cohort study.
29/01/2021 Risk of Abnormal Uterine Bleeding associated with direct oral anticoagulants compared with Vitamin K antagonists
28/01/2021 Understanding associations between cardiometabolic and cardiac health, and risk of dementia
27/01/2021 Incidence and prevalence of heart failure in patients with idiopathic pulmonary fibrosis (IPF) between 2010 - 2019 and the impact of heart failure treatment on IPF mortality: a population-based study using CPRD Aurum
26/01/2021 Multimorbidity and health care outcomes in patients with Rheumatoid Arthritis and Psoriatic Arthritis
26/01/2021 Investigating epilepsy-related mortality among children and young people with intellectual disabilities and co-occurring epilepsy: a record linkage cohort study
26/01/2021 Urban-rural comparison of access to care and health outcomes for five major health conditions related to cardio-metabolic diseases, mental health and infectious diseases in England
25/01/2021 Prevalence and incidence of mental health conditions in children and young people with intellectual disabilities in England
21/01/2021 Cohort study of risk factors of acute and chronic cardiovascular events in COVID-19 patients
21/01/2021 Trends of gabapentinoid prescribing associated overdose and mortality in chronic pain patients and the impact of gabapentinoid classification as a controlled drug
19/01/2021 Use of renin-angiotensin-aldosterone system inhibitors and the risk of acute pancreatitis