In this study, we aim to compare the causes of mortality for those patients with comorbid chronic obstructive pulmonary disease (COPD) and heart failure (HF) to those for patients with only one of these conditions. Additionally, we will investigate whether patients with comorbid COPD-HF have a greater risk of death overall and for certain causes, than those with only one condition.
There have been many studies investigating whether having both COPD and HF results in an increased risk of mortality compared to patients with only one of these conditions; however, as of yet there is no consensus. We will use linked CPRD and ONS data to investigate changes in causes of death. We will undertake descriptive analyses to investigate changes in causes of death over time. We will analyse rates of death associated with COPD, HF, and comorbid COPD-HF stratified by age and sex.
Mortality in ONS using the derived variable as well as information from all causes mentioned on the death certificate (proposed causes).
Jennifer Quint - Chief Investigator - Imperial College London
Eleanor Axson - Corresponding Applicant - Imperial College London
Alicia Gayle - Collaborator - Imperial College London
Chloe Bloom - Collaborator - Imperial College London
ONS Death Registration Data;Patient Level Index of Multiple Deprivation