Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
09/07/2024	Sickness absence in the working age population in England before and during the COVID-19 pandemic: a retrospective cohort study using primary care medical certificate data
09/07/2024	Sickness absence in the working age population in England before and during the COVID-19 pandemic: a retrospective cohort study using primary care medical certificate data
19/06/2024	Impact of Mode of Consultation on Antimicrobial Prescribing and Health Complications for Urinary Tract Infections in Primary Care in England
14/06/2024	Changes in Cohort Characteristics and Outcomes During the COVID-19 Pandemic for Three Active Comparator, New User Cohorts
03/06/2024	Changes in healthcare, diagnosis, and treatment of acute and chronic conditions during the COVID-19 pandemic
24/05/2024	Estimating diagnosis incidence and age at diagnosis for growth-affecting conditions in UK children.
21/05/2024	Osteoporotic fractures and kidney injury in people living with an ileostomy
08/05/2024	Safety of Paxlovid Among Patients with Moderate or Severe Hepatic or Renal Impairment: Investigation of Any Safety Events and Events of Special Interest
29/04/2024	Real-world use and effectiveness of COVID-19 vaccines in pregnant women
15/04/2024	The prevalence, incidence, and mortality of Primary Raynaud's Phenomenon in England, United Kingdom.
15/04/2024	Investigating whether a new NICE (National Institute for Health and Care Excellence) indicator on chronic obstructive pulmonary disease (COPD) annual reviews for those at high risk of hospital admission can be measured using general practice data
11/04/2024	Disparities in uptake of Shingrix(R) vaccine in the eligible immunosuppressed population in England: a cohort study
11/04/2024	Feasibility study on care pathway for attention deficit hyperactive disorder between the primary and secondary care settings
10/04/2024	Target Trial Emulation of Chemoprevention of Barrett's Oesophagus: A Feasibility Study
10/04/2024	Feasibility study on dengue infection requiring general practice and hospital care
10/04/2024	Feasibility study: identifying Dravet Syndrome and Lennox-Gastaut Syndrome from all epilepsies recorded in Clinical Practice DataLIink linked to Hospital Episodes Statistics datasets
10/04/2024	Target Trial Emulation of Chemoprevention of Barrett's Oesophagus: A Feasibility Study
10/04/2024	Feasibility study on dengue infection requiring general practice and hospital care
10/04/2024	Feasibility study: identifying Dravet Syndrome and Lennox-Gastaut Syndrome from all epilepsies recorded in Clinical Practice DataLIink linked to Hospital Episodes Statistics datasets
10/04/2024	Feasibility study on hereditary angioedemia and its treatment with androgens