Asthma is a chronic lung condition affecting over 5 million people in the UK. It is caused by inflammation of the airways which leads to symptoms such as wheezing, breathlessness and coughing. Asthma can vary in severity from mild to life-threatening and different treatments can be prescribed depending upon the symptoms a patient has. The aim of the study is to use CPRD data to observe how many children, adolescents and adults have asthma and of what severity, based upon their medication history according to the Global Initiative for asthma guidelines. This study will be used as part of a submission to the European Medical Agency regarding the size of the population with asthma.
The aim of this study is to calculate the number and percentage of patients in each of the Global Initiative for Asthma (GINA) steps outlined in the GINA guidelines and to estimate the proportion of paediatric, adolescent and adults patients within each GINA step. Within these GINA steps we aim to calculate the number of exacerbations that have occurred in the 12 months post index date using both Clinical Practice Research Datalink (CPRD) and Hospital Episode Statistics (HES) data. The exploration will be performed on two cohorts of prevalent asthma patients on two different calendar years (2014 and 2015). GINA steps will be ascribed based upon therapy combinations prescribed during the index year. Data will be presented in a tabular format with numbers and percentages shown.
Prevalence of asthma defined by GINA guidelines.
Juanzhi (Jenny) Fang - Chief Investigator - NOVARTIS
- Corresponding Applicant -
Christopher Morgan - Collaborator - Pharmatelligence Limited t/a Human Data Sciences
Ellen Hubbuck - Collaborator - Pharmatelligence Limited t/a Human Data Sciences
Sara Jenkins-Jones - Collaborator - Pharmatelligence Limited t/a Human Data Sciences
Christopher Morgan - Collaborator - Pharmatelligence Limited t/a Human Data Sciences
Ellen Hubbuck - Collaborator - Pharmatelligence Limited t/a Human Data Sciences
Sara Jenkins-Jones - Collaborator - Pharmatelligence Limited t/a Human Data Sciences
HES Accident and Emergency;HES Admitted Patient Care