COPD and Asthma can occur together, and people who have both diseases may have more respiratory symptoms, more physical impairment, consume more medical resources and have a peculiar pattern of risk factors compared to people with COPD alone. Improvements in monitoring, in the treatment and in research on COPD-Asthma overlap are necessary. This study will estimate the prevalence of COPD-asthma in the UK and how this has changed over the last 12 years. We will then investigate how mortality, and exacerbation rates differ for people with COPD-Asthma, compared to those who have COPD only.
It is not uncommon for people to have concurrent asthma and COPD, however the effect this has on health status and how common it truly is and whether it is changing over time is not well established. Using CPRD linked with HES and ONS from 2004-2016, we will determine the prevalence of asthma-COPD overlap and how this has changed over time. In addition, we will compare exacerbation rates and mortality in people with COPD-Asthma compared to those with COPD only.
Jennifer Quint - Chief Investigator - Imperial College London
Jennifer Quint - Corresponding Applicant - Imperial College London
Ian Douglas - Collaborator - London School of Hygiene & Tropical Medicine ( LSHTM )
Kieran Rothnie - Collaborator - GlaxoSmithKline Services Unlimited (UK)
Sophia Turner - Collaborator - London School of Hygiene & Tropical Medicine ( LSHTM )
HES Accident and Emergency;HES Admitted Patient Care;ONS Death Registration Data;Patient Level Index of Multiple Deprivation