Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,700 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 4 May 2021) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 5MB, 226 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 40 results:
Author Title Type [ Year(Desc)]
Filters: Author is Khunti, K.  [Clear All Filters]
K. Khunti, Danese, M. D., Kutikova, L., Catterick, D., Sorio-Vilela, F., Gleeson, M., Seshasai, S. R. Kondapa, Brownrigg, J., and Ray, K. K., Association of a Combined Measure of Adherence and Treatment Intensity With Cardiovascular Outcomes in Patients With Atherosclerosis or Other Cardiovascular Risk Factors Treated With Statins and/or Ezetimibe, JAMA Netw Open, vol. 1, p. e185554, 2018.
J. Wilding, Godec, T., Khunti, K., Pocock, S., Fox, R., Smeeth, L., Clauson, P., Fenici, P., Hammar, N., and Medina, J., Changes in HbA1c and weight, and treatment persistence, over the 18 months following initiation of second-line therapy in patients with type 2 diabetes: results from the United Kingdom Clinical Practice Research Datalink, BMC Med, vol. 16, p. 116, 2018.
M. A. Cavender, Norhammar, A., Birkeland, K. I., Jorgensen, M. E., Wilding, J. P., Khunti, K., Fu, A. Z., Bodegard, J., Blak, B. T., Wittbrodt, E., Thuresson, M., Fenici, P., Hammar, N., and Kosiborod, M., SGLT-2 Inhibitors and Cardiovascular Risk: An Analysis of CVD-REAL, J Am Coll Cardiol, vol. 71, pp. 2497-2506, 2018.
U. Desai, Kirson, N. Y., Kim, J., Khunti, K., King, S., Trieschman, E., Hellstern, M., Hunt, P. R., and Mukherjee, J., Time to Treatment Intensification After Monotherapy Failure and Its Association With Subsequent Glycemic Control Among 93,515 Patients With Type 2 Diabetes, Diabetes Care, vol. 41, pp. 2096-2104, 2018.
R. Palladino, Tabak, A. G., Khunti, K., Valabhji, J., Majeed, A., Millett, C., and Vamos, E. P., Association between pre-diabetes and microvascular and macrovascular disease in newly diagnosed type 2 diabetes, BMJ Open Diabetes Res Care, vol. 8, 2020.
B. Coles, Zaccardi, F., Ling, S., Davies, M. J., Samani, N. J., and Khunti, K., Cardiovascular events and mortality in people with and without type 2 diabetes: An observational study in a contemporary multi-ethnic population, J Diabetes Investig, 2020.
F. Zaccardi, Jacquot, E., Cortese, V., Tyrer, F., Seidu, S., Davies, M. J., and Khunti, K., Comparative effectiveness of gliclazide modified release vs sitagliptin as second-line treatment after metformin monotherapy in patients with uncontrolled type 2 diabetes, Diabetes Obes Metab, 2020.
F. Tyrer, Zaccardi, F., Khunti, K., and Morriss, R., Incidence of Depression and First-Line Antidepressant Therapy in People with Obesity and Depression in Primary Care, Obesity (Silver Spring), vol. 28, pp. 977-984, 2020.
H. J. L. Heerspink, Karasik, A., Thuresson, M., Melzer-Cohen, C., Chodick, G., Khunti, K., Wilding, J. P. H., Rodriguez, L. A. Garcia, Cea-Soriano, L., Kohsaka, S., Nicolucci, A., Lucisano, G., Lin, F. J., Wang, C. Y., Wittbrodt, E., Fenici, P., and Kosiborod, M., Kidney outcomes associated with use of SGLT2 inhibitors in real-world clinical practice (CVD-REAL 3): a multinational observational cohort study, Lancet Diabetes Endocrinol, vol. 8, pp. 27-35, 2020.
Y. Tang, Weiss, T., Liu, J., Rajpathak, S., and Khunti, K., Metformin adherence and discontinuation among patients with type 2 diabetes: A retrospective cohort study, J Clin Transl Endocrinol, vol. 20, p. 100225, 2020.
A. T. O. Nickinson, Coles, B., Zaccardi, F., Gray, L. J., Payne, T., Bown, M. J., Davies, R. S. M., Khunti, K., and Sayers, R. D., Missed Opportunities for Timely Recognition of Chronic Limb-Threatening Ischaemia in Patients Undergoing a Major Amputation: A Population Based Cohort Study Using the UK's Clinical Practice Research Datalink, Eur J Vasc Endovasc Surg, 2020.
B. Coles, Khunti, K., Booth, S., Zaccardi, F., Davies, M. J., and Gray, L. J., Prediction of type 2 diabetes risk in people with non-diabetic hyperglycaemia: model derivation and validation using UK primary care data, BMJ Open, vol. 10, p. e037937, 2020.
C. A. Lawson, Zaccardi, F., Squire, I., Okhai, H., Davies, M., Huang, W., Mamas, M., Lam, C. S. P., Khunti, K., and Kadam, U. T., Risk Factors for Heart Failure: 20-Year Population-Based Trends by Sex, Socioeconomic Status, and Ethnicity, Circ Heart Fail, vol. 13, p. e006472, 2020.
F. Zaccardi, Ling, S., Lawson, C., Davies, M. J., and Khunti, K., Severe hypoglycaemia and absolute risk of cause-specific mortality in individuals with type 2 diabetes: a UK primary care observational study, Diabetologia, 2020.
J. S. Minhas, Coles, B., Mistri, A. K., Eveson, D. J., Hussain, S. T., Potter, J. F., Khunti, K., and Robinson, T. G., What is the optimal blood pressure level for patients with atrial fibrillation treated with direct oral anticoagulants?, J Hypertens, 2020.
B. Coles, Zaccardi, F., Hvid, C., Davies, M. J., and Khunti, K., Cardiovascular events and mortality in people with type 2 diabetes and multimorbidity: A real-world study of patients followed for up to 19 years, Diabetes Obes Metab, vol. 23, pp. 218-227, 2021.
A. Banerjee, Chen, S., Pasea, L., Lai, A. G., Katsoulis, M., Denaxas, S., Nafilyan, V., Williams, B., Wong, W. K., Bakhai, A., Khunti, K., Pillay, D., Noursadeghi, M., Wu, H., Pareek, N., Bromage, D., McDonagh, T. A., Byrne, J., Teo, J. T. H., Shah, A. M., Humberstone, B., Tang, L. V., Shah, A. S. V., Rubboli, A., Guo, Y., Hu, Y., Sudlow, C. L. M., Lip, G. Y. H., and Hemingway, H., Excess deaths in people with cardiovascular diseases during the COVID-19 pandemic, Eur J Prev Cardiol, 2021.
S. Ling, Zaccardi, F., Lawson, C., Seidu, S. I., Davies, M. J., and Khunti, K., Glucose Control, Sulfonylureas, and Insulin Treatment in Elderly People With Type 2 Diabetes and Risk of Severe Hypoglycemia and Death: An Observational Study, Diabetes Care, 2021.
B. Coles, Zaccardi, F., Seidu, S., Gillies, C. L., Davies, M. J., Hvid, C., and Khunti, K., Rates and estimated cost of primary care consultations in people diagnosed with type 2 diabetes and comorbidities: A retrospective analysis of 8.9 million consultations, Diabetes Obes Metab, 2021.
R. Morriss, Tyrer, F., Zaccardi, F., and Khunti, K., Safety of antidepressants in a primary care cohort of adults with obesity and depression, PLoS One, vol. 16, p. e0245722, 2021.
[Page last reviewed 4 May 2021]