| 2018 |
Study investigating the generalisability of a COPD trial based in primary care (Salford Lung Study) and the presence of a Hawthorne effect
10.1136/bmjresp-2018-000339
Authors: A. Pate, M. Barrowman, D. Webb, J. Pimenta, K. Davis, R. Williams, T. Van Staa, M. Sperrin |
| 2018 |
Sulfonylureas as Initial Treatment for Type 2 Diabetes and the Risk of Severe Hypoglycemia
10.1016/j.amjmed.2017.09.044
Authors: O. Yu, L. Azoulay, H. Yin, K. Filion, S. Suissa |
| 2018 |
Sulfonylureas as second line drugs in type 2 diabetes and the risk of cardiovascular and hypoglycaemic events: population based cohort study
10.1136/bmj.k2693
Authors: A. Douros, S. Dell'Aniello, O. H. Y. Yu, K. Filion, L. Azoulay, S. Suissa |
| 2018 |
Supplementing electronic health records through sample collection and patient diaries: A study set within a primary care research database
10.1002/pds.4323
Authors: R. Joseph, J. Soames, M. Wright, K. Sultana, T. van Staa, W. Dixon |
| 2018 |
Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals
10.1016/s0140-6736(17)32520-5
Authors: N. Conrad, A. Judge, J. Tran, H. Mohseni, D. Hedgecott, A. Crespillo, M. Allison, H. Hemingway, J. Cleland, J. McMurray, K. Rahimi |
| 2018 |
Temporal trends in use of tests in UK primary care, 2000-15: retrospective analysis of 250 million tests
10.1136/bmj.k4666
Authors: J. O\textquoterightSullivan, S. Stevens, F. Hobbs, C. Salisbury, P. Little, B. Goldacre, C. Bankhead, J. Aronson, R. Perera, C. Heneghan |
| 2018 |
Thirteen-year trend in the persistence with vitamin K antagonists for venous thromboembolism in the UK: a cohort study
10.1080/03007995.2018.1481375
Authors: C. Martinez, A. Katholing, K. Folkerts, S. Rietbrock |
| 2018 |
Time spent at blood pressure target and the risk of death and cardiovascular diseases
10.1371/journal.pone.0202359
Authors: S. Chung, M. Pujades-Rodriguez, B. Duyx, S. Denaxas, L. Pasea, A. Hingorani, A. Timmis, B. Williams, H. Hemingway |
| 2018 |
Time to Treatment Intensification After Monotherapy Failure and Its Association With Subsequent Glycemic Control Among 93,515 Patients With Type 2 Diabetes
10.2337/dc17-0662
Authors: U. Desai, N . Y. Kirson, J. Kim, K. Khunti, S. King, E. Trieschman, M. Hellstern, P. Hunt, J. Mukherjee |
| 2018 |
Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017
10.1111/dom.13346
Authors: H. Curtis, J. Dennis, B. Shields, A. Walker, S. Bacon, A. Hattersley, A. Jones, B. Goldacre |
| 2018 |
The timing of onset of hypertensive disorders in pregnancy and the risk of incident hypertension and cardiovascular disease
10.1016/j.ijcard.2018.06.059
Authors: S. Grandi, P. Reynier, R. Platt, O. Basso, K. Filion |
| 2018 |
Timings for HbA1c testing in people with diabetes are associated with incentive payments: an analysis of UK primary care data
10.1111/dme.13810
Authors: J. Hirst, A. Farmer, M. Smith, R. Stevens |
| 2018 |
Trajectory of Total Cholesterol in the Last Years of Life Over Age 80 Years: Cohort Study of 99,758 Participants
10.1093/gerona/glx184
Authors: J. Charlton, R. Ravindrarajah, S. Hamada, S. Jackson, M. Gulliford |
| 2018 |
Treatment choice, medication adherence and glycemic efficacy in people with type 2 diabetes: a UK clinical practice database study
10.1136/bmjdrc-2018-000512
Authors: J. Gordon, P. McEwan, I. Idris, M. Evans, J. Puelles |
| 2018 |
The Trend of High-Dose Insulin Usage Among Patients with Diabetes in the UK: A Retrospective Study
10.1007/s13300-018-0515-0
Authors: I. Idris, X. Peng, X. He, D. Liu, E. Balogh, P. Kaushik, K. van Brunt |
| 2018 |
Trends and determinants of length of stay and hospital reimbursement following knee and hip replacement: evidence from linked primary care and NHS hospital records from 1997 to 2014
10.1136/bmjopen-2017-019146
Authors: E. Burn, C. Edwards, D. Murray, A. Silman, C. Cooper, N. Arden, R. Pinedo-Villanueva, D. Prieto-Alhambra |
| 2018 |
Trends in Hospital Admission for Diabetic Ketoacidosis in Adults With Type 1 and Type 2 Diabetes in England, 1998-2013: A Retrospective Cohort Study
10.2337/dc17-1583
Authors: V. Zhong, J. Juhaeri, E. Mayer-Davis |
| 2018 |
Trends in moderate and severe exacerbations among COPD patients in the UK from 2005 to 2013
10.1016/j.rmed.2018.09.010
Authors: O. Oshagbemi, S. Keene, J. Driessen, R. Jordan, E. Wouters, A. de Boer, F. de Vries, F. Franssen |
| 2018 |
Trends in the prevalence, incidence and surgical management of carpal tunnel syndrome between 1993 and 2013: an observational analysis of UK primary care records
10.1136/bmjopen-2017-020166
Authors: C. Burton, Y. Chen, L. Chesterton, D. van der Windt |
| 2018 |
Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study
10.1136/bmj.k341
Authors: E. Crellin, K. Mansfield, C. Leyrat, D. Nitsch, I. Douglas, A. Root, E. Williamson, L. Smeeth, L. Tomlinson |
| 2018 |
Under-recording of hospital bleeding events in UK primary care: a linked Clinical Practice Research Datalink and Hospital Episode Statistics study
10.2147/clep.s170304
Authors: L. McDonald, C. Sammon, M. Samnaliev, S. Ramagopalan |
| 2018 |
Underrecording of osteoarthritis in United Kingdom primary care electronic health record data
10.2147/clep.s160059
Authors: D. Yu, K. Jordan, G. Peat |
| 2018 |
Undertreatment of hypertension and hypercholesterolaemia in children and adolescents with type 1 diabetes: long-term follow-up on time trends in the occurrence of cardiovascular disease, risk factors and medications use
10.1111/bcp.13482
Authors: F. Ahmadizar, P. Souverein, A. de Boer, A. van der Zee |
| 2018 |
Urate-lowering treatment and risk of total joint replacement in patients with gout
10.1093/rheumatology/key212
Authors: C. Kuo, I. Chou, L. See, J. Chen, K. Yu, S. Luo, A. Hsieh, W. Zhang, M. Doherty |
| 2018 |
Use of Dipeptidyl Peptidase-4 Inhibitors and New-onset Rheumatoid Arthritis in Patients with Type 2 Diabetes
10.1097/ede.0000000000000891
Authors: A. Douros, D. Abrahami, H. Yin, O. H. Y. Yu, C. Renoux, M. Hudson, L. Azoulay |
| 2018 |
Use of parenteral glucocorticoids and the risk of new onset type 2 diabetes mellitus: A case-control study
10.1016/j.diabres.2018.02.010
Authors: A. Keyany, J. Nielen, P. Souverein, F. de Vries, B. van den Bemt |
| 2018 |
Use of primary care data to predict those most vulnerable to cold weather: a case-crossover analysis
10.3399/bjgp18X694829
Authors: P. Tammes, C. Sartini, I. Preston, A. Hay, D. Lasserson, R. Morris |
| 2018 |
Use of proton pump inhibitors and risk of iron deficiency: a population-based case-control study
10.1111/joim.12826
Authors: A. Tran-Duy, N. Connell, F. Vanmolkot, P. Souverein, N. de Wit, C. Stehouwer, A. Hoes, F. de Vries, A. de Boer |
| 2018 |
Use of Topical Tacrolimus and Topical Pimecrolimus in Four European Countries: A Multicentre Database Cohort Study
10.1007/s40801-018-0133-1
Authors: J. Kuiper, M. van Herk-Sukel, J. Castellsague, A. Pottegard, I. Berglind, D. Dedman, L. Gutierrez, B. Calingaert, J. Hallas, A. Sundstrom, A. Gallagher, J. Kaye, C. Pardo, K. Rothman, S. Perez-Gutthann |
| 2018 |
Using electronic health records to quantify and stratify the severity of type 2 diabetes in primary care in England: rationale and cohort study design
10.1136/bmjopen-2017-020926
Authors: S. Zghebi, M. Rutter, D. Ashcroft, C. Salisbury, C. Mallen, C. Chew-Graham, D. Reeves, H. van Marwijk, N. Qureshi, S. Weng, N. Peek, C. Planner, M. Nowakowska, M. Mamas, E. Kontopantelis |
| 2018 |
The utility of long-term blood pressure variability for cardiovascular risk prediction in primary care
10.1097/hjh.0000000000001923
Authors: S. Stevens, R. McManus, R. Stevens |
| 2018 |
Validation of Cancer Cases Using Primary Care, Cancer Registry, and Hospitalization Data in the United Kingdom
10.1097/ede.0000000000000786
Authors: A. Margulis, J. Fortuny, J. Kaye, B. Calingaert, M. Reynolds, E. Plana, L. McQuay, W. Atsma, B. Franks, S. de Vogel, S. Perez-Gutthann, A. Arana |
| 2018 |
Validation of hip osteoarthritis diagnosis recording in the UK Clinical Practice Research Datalink
10.1002/pds.4673
Authors: R. Ferguson, D. Prieto-Alhambra, C. Walker, D. Yu, J. Valderas, A. Judge, J. Griffiths, K. Jordan, G. Peat, S. Glyn-Jones, A. Silman |
| 2018 |
A validation study of the CirCom comorbidity score in an English cirrhosis population using the Clinical Practice Research Datalink
10.2147/clep.s147535
Authors: C. Crooks, J. West, P. Jepsen |
| 2018 |
Value of Free-text Comments for Validating Cancer Cases Using Primary-care Data in the United Kingdom
10.1097/ede.0000000000000856
Authors: A. Margulis, J. Fortuny, J. Kaye, B. Calingaert, M. Reynolds, E. Plana, L. McQuay, W. Atsma, B. Franks, S. de Vogel, S. Perez-Gutthann, A. Arana |
| 2018 |
Variation in Cardiovascular Risk Related to Individual Antimuscarinic Drugs Used to Treat Overactive Bladder: A UK Cohort Study
10.1002/phar.2121
Authors: A. Arana, A. Margulis, L. McQuay, R. Ziemiecki, J. Bartsch, K. Rothman, B. Franks, M. D\textquoterightSilva, K. Appenteng, C. Varas-Lorenzo, S. Perez-Gutthann |
| 2018 |
What is the impact of regulatory guidance and expiry of drug patents on dementia drug prescriptions in England? A trend analysis in the Clinical Practice Research Datalink
10.1186/s13195-018-0379-6
Authors: V. Walker, N. Davies, P. Kehoe, R. Martin |
| 2018 |
Zoster vaccination inequalities: A population based cohort study using linked data from the UK Clinical Practice Research Datalink
10.1371/journal.pone.0207183
Authors: A. Jain, J. Walker, R. Mathur, H. Forbes, S. Langan, L. Smeeth, A. van Hoek, S. Thomas |
| 2019 |
20-year trends in cause-specific heart failure outcomes by sex, socioeconomic status, and place of diagnosis: a population-based study
10.1016/s2468-2667(19)30108-2
Authors: C. Lawson, F. Zaccardi, I. Squire, S. Ling, M. Davies, C. Lam, M. Mamas, K. Khunti, U. Kadam |
| 2019 |
The accuracy of date of death recording in the Clinical Practice Research Datalink GOLD database in England compared with the Office for National Statistics death registrations
10.1002/pds.4747
Authors: A. Gallagher, D. Dedman, S. Padmanabhan, H. Leufkens, F. de Vries |
| 2019 |
ACE inhibitor use and risk of cataract: a case-control analysis
10.1136/bjophthalmol-2018-312980
Authors: C. Becker, S. Jick, C. Meier |
| 2019 |
Added value and cascade effects of inflammatory marker tests in UK primary care: a cohort study from the Clinical Practice Research Datalink
10.3399/bjgp19X704321
Authors: J. Watson, C. Salisbury, P. Whiting, J. Banks, Y. Pyne, W. Hamilton |
| 2019 |
Adherence to hepatitis A and hepatitis B multi-dose vaccination schedules among adults in the United Kingdom: a retrospective cohort study
10.1186/s12889-019-6693-5
Authors: K. Johnson, X. Lu, D. Zhang |
| 2019 |
Advantages of large medical record database for outcomes research: Insights into post-menopausal hormone therapy
10.1002/lrh2.10193
Authors: R. Tannen, K. Barnhart, J. Rubin |
| 2019 |
Allergic disease, corticosteroid use and risk of Hodgkin\textquoterights lymphoma: A UK Nationwide case-control study
10.1016/j.jaci.2019.10.033
Authors: M. Rafiq, A. Hayward, C. Warren-Gash, S. Denaxas, A. Gonzalez-Izquierdo, G. Lyratzopoulos, S. Thomas |
| 2019 |
Androgen Deprivation Therapy for Prostate Cancer and the Risk of Rheumatoid Arthritis: A Population-Based Cohort Study
10.1007/s40264-019-00847-w
Authors: A. Klil-Drori, C. Santella, K. Tascilar, H. Yin, A. Aprikian, L. Azoulay |
| 2019 |
Antibiotic choice in UK general practice: rates and drivers of potentially inappropriate antibiotic prescribing
10.1093/jac/dkz345
Authors: M. Nowakowska, T. Van Staa, A. Molter, D. Ashcroft, J . Y. Tsang, A. White, W. Welfare, V. Palin |
| 2019 |
Antibiotic exposure and \textquoterightresponse failure\textquoteright for subsequent respiratory tract infections: an observational cohort study of UK preschool children in primary care
10.3399/bjgp19X705089
Authors: O. van Hecke, A. Fuller, C. Bankhead, S. Jenkins-Jones, N. Francis, M. Moore, C. Butler, K. Wang |
| 2019 |
Antibiotic management of urinary tract infection in elderly patients in primary care and its association with bloodstream infections and all cause mortality: population based cohort study
10.1136/bmj.l525
Authors: M. Gharbi, J. Drysdale, H. Lishman, R. Goudie, M. Molokhia, A. Johnson, A. Holmes, P. Aylin |
| 2019 |
Antibiotic prescribing before and after the diagnosis of comorbidity: a cohort study using primary care electronic health records
10.1093/cid/ciz1016
Authors: P. Rockenschaub, A. Hayward, L. Shallcross |
